Human Rabies Immunoglobulin

Description

Human Rabies Immunoglobulin is a human-derived rabies vaccine that is used to protect against rabies infection. It is given if you are suspected of exposure to rabies after an animal bite if the animal could have rabies. Human Rabies Immunoglobulin is also given if you are at high risk of coming in contact with rabies-like veterinarians. This vaccine partially suppresses the active production of antibodies and prevents the rabies virus from spreading across your body. Human Rabies Immunoglobulin has some common side effects such as joint pain, muscle pain and redness of the site of injection and swelling. These side effects are self-limiting. Consult your doctor if any of these side effects do not resolve with time or get worse. Inform your doctor if you have been allergic to any vaccine. Human Rabies Immunoglobulin is given immediately after exposure to rabies or within seven days of bite or scratch by the animal infected with rabies. It is not recommended for individuals who have already received a rabies vaccine as it is given only once in a lifetime. If the vaccine is given immediately and appropriately, it is highly effective. Human Rabies Immunoglobulin is given after washing thoroughly (with soap and sufficient amounts of water for a few minutes) of all bitten wounds as early as possible. It should only be given by a specialized healthcare professional under proper supervision. Human Rabies Immunoglobulin is advised to be given after you share your entire medical and medication history with your doctor. Let the doctor know if you are pregnant, planning a pregnancy or are breastfeeding.

Side effects

Major & minor side effects for Human Rabies Immunoglobulin

  • Difficulty in breathing
  • Dizziness
  • Cough
  • Body aches or Pain
  • Headache
  • Sneezing
  • Numbness of hands or feet
  • Unusual tiredness or weakness
  • Fever or chills
  • Skin rash
  • Loss of voice

Uses of Human Rabies Immunoglobulin

What is it prescribed for?

  • Rabies Prophylaxis
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of Human Rabies Immunoglobulin can be observed immediately after the administration of the dose.
  • Duration of effect
    The amount of time for which Human Rabies Immunoglobulin remains active in your body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    Human Rabies Immunoglobulin has no habit-forming tendency.
  • Usage in pregnancy?
    Human Rabies Immunoglobulin is not recommended for use in pregnant women unless absolutely necessary. Your doctor will decide whether it is safe for you or not. Discuss the potential benefits and risks before receiving this vaccine.
  • Usage while breast-feeding?
    Human Rabies Immunoglobulin is not recommended for use in breastfeeding women unless absolutely necessary. Discuss the potential benefits and risks before receiving this vaccine.
Warnings for special population

Pregnancy

Human Rabies Immunoglobulin is not recommended for use in pregnant women unless absolutely necessary. Your doctor will decide whether it is safe for you or not. Discuss the potential benefits and risks before receiving this vaccine.

Breast-feeding

Human Rabies Immunoglobulin is not recommended for use in breastfeeding women unless absolutely necessary. Discuss the potential benefits and risks before receiving this vaccine.
General warnings

Severe allergic reactions

Human Rabies Immunoglobulin is not recommended to be injected into a blood vessel due to the risk of severe allergic or hypersensitivity reactions, including anaphylactic shock (severe allergy), low blood pressure, etc.

Thrombosis

Human Rabies Immunoglobulin may cause thrombosis (formation of a blood clot within a blood vessel). Appropriate measures should be taken based on your clinical condition.

Hemolysis

Human Rabies Immunoglobulin may cause the destruction of red blood cells. Report any unusual symptoms such as fever, chills, or dark urine to your doctor immediately.

Serologic testing

Human Rabies Immunoglobulin may interfere with serologic testing (blood test to know if a person is exposed to microorganisms) causing a short time rise of the various passively transferred antibodies in your blood, which may give false-positive results.

Missed Dose

As Human Rabies Immunoglobulin is given in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since Human Rabies Immunoglobulin is given in the hospital or clinical setting by a qualified healthcare professional, the chance of an overdose is low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live attenuated vaccines and related products

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Human Rabies Immunoglobulin is given as an injection into the area around or into the wounds. The remaining contents are given on your muscle of the upper arm. Human Rabies Immunoglobulin should be given by specialized healthcare professionals under proper supervision.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Human Rabies Immunoglobulin partially suppresses the active production of antibodies and prevents the rabies virus from spreading across your body.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Immune globulins

Schedule

Schedule C

Medicines.org.uk. 2021. Human Rabies Immunoglobulin - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 25 August 2021].

https://www.medicines.org.uk/emc/product/5543>

Dailymed.nlm.nih.gov. 2021. DailyMed - KEDRAB- human rabies virus immune globulin injection, solution. [online] Available at: < [Accessed 25 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=53f2a23b-c479-4c24-8cab-ee7a33a2633e>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 25 August 2021].

https://www.medicines.org.uk/emc/files/pil.5543.pdf>

How will this medicine affect me?

Consult top doctors online and get an answer now
Consult now
Consult now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 31 Aug 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.