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Histamet Tablet
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Histamet Tablet

Manufactured bySYMET DRUGS LTD
ContainsParacetamol (500 mg) + Caffeine (30 mg) + Chlorpheniramine (4 mg)
Description
Histamet Tablet is a combination of Paracetamol, Caffeine and Chlorpheniramine Maleate. It is used to treat symptoms of allergy and common cold such as runny nose, fever, sneezing, cough, itchy and watery eyes, headache, fever, etc. This medicine works by blocking the action of certain chemicals (prostaglandins and histamine) and provides relief from common cold symptoms, pain, and fever. Histamet Tablet shows side effects like nausea, vomiting, sleepiness, restlessness etc. Most of these are temporary and get resolved with time. Consult your doctor if these side effects bother you. Avoid performing any activity that requires mental focus like driving or operating machines as this medicine can make you sleepy. Histamet Tablet can be taken with or without food as prescribed by your doctor. Complete the whole course to see maximum benefits. Do not stop taking this medicine without consulting your doctor as your symptoms may reappear. Take this medicine around the same time every day so that a constant level of medicine can be maintained in your body. Histamet Tablet should be avoided if you are allergic to it. Inform your doctor if you have severe liver, kidney, or heart problems. Also, inform your doctor if you are taking any other medicines, herbs, or supplements as they may interact with Histamet Tablet. Histamet Tablet is not recommended in children below the age of 2 years. Consult your doctor if you are pregnant, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Histamet Tablet

  • Nausea and vomiting
  • Skin rash
  • Dark or clay colored stools
  • Tiredness
  • Loose stools
  • Bloody and cloudy urine
  • Stomach discomfort
  • Sleepiness or unusual drowsiness
  • Blurred or double vision
  • Dry mouth

Uses of Histamet Tablet

What is it prescribed for?

  • Common Cold
  • Allergic Rhinitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Histamet Tablet can be seen within 30-60 minutes after administration.
  • How long do the effects of this medicine last?
    It is not known how long Histamet Tablet remains active in your body.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid the consumption of alcohol or limit its use while taking Histamet Tablet as it may increase the risk of serious side effects that affect your liver. Other side effects include drowsiness, dizziness, and difficulty concentrating. Hence, avoid performing activities that need high mental alertness like driving vehicles or operating machines.
  • Is this a habit forming medicine?
    No habit-forming tendency has been found with the use of Histamet Tablet.
  • Can this medicine be taken during pregnancy?
    Histamet Tablet is generally not recommended for use in pregnant women as not enough studies are done to understand its safety. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Histamet Tablet is not recommended in breastfeeding women as it is not known if this medicine passes into breast milk or not. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Histamet Tablet if you are allergic to it. It may lead to symptoms such as shortness of breath, swelling of the face, lips, tongue, or other parts of your body, rash, itching or hives on your skin, etc. Ask for another suitable medicine in such cases
Warnings for special population

Pregnancy

Histamet Tablet is generally not recommended for use in pregnant women as not enough studies are done to understand its safety. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks. Consult your doctor if you are pregnant.

Breast-feeding

Histamet Tablet is not recommended in breastfeeding women as it is not known if this medicine passes into breast milk or not. Consult your doctor if you are breastfeeding.
General warnings

Chronic malnutrition

Proper nutrition and body weight are required for proper use Histamet Tablet. Malnutrition and fasting can increase the risk of toxicity. Dose adjustment should be done based on body weight.

Epilepsy

Epilepsy/Seizures is a disorder in which brain activity becomes abnormal leading to abnormal jerking of the body. Use Histamet Tablet with caution if you have epilepsy since it increases the risk of seizures. Your doctor may adjust the dose or suggest another suitable medicine if required.

Driving or operating machines

Avoid performing activities that require high mental alertness like driving vehicles or operating machines while taking Histamet Tablet as it increases the risk of drowsiness, dizziness, and difficulty in concentration.

Kidney impairment

Histamet Tablet is excreted by your kidneys. Hence, use this medicine with caution if you have severe kidney impairment as it may increase the accumulation of this medicine in your body. It may increase the risk of side effects. Your doctor may adjust the dose or suggest another suitable medicine if required.

Missed Dose

If you forget to take Histamet Tablet, take it as soon as you remember. If it is time for the next dosage then skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. In case of an overdose, seek immediate medical attention or consult your doctor.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid the consumption of alcohol or limit its use while taking Histamet Tablet as it may increase the risk of serious side effects that affect your liver. Other side effects include drowsiness, dizziness, and difficulty concentrating. Hence, avoid performing activities that need high mental alertness like driving vehicles or operating machines.
Interaction with Medicine

Sodium Nitrite

Leflunomide

Prilocaine

Anxiolytics

Phenytoin

Carbamazepine

Disease interactions

Alcoholism

If a person has a habit of drinking too much alcohol (alcoholism), then use of Histamet Tablet may increase the risk of liver damage. Alcohol consumption should be discontinued while taking this medicine.

Liver Disease

Histamet Tablet is mainly broken down in your liver. This medicine should be used with caution if you have liver problems as it increases the risk of liver toxicity. Your doctor may closely monitor your liver function while you are taking this medicine.

Asthma

Use Histamet Tablet with caution if you have asthma (a condition in which your airways become narrow and may also produce extra mucous). This medicine can increase the production of mucous and obstruct the respiratory tract. Consult your doctor if you have any concerns.

Cardiovascular disease

Histamet Tablet may infrequently lead to cardiovascular side effects such as an increase in heart rate, irregular heartbeat, altered blood pressure, etc. Use this medicine with caution if you have cardiovascular diseases. Consult your doctor if you have any concerns.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Histamet Tablet can interfere with the urine test and may give a false test result. Inform your doctor and/or lab technician about all your current medications before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Histamet Tablet with or without food as prescribed by your doctor. Do not crush, break or chew the tablet. Never take more or less than the prescribed dose of this medicine. Complete the course of treatment. Avoid discontinuation of this medicine without consulting your doctor. Consult your doctor if your symptoms have not improved within seven days of treatment.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Histamet Tablet is a combination of three medicines: Paracetamol, Caffeine, and Chlorpheniramine Maleate which relieve common cold symptoms. Paracetamol is an analgesic (pain killer) and antipyretic (fever reducer). It blocks the release of prostaglandins that are responsible for pain and fever. Caffeine increases the effectiveness of Paracetamol. Chlorpheniramine is an antiallergic medicine that relieves allergy symptoms like runny nose, watery eyes, and sneezing.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, CNS stimulants, Anti-allergic agent

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Acetaminophen. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top>

Medicines.org.uk. 2021. Paracetamol 500mg Soluble Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 10 August 2021].

https://www.medicines.org.uk/emc/product/4199/smpc#gref>

Medicines.org.uk. 2021. Boots Allergy Relief 4 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 10 August 2021].

https://www.medicines.org.uk/emc/product/2887/smpc>

Pubchem.ncbi.nlm.nih.gov. 2021. Caffeine. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/2519>
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Information on this page was last updated on 17 Jan 2022

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