Histafree-M Tablet

Manufactured byMankind Pharmaceuticals Ltd.
ContainsMontelukast (10 mg) + Fexofenadine (120 mg)
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Valid on prescription medicines, only for first time user
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Description

Histafree-M Tablet is a combination medicine used to relieve the symptoms of allergic rhinitis. This medicine is not recommended for use in patients less than 15 years of age.

Substitutes

List of substitutes for Histafree-M Tablet

Side effects

Major & minor side effects for Histafree-M Tablet

  • Headache
  • Stomach pain
  • Chest tightness
  • Joint pain
  • Difficulty in swallowing
  • Pus in urine
  • Agitation and anxiety
  • Skin rash
  • Influenza
  • Infection of the airways
  • Churg-Strauss syndrome
  • Suicidal thinking and behaviour
  • Dizziness
  • Vomiting
  • Coughing
  • Diarrhea
  • Painful menstruation
  • Difficulty in breathing

Uses of Histafree-M Tablet

What is it prescribed for?

  • Allergic rhinitis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1-2 hours of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of liver injuries.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to montelukast, fexofenadine, or any other inactive ingredient present along with these medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Systemic Eosinophilia

This medicine is not recommended for use in patients with a known history of systemic eosinophilia due to the increased risk of worsening of the patient's condition.

Behaviour and mood changes

This medicine may cause changes in behavior and mood in some patients. Symptoms such as agitation, irritability, anxiety, unusual dreams, suicidal thoughts, etc. should be reported to the doctor on priority. This risk is especially higher in patients with a history of psychiatric disorders. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Pediatric Use

This medicine is not recommended for use in patients less than 15 years of age since the safety and efficacy of use are not clinically established.

Liver impairment

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients with a known history of renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or Operating machinery

This medicine may rarely cause symptoms such as drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of liver injuries.
Interaction with Medicine

Ketoconazole

Rifampicin

Phenobarbital

Antacids

Erythromycin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with a known history of liver function impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Impaired kidney function

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Do not consume large quantities of juices of fruits such as grapefruit, orange, apple, etc. since these juices may reduce the effectiveness of this medicine.
Lab interactions

Skin allergy test

Report the use of this medicine before undergoing a skin allergy test. This medicine may interfere with the results of this test and hence, your doctor may advise you to discontinue the use of this medicine at least 2 to 4 days before undergoing this test.
Take this medicine as instructed by the doctor. Follow all the uptake instructions mentioned on the label. This medicine can be taken with or without food. The quantity consumed should not be higher than the prescribed dose. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Montelukast acts by blocking the response of certain specific chemicals that cause allergic reactions in the body. Fexofenadine reduces the concentration of histamine, a substance responsible for causing allergic responses in the body. Their combination is thus better effective for the treatment of allergic rhinitis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Leukotriene modifiers, Antihistamines

Schedule

Schedule H

[Internet]. Centaurpharma.com. 2018 [cited 14 March 2018]. Available from:

http://www.centaurpharma.com/newwebsite/downloads/MTFx_Tablet.PDF

[Internet]. CiplaMed. 2018 [cited 14 March 2018]. Available from:

https://ciplamed.com/content/montair-fx-tablets

[Internet]. 2017 [cited 23 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28220
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