Human Albumin

Description

Human albumin, the major ingredient of Human Albumin, is a major protein found in the blood. It helps in maintaining the colloid osmotic pressure as well as in transportation of various components in the blood. As a medicine, it is used to maintain blood volume in cases of blood loss due to severe burns, injuries, surgeries, etc.

Side effects

Major & minor side effects for Human Albumin

  • Fever and chills
  • Edema
  • Itching
  • Nausea and Vomiting
  • Headache
  • Low blood pressure
  • Difficulty in breathing
  • Severe allergic reaction

Uses of Human Albumin

What is it prescribed for?

  • Hypovolemia
  • Cardiopulmonary Bypass Procedure
  • Hypoalbuminemia
  • Plasma Exchange
  • Adult Respiratory Distress Syndrome
  • Paracentesis
  • Hemolytic Disease of the Newborn (HDN)
  • Acute Nephrosis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 15 minutes of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the appropriate course after evaluating all the risks and benefits associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the appropriate course after evaluating all the risks and benefits associated with the use of this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.

Allergy

This medicine is not recommended for use in patients with a known allergy to human albumin or any other inactive ingredients present along with it.

Cardiac failure

This medicine is not recommended for use in patients suffering from a cardiac failure since it may worsen the patient's condition.

Severe anemia

This medicine is not recommended for use in patients suffering from severe anemia since it may worsen the patient's condition.

Hypertension

This medicine is not recommended for use in patients suffering from hypertension (high blood pressure) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the appropriate course after evaluating all the risks and benefits associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the appropriate course after evaluating all the risks and benefits associated with the use of this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is necessary.
General warnings

Hypersensitivity reactions

Severe hypersensitivity reactions have been reported with this medicine, which may progress to severe anaphylaxis. In such cases, immediate discontinuation of the therapy is required.

Hypervolemia/Hemodilution

Hypervolemia may occur if the dosage and rate of infusion are not adjusted to the patient’s volume status. This might be presented with symptoms such as a headache, difficulties with breathing, increased blood pressure, jugular venous distention, elevated central venous pressure, pulmonary edema, etc. The infusion should be stopped immediately and the patient's clinical condition should be reevaluated in such cases. Human Albumin should be used with extreme caution in conditions where hypervolemia and its consequences or hemodilution could represent a significant risk for the patient.

Coagulation abnormalities

Monitoring of coagulation parameters and hematocrit are necessary if comparatively large volumes are to be replaced. Care must be taken to ensure adequate substitution of other blood constituents (coagulation factors, electrolytes, platelets, and erythrocytes) along with Human Albumin to reduce the risk of significant adverse effects.

Electrolyte imbalances

Regular monitoring of electrolyte status may be required during the administration of this medicine due to the increased risk of electrolyte imbalances. Appropriate corrective or preventive measures may be necessary in some cases based on the patient's clinical condition.

Clinical monitoring

It is recommended to monitor the hemodynamic status of the patient while administering this medicine. Values such as arterial blood pressure, pulse rate, central venous pressure, pulmonary artery occlusion pressure, urine output, etc. should be monitored closely during and post administration of this medicine based on the clinical condition of the patient.

Missed Dose

Since this medicine is administered by a qualified health care professional in the hospital/clinical setting, the likelihood of missing a dose is very low.

Overdose

Since this medicine is administered in the hospital/clinical setting by a qualified health care professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine will be administered by a qualified health care professional in the clinical/hospital setting. Inform the doctor if you have a known allergy to this medicine. Follow all the instructions given by your doctor. Report all your current medicines as well as your medical conditions to the doctor before receiving therapy with this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
It increases the levels of albumin in the blood and helps in maintaining the blood volume.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Plasma expanders

Schedule

Schedule H

[Internet]. 2018 [cited 31 May 2018]. Available from:

https://www.glowm.com/resources/glowm/cd/pages/drugs/a011.html

Human Albumin Biotest 20% - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 31 May 2018]. Available from:

https://www.medicines.org.uk/emc/product/577/smpc#INTERACTIONS

DailyMed - Albumin human solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 31 May 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a912d27c-00cb-2ed0-effe-2d88d1f2ca67

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Information on this page was last updated on 2 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.