Ibutilide

Description

Ibutilide is an antiarrhythmic medicine that is used to maintain normal heartbeats in patients with a recent episode of atrial flutter or atrial fibrillation (rhythm disorders of the atrium) which may be life-threatening.

Side effects

Major & minor side effects for Ibutilide

  • Dizziness
  • Nausea
  • Headache
  • Pain at the injection site
  • Skin rash

Uses of Ibutilide

What is it prescribed for?

  • Atrial Fibrillation
  • Atrial Flutter
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Concerns

Commonly asked questions

  • Onset of action
    The effect of the medicine can be observed within 90 minutes after the administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to ibutilide or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Electrolyte imbalance

Electrolyte imbalance can alter the therapeutic effectiveness of antiarrhythmic agents. The increase in potassium levels may increase the toxic effects of antiarrhythmic medicines. The baseline of these electrolytes should be obtained before initiation of the therapy and any changes in the values should be reported to the doctor.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Proarrhythmia

This medicine can induce or worsen ventricular arrhythmias in some patients especially those who are suffering from cardiac dysfunction, bradycardia, hypomagnesemia, and hypokalemia. Hence, treatment with this medicine should be reserved for patients with life-threatening arrhythmias.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Efavirenz

Azithromycin

Chloroquine

Venlafaxine

Chlorpromazine

Salbutamol

Disease interactions

Liver impairment

This medicine should be used with extreme caution in patients with liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Cardiovascular diseases

This medicine should be used with caution in patients suffering from cardiovascular disorders such as hypotension (low blood pressure) and CHF (congestive heart failure) Close monitoring of heart function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney impairment

This medicine should be used with extreme caution in patients with kidney impairment due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by reducing the hyperactivity of the heart muscles which helps the heart to beat normally.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Class III antiarrhythmics

Schedule

Schedule H

Ibutilide - DrugBank [Internet]. Drugbank.ca. 2019 [cited 10 December 2019]. Available from:

https://www.drugbank.ca/drugs/DB00308

Ibutilide [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 9 June 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Ibutilide

DailyMed - Ibutilide Fumarate injection, solution [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 9 June 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c25d21e7-6136-4a7a-b139-12f53116fc3d

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Information on this page was last updated on 9 Jun 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.