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Gonal F 450 IU Injection

Manufactured byMerck Consumer Healthcare Ltd.
Description
Follicle stimulating hormone is a synthetic form of the naturally occuring hormone in the body. It is used along with other medicines to treat infertility in women and men.

Substitutes

List of substitutes for Gonal F 450 IU Injection

Gonal F Pen 450 IU Injection
Merck Consumer Healthcare Ltd.

Side effects

Major & minor side effects for Gonal F 450 IU Injection

  • Severe stomach ache
  • Bloating
  • Diarrhea
  • Severe nausea or vomiting
  • Pelvic pain
  • Rapid weight gain
  • Heavy vaginal bleeding
  • Unusual tiredness and weakness
  • Increased blood pressure
  • Depressed mood
  • Fever
  • Severe skin allergy

Uses of Gonal F 450 IU Injection

What is it prescribed for?

  • Female infertility
  • Assisted reproductive technique
  • Male infertility
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine is cumulative and can be observed when ovulation happens.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts until the end of the ovulation cycle.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    N/A
  • Can this medicine be taken during pregnancy?
    Use of this medicine is not recommended for women who are pregnant as the risk of birth defects and abnormalities in the newborn is very high. Consult your doctor regarding the risks associated with the use of this medicine during pregnancy.
  • Can this medicine be taken while breast-feeding?
    Use of this medicine by women who are breastfeeding is not recommended. If it becomes absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor regarding the risks associated with use while nursing an infant.

Allergy

This medicine is not recommended for use if you have a known history of allergy to it or any other Gonadotropin hormonal preparations.

Primary ovarian failure

This medicine is not recommended for use in women who are not able to produce eggs due to ovarian failure. This is indicated by high level of follicle stimulating hormone in the body.

Hormonal disorders

This medicine is not recommended for use in patients who have hormonal disorder due to abnormal secretions from thyroid, adrenal glands or the pituitary.

Tumor

This medicine is not recommended for use in patients who have a tumor of the reproductive organs due to caused due to high levels of sex hormones. It should not be used for patients who have a tumor of the pituitary gland or the hypothalamus.

Abnormal uterine bleeding

This medicine is not recommended for patients who have an abnormal uterine bleeding and the cause is undetermined.

Ovarian cysts

This medicine is not recommended for use in patients who have an ovarian cyst or enlargement which is of unknown origin and is not due to Polycystic ovary syndrome.

Primary testicular failure

This medicine is not recommended for treating infertility in men who are not able to produce sperm cells due to testicular failure.
Warnings for special population

Pregnancy

Use of this medicine is not recommended for women who are pregnant as the risk of birth defects and abnormalities in the newborn is very high. Consult your doctor regarding the risks associated with the use of this medicine during pregnancy.

Breast-feeding

Use of this medicine by women who are breastfeeding is not recommended. If it becomes absolutely necessary to use this medicine, then breastfeeding should be discontinued. Consult your doctor regarding the risks associated with use while nursing an infant.
General warnings

Hormone level determination

This medicine should be administered only after the requisite tests are completed to determine the safety of use.

Allergic skin reactions

Use of this medicine has been associated with severe allergic reactions in a few patients. Discontinue the use and report the instance of an allergic reaction to the doctor immediately.

Enlargement of ovaries

Use of this medicine has been associated with Ovarian hyperstimulation syndrome as well as uncomplicated ovarian enlargement. Dosing should be properly optimized to ensure that these unwanted effects do not occur.

Blood clots

Use of this medicine can cause blood clots and blockage of airways and other associated complications. Report the incidence of any disease related to heart, blood vessels, or lungs to the doctor.

Ectopic pregnancy

This medicine can cause fertilization of the egg outside the uterus in women being treated for infertility. This may increase the risk of miscarriage, stillbirth, premature labor etc. Consult your doctor about these risks before starting the medication.

Multiple pregnancy

This medicine can cause multiple pregnancy which is high risk and the risk of severe complications are very high for the mother and the baby. Consult your doctor about these risks before starting the medication.

Uterine cancer

Use of this medicine may increase the risk of developing uterine cancer. Consult your doctor about these risks before starting the medication. Report any instance of abnormal vaginal bleeding while taking this medicine to the doctor on priority.

Congenital abnormalities

Use of this medicine for assisted reproductive technique has been linked to genetic abnormalities of the newborn. You should ensure that the procedure is done under the supervision of a specialist having thorough experience in treating fertility disorders.

Missed Dose

Contact your doctor for further instructions if you have missed a scheduled dose of this medicine.

Overdose

Contact your doctor if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ganirelix

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Gonal F 450 IU Injection as instructed by the doctor. It is normally administered in the injection form given under the skin or muscle. It is advised to take this medicine under the supervision of your doctor or a trained healthcare professional.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
This medicine contains a highly purified form of follicle stimulating hormone and induces the growth and development of eggs produced in the ovaries. It also promotes the production of sperm in males.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Gonadotropins

Schedule

Schedule H

Bravelle, Fertinorm HP (urofollitropin) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 14 April 2017]. Available from:

http://reference.medscape.com/drug/bravelle-urofollitropin-342760#0

DailyMed - BRAVELLE- urofollitropin [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 14 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=46f7740f-c879-4a77-9a16-2821fd772641

Follicle stimulating hormone medical facts from Drugs.com [Internet]. Drugs.com. 2017 [cited 14 April 2017]. Available from:

https://www.drugs.com/mtm/follicle-stimulating-hormone.html

Urofollitropin | C42H65N11O12S2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 14 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/75409771#section=Top

Urofollitropin: Indication, Dosage, Side Effect, Precaution | CIMS India [Internet]. Mims.com. 2017 [cited 14 April 2017]. Available from:

http://www.mims.com/india/drug/info/urofollitropin/?type=full&mtype=generic#Actions
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Information on this page was last updated on 18 Apr 2017

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