1. Home >
  2. Medicine Info >
  3. Herpesafe 400 MG Tablet DT

Herpesafe 400 MG Tablet DT

Manufactured by: Alkem Laboratories Ltd.
Composition: Aciclovir
Prescription Required: Yes
More
    Contents

Description

Herpesafe 400 MG Tablet DT is an antiviral agent which is used in the treatment of infections caused by herpes virus such as chickenpox and herpes zoster. The effect of this medicine is higher if it is started as soon as symptoms appear.

Side effects

Major & minor side effects for Herpesafe 400 MG Tablet DT

  • Swelling and redness at the injection sitesevere
  • Abdominal painsevere
  • Increased thirstsevere
  • Loss of appetitesevere
  • Unusual tiredness and weaknesssevere
  • Black or tarry stoolssevererare
  • Fever with chillssevererare
  • Seizuressevererare
  • Unusual bleedingsevererare
  • Diarrhea
  • Headache
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Herpesafe 400 MG Tablet DT

Onset of action

The peak effect of this medicine can be observed in 1.5 to 2 hours after an oral dose and 2 hours after an intravenous dose.

Duration of effect

The effect of this medicine lasts for an average duration of 9 to 12 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit tendencies have been reported.

Usage in pregnancy?

This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.

Usage while breast-feeding?

This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

Substitutes

List of substitutes for Herpesafe 400 MG Tablet DT

Below is the list of medicines, which have the same composition, strength and form as Herpesafe 400 MG Tablet DT, and hence can be used as its substitute.
Acivir 400 MG Tablet DT
Cipla Ltd.
Ocuvir 400 MG Tablet DT
Fdc Ltd.

What is it prescribed for?

Uses of Herpesafe 400 MG Tablet DT

  • Herpes Zoster Infections

    Herpesafe 400 MG Tablet DT is used in the treatment of herpes zoster infection which is a viral infection caused by varicella-zoster virus.
  • Genital Herpes

    Herpesafe 400 MG Tablet DT is used in the treatment of genital herpes which is a sexually transmitted viral infection caused by herpes simplex virus.
  • Chickenpox

    Herpesafe 400 MG Tablet DT is used in the treatment of chicken pox which is a viral infection caused by varicella-zoster virus.

Find a doctor near you

Looking for a doctor?

Book an appointment with the top doctors near you.

When not to use?

Contraindications of Herpesafe 400 MG Tablet DT

  • Allergy

    If you have a known allergy to Herpesafe 400 MG Tablet DT or any other medicine belongs to the class anti-herpes virals.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Phenytoinmoderate
  • Tacrolimussevere
  • Sulfasalazinemoderate

Disease interactions

  • Impaired kidney function

    severe
    Herpesafe 400 MG Tablet DT should be used with caution in the patients with the pre-existing kidney injury. Inform the doctor if you experience any symptoms of sudden weight gain, changes in the frequency of urination. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
  • Neurological disorder

    moderate
    Use of high-dose intravenous Herpesafe 400 MG Tablet DT may increase the risk of neurotoxicity, especially in the elderly population with a neurological disorder, kidney or liver injury. Inform the doctor if you experience any symptoms of tremors, confusion, and seizures. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Herpesafe 400 MG Tablet DT with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor. Drink adequate amount of water in order to reduce the risk of kidney injury.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is recommended for pregnant women. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine.
  • Breast-feeding

    - This medicine is excreted through the breastmilk. Discuss with your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of any undesired effects is necessary.

General warnings

  • Hydration

    - Herpesafe 400 MG Tablet DT may increase the risk of kidney injury when taken with other medicines that cause kidney injury. Adequate water should be consumed to prevent the accumulation of the medicine.
  • Impaired kidney function

    - Herpesafe 400 MG Tablet DT is used with caution in the patients with the severe kidney injury. Suitable dose adjustments are to be made based on the clinical condition.
  • Elderly population

    - Herpesafe 400 MG Tablet DT is used with caution in the elderly population with kidney injury or liver injury due to increase in the risk of neurological problems. Dose adjustments are to be made based on the clinical condition.
  • Pediatric population

    - The safety and efficacy of the oral formulation of Herpesafe 400 MG Tablet DT has not been established in children less than 2 years of age.

Other details

  • Food timings: Information not available
  • Administration time: Information not available
  • Sleep inducing: Information not available

How it works

It works by inhibiting the viral DNA synthesis and replication by inhibiting the DNA polymerase enzyme.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Antiviral agents
Schedule
Schedule H

References

  • Acyclovir Uses, Dosage & Side Effects - Drugs.com [Internet]. Drugs.com. 2017 [cited 22 March 2017]. Available from: https://www.drugs.com/acyclovir.html
  • [Internet]. 2017 [cited 22 March 2017]. Available from: https://www.medicines.org.uk/emc/medicine/32808
  • DailyMed - ACYCLOVIR- acyclovir capsule ACYCLOVIR- acyclovir tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 22 March 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d13b8cdd-59fd-472b-8125-a19f42ef5402
  • Zovirax (acyclovir) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 22 March 2017]. Available from: http://reference.medscape.com/drug/zovirax-acyclovir-342601
  • Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 22 March 2017]. Available from: https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname
  • TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 22 March 2017]. Available from: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~5GaPoc:1

Chat with a doctor

Get reply within 5 mins

How will this medicine affect me?

Chat with verified doctors starting @ ₹99

Did you find this helpful?

Your feedback will help us improve the product

Thanks for your response
What can we improve?
Thanks for your response
Information on this page was last updated on 7 Aug 2017

Report an error

Oops! Seems like there is an error in your form. Make sure -
  1. Your email ID is correct.
  2. Your response is not blank.
  3. Your internet is working.
Thank you!
Your response is valuable to us.

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.