Homatropine hydrobromide

Description

Homatropine hydrobromide is a medicine used to widen the pupil before an eye exam or eye surgery. It is also used to treat uveitis, a condition where the middle layer of the eye (uvea) is swollen and red.

Side effects

Major & minor side effects for Homatropine hydrobromide

  • Transient burning sensation of the eyes
  • Transient stinging sensation of the eyes
  • Increased sensitivity of the eyes to light
  • Local irritation
  • Redness in and around the eyes
  • Swelling around the eyes
  • Increased thirst
  • Dryness of mouth
  • Discharge from eyes

Uses of Homatropine hydrobromide

What is it prescribed for?

  • Refraction
  • Uveitis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 10-90 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 10 to 48 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to homatropine hydrobromide or any other inactive ingredients present in the formulation.

Glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma or primary glaucoma due to the increased risk of worsening of the patient’s condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Other medicines

Homatropine hydrobromide may interact with many other ophthalmic medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Glaucoma

Report to your doctor about personal or family history of glaucoma before the treatment with this medicine is initiated. The risk of adverse events and worsening of glaucoma symptoms is significantly high upon using this medicine.

Driving or Operating machinery

Use of this medicine may cause blurred vision in some patients. If you experience blurred vision during treatment with this medicine, it is advised that you do not perform any activities such as driving a vehicle or operating machinery until your vision is clear.

Photosensitivity of eyes

Use of this medicine may make your eyes more sensitive to light. It is advised to protect your eyes from bright lights and use appropriate precautionary measures while going outdoors at daytime.

Use in elderly

This medicine should be used with caution in the elderly patients since the likelihood of severe adverse effects is significantly high.

Use in children

This medicine is not recommended for use in infants less than 3 months of age since the safety and efficacy of use are not clinically established. It should be used with caution in children less than 12 years of age and only under the supervision of your pediatrician.

Belladonna poisoning

Use of this medicine in excess in pediatric patients and in certain individuals with a history of susceptibility to belladonna alkaloids (atropine, hyoscyamine, scopolamine, etc.) may cause systemic symptoms of homatropine poisoning. Appropriate precautions should be taken to prevent swallowing of the medicine to reduce this risk.

Down's syndrome

This medicine should be used with caution in patients with Down’s syndrome due to the increased risk of angle closure glaucoma. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Keratoconus

This medicine should be used with caution in patients with keratoconus (a condition where the cornea gets thin and bulges outside of the eye) due to the increased risk of fixed pupillary dilation. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

For Refraction: Since this medicine is usually given prior to eye procedures, the likelihood of missing a dose is very low. For Uveitis: Administer the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

For Refraction: Since this medicine is administered in the clinic or hospital setting under the supervision of a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. For Uveitis: Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Phenylephrine

Pilocarpine (Ophthalmic)

Carbachol (Ophthalmic)

Acetylcholine

Demecarium bromide (Ophthalmic)

Isoflurophate (Ophthalmic)

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
If this medicine is used for refraction, it is usually administered in a hospital setting by a qualified healthcare professional. For uveitis, use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by widening the pupil of the eye.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Mydriatics

Schedule

Schedule H

DailyMed - Homatropine hydrobromide ophthalmic solution [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 30 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=538ef499-28cb-a4d1-5f16-6e87ac4e07ac

Homatropine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 30 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB11181

Homatropine - an overview | ScienceDirect Topics [Internet]. Sciencedirect.com. 2018 [cited 20 December 2018]. Available from:

https://www.sciencedirect.com/topics/neuroscience/homatropine

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Information on this page was last updated on 3 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.