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Hydrolin 100 mg Injection
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Hydrolin 100 mg Injection

Manufactured byHetero Healthcare Ltd.
ContainsHydrocortisone
Description
Hydrolin 100 mg Injection is used to treat the deficiency of steroidal hormones in the body. It is also used to manage an acute episode of asthma. This medicine is used to relieve swelling and inflammation of joints and soft tissues associated with arthritis.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Hydrolin 100 mg Injection

Alcort 100 mg Injection
Alembic Ltd.
Cortgee 100 mg Injection
Zydus Cadila
Efcorlin 100 mg Injection
Glaxosmithkline Pharmaceuticals Ltd.
Stecort 100 mg Injection
Ranbaxy Laboratories Ltd.
Cortisum 100 mg Injection
Unichem Laboratories Ltd.

Side effects

Major & minor side effects for Hydrolin 100 mg Injection

  • Headache
  • Dizziness
  • Delayed wound healing
  • Sleeplessness
  • Extreme changes in mood
  • Sore throat and fever
  • Weight gain
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Difficulty in breathing
  • Irregular menstrual periods
  • Blurred vision
  • Muscle weakness
  • Black or tarry stools
  • Injection site pain

Uses of Hydrolin 100 mg Injection

What is it prescribed for?

  • Adrenal insufficiency
  • Acute asthma
  • Swelling and pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to hydrocortisone or any other ingredients present along with the formulation.

Untreated serious infection

This medicine is not recommended for use if you have an active infection which is untreated or the treatment is in progress.

Idiopathic thrombocytopenic purpura

This medicine is not recommended for use if you have this immune system disorder that causes a decrease in the level of blood cells.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Other diseases

Report the incidence of any active disease to the doctor before receiving this medicine. Chances of any interaction while consuming this medicine must be ruled out. Special caution is advised in cases of heart conditions, liver problems, infections, diabetes, and psychotic disorders.

Delayed wound healing

Use of this medicine may delay the process of wound healing. Your doctor may determine the best course of treatment in such cases based on your clinical condition.

Vaccination

Administration of live or attenuated vaccines is not recommended in patients receiving immunosuppressive doses of this medicine due to the increased risk of serious adverse effects. Your doctor may advise you on an appropriate time gap between the administration of the vaccine and the medicine or suggest an alternative medicine or alternative means of vaccination based on your clinical condition.

Tuberculosis relapse

Use of this medicine may cause a recurrence of tuberculosis and hence, this medicine should not be used if the patient has tested positive for the tuberculin test.

Driving or operating machinery

This medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during or immediately after treatment with this medicine.

Pheochromocytoma

This medicine should not be used in patients having a disorder of the adrenal glands. Appropriate tests must be performed to rule out this condition before treatment is initiated.

Withdrawal

Abrupt withdrawal of this medicine may cause unwanted side effects. It is advised to gradually reduce the dosage of this medicine before stopping the treatment.

Use in children

Prolonged use of this medicine in infants and children should be avoided as it may alter their growth and development process. Appropriate dose adjustments are to be made since the amount of medicine absorbed into the body of an infant and children is significantly higher than that of adults.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Epidural injection

The epidural route of administration for this medicine should be avoided as the safety and efficacy are not established. Some serious adverse effects have been reported with the epidural administration method.

Psychiatric disturbances

Use of this medicine has been associated with euphoria, sleep disturbances, mood swings, and personality changes in some patients. It is advised to consider all such disorders before starting the treatment course with this medicine. Appropriate dose adjustments may be required if the patient is under stress.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amlodipine

Carbamazepine

Estradiol

Metformin

Phenytoin

Warfarin

Phenobarbital

Live attenuated vaccines and related products

Diclofenac

Disease interactions

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of a rise in blood glucose levels. Close monitoring of glucose levels is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperadrenocorticism

This medicine is not recommended for use in patients having a condition where the adrenal glands secrete an excess of steroidal hormones in the body. Suitable tests must be conducted to rule out this condition before beginning treatment with this medicine.

Infections

This medicine should be used with extreme caution in patients with latent or active infections since this medicine can suppress the immune system and worsen the patient's condition. This risk is especially higher in patients on high doses of this medicine for a prolonged period of time. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Myocardial infarction

This medicine should be used with extreme caution in patients with a history of myocardial infarction due to an increase in the risk of worsening of the patient's condition. Close monitoring of heart function and vital signs is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperlipidemia

This medicine should be used with caution in patients with preexisting hyperlipidemia due to an increased risk of elevation in serum triglycerides and LDL cholesterol levels. Close monitoring of triglycerides and cholesterol levels is recommended for these patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Osteoporosis

This medicine should be used with caution in patients with osteoporosis due to an increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Gastrointestinal perforation

This medicine is known to cause perforations and bleeding in the gut especially when high doses are consumed. Hence this medicine should be administered with caution in patients having a pre-existing perforation disorder of the stomach or intestine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Electrolyte imbalance

This medicine should be used with caution in patients with preexisting electrolyte imbalance due to the increased risk of worsening of the patient's condition. Regular monitoring of electrolyte levels is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by reducing the action of certain chemicals that cause swelling and pain in the body. It also changes the way in which the immune system normally works.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Glucocorticoids

Schedule

Schedule H

Hydrocortisone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 12 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00741

Hydrocortisone | C21H30O5 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 12 July 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/5754

Hydrocortisone 100mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2019 [cited 23 October 2019]. Available from:

https://www.medicines.org.uk/emc/product/7812

[Internet]. Accessdata.fda.gov. 2019 [cited 30 September 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/009866s080lbl.pdf
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Information on this page was last updated on 24 Oct 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.