Iloperidone

Description

Iloperidone is an atypical antipsychotic used for the treatment of schizophrenia in adults. Schizophrenia is a brain disorder characterized by delusions, hallucinations, and reduced speaking. This medicine is not recommended for use in children.

Side effects

Major & minor side effects for Iloperidone

  • Irregular heart beat
  • Blurred vision
  • Body pain
  • Cough
  • Fever
  • Headache
  • Dizziness
  • Sweating
  • Back pain
  • Runny Nose
  • Nausea and vomiting
  • Dry skin
  • Shortness of breath

Uses of Iloperidone

What is it prescribed for?

  • Schizophrenia
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to iloperidone or any other inactive ingredients present along with it.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Liver impairment

This medicine should be used with extreme caution in patients suffering from mild to moderate liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe liver impairment.

Renal impairment

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT prolongation

This medicine should be used with extreme caution in patients with a known history of prolonged QT intervals due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Suicidal tendency

This medicine may increase the risk of suicidal thoughts in some patients. Patients should be monitored closely for any changes in behavior or mood. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or operating machinery

This medicine may cause drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Weight gain

This medicine is likely to cause a gain in weight and hence periodic monitoring is required especially in patients who are obese.

Use in elderly population

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Orthostatic hypotension

This medicine is likely to cause position based decrease in blood pressure especially during the start of therapy. It should be given very carefully to patients who have active disease of the heart and valves. Any condition leading to a decrease in blood pressure should be given consideration while deciding the dose.

Alterations in lipid levels

This medicine may cause alterations in lipid levels and should be used with caution in patients with lipid disorders or abnormalities. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Bromocriptine

Alfuzosin

Azithromycin

Citalopram

Clozapine

Chloroquine

Disease interactions

Dementia

This medicine is not recommended for use in patients with dementia-related psychosis due to the increased risk of heart failure, pneumonia, death, etc. This risk is especially high in elderly patients. Replacement with a suitable alternative should be considered under your doctor's supervision.

Neuroleptic Malignant Syndrome (NMS)

This medicine should be used with extreme caution in patients with a known history of a neuroleptic malignant syndrome (NMS) due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Tardive Dyskinesia

This medicine should be used with extreme caution in patients with tardive dyskinesia, a condition of involuntary repetitive body movements, since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate patient/caregiver education, close monitoring of the patient's condition, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypotension

This medicine should be used with caution in patients with hypotension (low blood pressure) due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition. Patients should be advised to get up slowly from a sitting or a lying position to avoid fainting and falling.

Diabetes Mellitus

This medicine should be used with caution in patients with diabetes mellitus because it may alter the blood glucose levels in such patients. Close monitoring of blood glucose levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Seizures

This medicine should be used with caution in patients with seizure disorders or central nervous system abnormalities due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
It works by binding to the receptors and inhibits release of the chemical substances that cause psychotic symptoms.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Iloperidone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 10 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a609026.html

[Internet]. Accessdata.fda.gov. 2018 [cited 10 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022192s017lbl.pdf

Iloperidone - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB04946

DailyMed - Iloperidone- iloperidone tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 10 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=eeb0fcfd-e4e8-4fb1-9635-901dc9446235

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 25 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.