Hydroxychloroquine

Description

Hydroxychloroquine is an antimalarial medicine which is used in the treatment and suppression of malaria. It is also used in the treatment of Rheumatoid Arthritis and Systemic Lupus Erythematosus. It is not recommended for use in patients with eye diseases. Close monitoring of blood glucose levels and muscle function is necessary while receiving the medicine.

Side effects

Major & minor side effects for Hydroxychloroquine

  • Blurred vision
  • Muscle weakness
  • Ringing or buzzing in the ears
  • Sore throat
  • Diarrhea
  • Headache
  • Loss of appetite
  • Nausea and Vomiting
  • Bleaching of hair
  • Skin rash
  • Nervousness
  • Dizziness

Uses of Hydroxychloroquine

What is it prescribed for?

  • Malaria
  • Systemic Lupus Erythematosus
  • Rheumatoid Arthritis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established. However, it remains in the body for an average duration of 50 days.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless potential benefits outweigh the risks. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is recommended for use in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Hydroxychloroquine or other 4-aminoquinoline compounds.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless potential benefits outweigh the risks. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is recommended for use in breastfeeding women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Effect on heart

Hydroxychloroquine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heartbeats. Close monitoring of heart function is necessary while receiving this medicine. The treatment should be discontinued if any changes in the heart function appear.

Musculoskeletal effects

Hydroxychloroquine may cause muscle weakness if used for a long duration of time. Close monitoring of skeletal muscle function and tendon reflexes is necessary while receiving this medicine. The treatment should be discontinued if symptoms of muscle weakness appear.

Effect on kidney

Hydroxychloroquine should be used with caution in patients with kidney disease. Close monitoring of kidney function is necessary while receiving this medicine. The dose should be adjusted based on the creatinine clearance.

Effect on liver

Hydroxychloroquine should be used with caution in patients with liver diseases and alcoholic patients. Inform the doctor about any history of liver disease before taking this medicine. Close monitoring of liver function is necessary while receiving this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Thioridazine

Aluminium Hydroxide/Magnesium Hydroxide

Antidiabetic medicines

Atorvastatin

Disease interactions

Oculotoxicity

This medicine is not recommended for use in patients with a history of eye diseases. Close monitoring of eye function is necessary while receiving this medicine. The treatment should be discontinued if symptoms of visual changes appear.

Porphyria

This medicine is not recommended for use in patients with Porphyria which is a rare genetic disorder. Inform the doctor if you have a history of any genetic disorder. An alternate treatment option should be considered based on the clinical condition.

Blood disorders

This medicine should be used with caution in patients with a history of blood disorders. Close monitoring of white blood cell count, hemoglobin, and platelets is necessary while receiving this medicine. The treatment should be discontinued if the blood cell count reduces.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Hydroxychloroquine as advised by the doctor. Do not consume larger quantities than prescribed. Close monitoring of blood glucose levels is necessary while receiving this medicine. Contact the doctor immediately if the symptoms are not reduced or worsen. The treatment should be discontinued if any undesired effect appears.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
It works as an antimalarial by blocking the growth of the malaria parasite. It is also used in the treatment of autoimmune diseases like Rheumatoid Arthritis and Systemic Lupus Erythematosus by blocking the release of chemical substances that cause inflammation.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antimalarial Quinolines, Antirheumatics

Schedule

Schedule H

[Internet]. 2017 [cited 19 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/22795

DailyMed - Hydroxychloroquine sulfate tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9d22f0a8-170b-4c3e-8c2e-a5cf64b9958b

Hydroxychloroquine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01611

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 19 July 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 19 July 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~L1Z87W:1

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Information on this page was last updated on 5 Jan 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.