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Inlyta 5 mg Tablet

Manufactured byPFIZER LTD
ContainsAxitinib
Description

Inlyta 5 mg Tablet is an anticancer agent used to treat a type of cancer that originates in the cells of the kidneys called renal cell carcinoma (RCC) in adults patients. This medicine is used in patients who have not been responded successfully on a prior treatment regimen for RCC.

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Side effects

Major & minor side effects for Inlyta 5 mg Tablet

  • Decreased appetite
  • Physical weakness
  • Constipation
  • Bleeding gums
  • Blurred vision
  • Decreased urination
  • Dry mouth
  • Hair loss
  • Nausea and vomiting
  • Stomach pain
  • Unusual weight gain or loss
  • Sweating
  • Pale skin

Uses of Inlyta 5 mg Tablet

What is it prescribed for?

  • Renal cell carcinoma
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to axitinib or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Kidney impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypertension

This medicine should be used with caution in patients suffering from hypertension due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Internal bleeding or hemorrhage

This medicine should be used with caution due to the increased risk of internal bleeding or hemorrhages. Any symptoms such as unusual bleeding or bruising, black or tarry stools, vomiting up blood, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness, tiredness, and visual disturbances. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.

Gastrointestinal Diseases

This medicine should be used with extreme caution in patients suffering from stomach or intestine problems due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atazanavir

Ciprofloxacin

Fluconazole

Carbamazepine

Disease interactions

Cardiac failure

This medicine should be used with extreme caution in patients with cardiac failure due to the increased risk of worsening of the patient's condition. Close monitoring of heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Thyroid disorders

This medicine should be used with extreme caution in patients suffering from thyroid disorders due to the increased risk of worsening of the patient's condition. Close monitoring of thyroid function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Lung impairment

This medicine should be used with caution in patients with a history of interstitial lung disease presenting with acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, and fever pending diagnostic evaluation due to the increased risk of the lung toxicity. Close monitoring of lung function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Avoid consumption of grapefruit or grapefruit juice while taking this medicine since it may cause severe adverse effects. Report to your doctor, if you experience any adverse effects such as high blood pressure, diarrhea, nausea, vomiting, abdominal pain, decreased appetite, weight loss, rash, etc.
Lab interactions
Information not available.
Take this medicine with or without food, as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
This medicine works by inhibiting the actions of certain abnormal proteins that cause the cancer cells to multiply. This helps in stopping the growth and spread of cancer.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antineoplastics, Multikinase inhibitors

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 11 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202324lbl.pdf

[Internet]. Bccancer.bc.ca. 2018 [cited 11 December 2018]. Available from:

http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Axitinib_monograph_1March2014.pdf

[Internet]. Medicines.org.uk. 2018 [cited 11 December 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.7948.pdf

Axitinib - DrugBank [Internet]. Drugbank.ca. 2019 [cited 22 February 2019]. Available from:

https://www.drugbank.ca/drugs/DB06626

Axitinib: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 22 February 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a612017.html

DailyMed - Inlyta- axitinib tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 22 February 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=84137882-e000-47da-bd5b-fa76ab3c76f9
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Information on this page was last updated on 22 Feb 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.