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Indclav (1000/200 mg) Injection

Manufactured byIndchemie Health Specialities Pvt. Ltd.
ContainsAmoxycillin (1000 mg) + Clavulanic Acid (200 mg)
Description
Indclav (1000/200 mg) Injection is an antibiotic containing Amoxicillin and Clavulanic acid. This antibiotic is given as an injection to treat different types of bacterial infections of the throat, lungs, ears, nose, urinary tract, and skin. Indclav (1000/200 mg) Injection is also used with other medications to kill Helicobacter pylori bacteria that cause stomach ulcers. It is not effective against infections caused by viruses or fungus. Indclav (1000/200 mg) Injection use may lead to side effects like diarrhoea, skin rash, pain at the injection site, headache, weakness, and dizziness. Consult your doctor if any of these side effects persist or worsen. Inform your doctor if you are allergic to penicillin or any other antibiotic. Avoid driving vehicles or operating machines if you feel dizzy or sleepy after receiving this medicine. Indclav (1000/200 mg) Injection is injected into a muscle or into a vein. Your doctor will determine how often the injections should be given based on the severity and location of the infection. Once an antibiotic is started, it is always recommended to finish the entire course of treatment. Indclav (1000/200 mg) Injection can be given to both adults and children, but only by a healthcare professional in a hospital setting. Indclav (1000/200 mg) Injection is given only when taking the antibiotic orally is not possible or the infection is severe. Sometimes, this medicine may be followed by oral form (tablets or capsules) of this antibiotic when recovery is seen by an injection. Indclav (1000/200 mg) Injection may not be safe in certain conditions. Inform your doctor if you have/had any medical conditions such as liver, kidney or heart problems and also about other medications being taken before receiving Indclav (1000/200 mg) Injection. Also, inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.

Side effects

Major & minor side effects for Indclav (1000/200 mg) Injection

  • Allergic Skin Reaction
  • Diarrhoea
  • Fever
  • Skin yellowing
  • Easy bruising and bleeding
  • Tooth discoloration
  • Nausea or vomiting
  • Altered sense of taste
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Black or tarry stools
  • Muscle or joint pain
  • Sleeplessness
  • Pain at injection site

Uses of Indclav (1000/200 mg) Injection

What is it prescribed for?

  • Sinusitis
  • Lower Respiratory Tract Infection
  • Acute otitis media
  • Pharyngitis/Tonsilitis
  • Skin Infection
  • Urinary Tract Infection
  • Bone and Joint infections
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Indclav (1000/200 mg) Injection starts working within 1-2 hours of administeration.
  • How long do the effects of this medicine last?
    The effect of Indclav (1000/200 mg) Injection lasts for an average duration of 6-8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Indclav (1000/200 mg) Injection has no habit forming tendencies.
  • Can this medicine be taken during pregnancy?
    Indclav (1000/200 mg) Injection is generally safe in pregnancy to treat bacterial infections. It is not known to cause birth defects when taken by pregnant women. However, it is always better to consult your doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    Indclav (1000/200 mg) Injection is safe to use during breastfeeding. It is not known to be harmful to breastfeeding women. It passes into breast milk in very low levels that are not expected to cause adverse effects in breastfed infants. However, it is always better to consult your doctor before receiving this medicine.

Allergy

Avoid receiving Indclav (1000/200 mg) Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Cholestasis

Indclav (1000/200 mg) Injection should be avoided for use if you have/had cholestasis (a condition where the normal flow of bile from the liver is interrupted)

Liver Disease

Avoid using Indclav (1000/200 mg) Injection if you have a history of liver problems associated with the use of this combination.
Warnings for special population

Pregnancy

Indclav (1000/200 mg) Injection is generally safe in pregnancy to treat bacterial infections. It is not known to cause birth defects when taken by pregnant women. However, it is always better to consult your doctor before receiving this medicine.

Breast-feeding

Indclav (1000/200 mg) Injection is safe to use during breastfeeding. It is not known to be harmful to breastfeeding women. It passes into breast milk in very low levels that are not expected to cause adverse effects in breastfed infants. However, it is always better to consult your doctor before receiving this medicine.
General warnings

Diarrhoea

Indclav (1000/200 mg) Injection can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe diarrhoea that is watery or bloody.

Antibiotic resistance

Finish your entire course of treatment with Indclav (1000/200 mg) Injection, even if the condition gets better to avoid antibiotic resistance (a condition where bacteria develop immunity to overcome the ability of antibiotics to kill them).

Liver disease

Indclav (1000/200 mg) Injection may increase liver enzyme levels and cause liver swelling. If you have liver problems, you need special consideration while taking Indclav (1000/200 mg) Injection due to the risk of liver damage. Your doctor may adjust the dose of this injection and may closely monitor your liver functioning if required, based on your clinical condition.

Form and method of administration

Indclav (1000/200 mg) Injection is generally administered either by slow intravenous injection over a period of 3-4 minutes or by intravenous infusion over a period of 30-40 minutes. It is not suitable for intramuscular administration.

Driving and operating machine

Indclav (1000/200 mg) Injection may cause side effects that could affect your ability to drive. Indclav (1000/200 mg) Injection may cause side effects such as allergic reactions, dizziness or fits that may make you inefficient to drive vehicles or operate machines.

Missed Dose

Since Indclav (1000/200 mg) Injection is given in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since Indclav (1000/200 mg) Injection is given in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Ethinyl Estradiol

Live vaccines

Disease interactions

Mononucleosis

People with mononucleosis (kissing disease) may develop a maculopapular skin rash after 5-10 days of treatment with this medicine that resolves within days of discontinuing the use. Indclav (1000/200 mg) Injection may not be appropriate medicine in people with mononucleosis.

Colitis

Indclav (1000/200 mg) Injection can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Therefore, use this medicine with extreme caution if you have colitis (swelling of the colon's inner lining).

Kidney Diseases

Special consideration is needed while receiving Indclav (1000/200 mg) Injection if you have kidney problems as there is a risk of kidney damage. Dose adjustment will be done by your doctor based on your clinical condition.
Food interactions
Information not available.
Lab interactions

Urine Sugar Test (Benedict's of Fehling's reagent)

High urine concentrations of Indclav (1000/200 mg) Injection might give a false-positive result for the urine glucose test (test to determine the presence of sugar in the urine). Inform your doctor or lab technician about the use of this medicine.
Indclav (1000/200 mg) Injection should be given by a qualified healthcare professional in the clinical or hospital setting. Finish the prescribed course, even if you start feeling better. Stopping it early may lead to a recurrence of the infection and make it difficult to treat. Diarrhoea may occur as a side effect. Taking probiotics (good bacteria that keep you healthy) along with Indclav (1000/200 mg) Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps. Stop taking Indclav (1000/200 mg) Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Indclav (1000/200 mg) Injection is a combination of Amoxycillin and Clavulanic acid. Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].

https://medlineplus.gov/druginfo/meds/a685024.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=909c85de-c076-4444-b63c-cd8bdc556f36>

Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clavulanic-acid>

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>
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Information on this page was last updated on 27 Oct 2021

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