Goserelin

Description

Goserelin is an anticancer drug used in the treatment of advanced prostate cancer. It is used along with radiation therapy for the treatment of localized prostate cancer. In women, this medicine can be used for palliative treatment of advanced breast cancer, abnormal uterine bleeding, and endometriosis, a condition characterized by abnormal growth of uterine tissue, severe pain, and heavy or irregular periods.

Side effects

Major & minor side effects for Goserelin

  • Hypersensitivity
  • Fast/irregular heart beat
  • Trouble breathing
  • Breast pain and tenderness
  • Increase in blood glucose level
  • Bone and joint pain
  • Unusual sweating
  • Unwanted hair growth
  • Anxiety

Uses of Goserelin

What is it prescribed for?

  • Prostate cancer
  • Endometriosis
  • Palliative treatment of breast cancer
  • Abnormal uterine bleeding
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to goserelin or any other components present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Diabetes

Goserelin may cause an increase in the blood glucose levels or may increase the chances of development of diabetes. It may also worsen the glycemic control of diabetic patients. Close monitoring of blood glucose levels is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

If an appointment for a dose of Goserelin injection is missed, contact your doctor immediately and schedule the dose as soon as possible.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Amiodarone

Dolasetron

Ivabradine

Efavirenz

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Goserelin injection is usually administered by a qualified healthcare professional. Follow all the instructions given by your doctor. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Goserelin works by decreasing the amounts of certain hormones in the body. These hormones are required for the growth of certain cancer cells and uterine tissue.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Gonadotropin releasing hormone (GnRH) agonists, Hormonal antineoplastic agents

Schedule

Schedule H

Goserelin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 22 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00014

DailyMed - Zoladex- Goserelin acetate implant [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 22 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6bd94a89-f18a-45e5-d0a4-b343a4f0f03d&audience=consumer

Goserelin Implant: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601002.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 22 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

Goserelin (substance) [Internet]. Snomedbrowser.com. 2017 [cited 22 August 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/108771008

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Information on this page was last updated on 7 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.