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Indivir 400 mg Capsule

Manufactured byHetero Healthcare Ltd.
ContainsIndinavir
Description

Indivir 400 mg Capsule is an antiviral drug used in the treatment of human immunodeficiency virus (HIV) infection. This medicine will not cure HIV, but it will decrease the chance of developing acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses. Transmitting of HIV infection to other people can be prevented by taking this medicine along with practicing safer sex and other lifestyle changes.

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Side effects

Major & minor side effects for Indivir 400 mg Capsule

  • Nephrolithiasis
  • Hyperbilirubinemia
  • Blood in urine
  • Muscle pain
  • Fever
  • Vomiting blood
  • Loss of appetite
  • Fatigue
  • Skin rash, hives, or itching
  • Weight loss
  • Diarrhea

Uses of Indivir 400 mg Capsule

What is it prescribed for?

  • HIV infection
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for this medicine to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    There is no well-established clinical data available regarding the duration of action of this medicine.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is recommended for use in pregnant women only if necessary. The potential risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is recommended for use in breastfeeding women only in life-threatening conditions. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to indinavir.
Warnings for special population

Pregnancy

This medicine is recommended for use in pregnant women only if necessary. The potential risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is recommended for use in breastfeeding women only in life-threatening conditions. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or discontinue breastfeeding based on your clinical condition.
General warnings

Infections

Use of Indivir 400 mg Capsule may boost the immune response of the body. This may cause the body to fight against latent or chronic infections. Any signs and symptoms of infection should be informed to the doctor immediately. Appropriate treatment should be initiated based on the clinical condition.

Fat redistribution

This medicine may cause fat gain or fat loss from the body. This may cause peripheral wasting, facial wasting, breast enlargement, and Cushingoid appearance. Close monitoring of body weight and body fat distribution is necessary while receiving this medicine. Any abnormal changes in the body should be informed to the doctor on priority.

Diabetes

Indivir 400 mg Capsule may alter the blood glucose levels and may also increase the risk of new-onset diabetes mellitus. Close monitoring of blood glucose levels is necessary while receiving this medicine.

Bleeding disorders

Indivir 400 mg Capsule should be used with caution in patients with bleeding disorders like Hemophilia A or Hemophilia B due to an increase in the risk of excessive bleeding. Report any such symptoms to the doctor on priority. The dose of the medicine should be adjusted based on the clinical condition.

Missed Dose

If a dose of Indivir 400 mg Capsule is missed by more than 2 hours, wait and take the next scheduled dose. Do not double the dose to make up for the missed one. If the dose is missed by less than 2 hours, take the dose as soon as you remember it.

Overdose

Seek emergency medical treatment or contact the doctor immediately in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amiodarone

Hydrocodone

Alprazolam

Atorvastatin

Alfuzosin

Azelastine/fluticasone

Disease interactions

Nephrolithiasis

This medicine should be administered with caution in patients with a known history of kidney stones due to the increased risk of formation of more kidney stones. You are advised to drink plenty of fluids to reduce the risk of dehydration, kidney stones, and other kidney problems. Report any symptoms such as blood in the urine, lower abdominal pain, or any urinary urgency to the doctor on priority. Your doctor may advise you to discontinue the medicine based on your clinical condition.

Liver Disease

This medicine should be used with caution in patients with a known history of liver disease or active liver disease due to the increased risk of adverse effects. Appropriate dose adjustments may be necessary based on the severity of liver disease. Close monitoring of liver functions is advised during treatment with this medicine.
Food interactions
It is recommended to take this medicine on an empty stomach since large amounts of food decrease the absorption of this medicine. It is advised to take this medicine along with a full glass (8 ounces) of water and drink 6 glasses of water every day to prevent the formation of kidney stones. It is advised to avoid eating a high-fat meal before taking this medicine. Your dietitian/doctor may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take Indivir 400 mg Capsule exactly as instructed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that proper hygiene measures are adopted. Complete the course of treatment to prevent the spread of the infection. Close monitoring of liver function and blood glucose levels is necessary while receiving this medicine.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by stopping the human immunodeficiency virus (HIV) from multiplying.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Protease inhibitors

Schedule

Schedule H

Indinavir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 26 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a696028.html

Indinavir - DrugBank [Internet]. Drugbank.ca. 2017 [cited 26 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00224

Indinavir (substance) [Internet]. Snomedbrowser.com. 2017 [cited 26 July 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/372529006

DBGET Search Result: All databases indinavir [Internet]. Genome.jp. 2017 [cited 26 July 2017]. Available from:

http://www.genome.jp/dbget-bin/www_bfind_sub?mode=bfind&max_hit=1000&dbkey=all&keywords=indinavir

DailyMed - CRIXIVAN- indinavir sulfate capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 26 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e19405d9-d9a1-4072-5b9e-40cd3ae4bf1f&audience=consumer

Indinavir FDA Label - Capsule [Internet]. AIDSinfo. 2017 [cited 26 July 2017]. Available from:

https://aidsinfo.nih.gov/drugs/233/indinavir/30/professional
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Information on this page was last updated on 4 Aug 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.