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Glyxambi 25 mg/5 mg Tablets
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Glyxambi 25 mg/5 mg Tablets

Manufactured byBOEHRINGER INGELHEIM INDIA PVT LTD
ContainsEmpagliflozin (25 mg) + Linagliptin (5 mg)
Description
Glyxambi 25 mg/5 mg Tablets is a combination of Empagliflozin and Linagliptin. It is an anti-diabetic medicine used in the treatment of type 2 Diabetes mellitus. A condition in which your blood sugar levels are high because your body doesn't properly use insulin. This medicine helps in controlling blood sugar levels and prevents complications of diabetes such as blindness, kidney damage, stroke (reduced blood supply to your brain), and heart attack. Glyxambi 25 mg/5 mg Tablets shows side effects like rapid weight loss, feeling sick or being sick, stomach pain, excessive thirst, confusion, etc. This medicine can occasionally cause low blood sugar levels, the signs being sweating, dizziness, and shivering. To avoid these side effects, eat your meals on time and carry a sugar source (sweets or fruit juice) for immediate relief. Avoid using this medicine if you are allergic to it. Alcohol should be avoided while using this medicine as it can lower your blood sugar levels too. Glyxambi 25 mg/5 mg Tablets is recommended to be taken with food. Take Glyxambi 25 mg/5 mg Tablets as per the prescription. For the ease of remembering, take this tablet around the same time every day, preferably at the time you take breakfast. Do not stop taking this medicine unless advised by your doctor, even if your sugar levels are normal. Glyxambi 25 mg/5 mg Tablets should not be taken if you have Type I insulin-dependent Diabetes (a condition where your body is unable to produce insulin, hence you have to take insulin injections), diabetic ketoacidosis (high amounts of acid in your blood), or severe kidney or liver problems. Inform your doctor about any history of heart problems before taking this medication. If you are pregnant or are breastfeeding, inform your doctor before taking this medicine. Glyxambi 25 mg/5 mg Tablets is not recommended in children below 18 years of age.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Glyxambi 25 mg/5 mg Tablets

  • Bladder pain
  • Bloody or cloudy urine
  • Difficult or painful urination
  • Lower back pain
  • Fast heartbeat
  • Headache
  • Unusual tiredness or weakness
  • Nausea and vomiting
  • Inflammation of pancreas
  • Blurred vision
  • Sore throat
  • Cough
  • Itching and skin rash

Uses of Glyxambi 25 mg/5 mg Tablets

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Glyxambi 25 mg/5 mg Tablets to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The duration for which Glyxambi 25 mg/5 mg Tablets remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol during treatment with Glyxambi 25 mg/5 mg Tablets due to the increased risk of severe side effects.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Glyxambi 25 mg/5 mg Tablets.
  • Can this medicine be taken during pregnancy?
    Glyxambi 25 mg/5 mg Tablets is usually not advised during pregnancy because it might have significant side effects on your foetus. However, if you are pregnant your doctor may prescribe alternative medicine with the same medicinal effect.
  • Can this medicine be taken while breast-feeding?
    Avoid taking Glyxambi 25 mg/5 mg Tablets if you are breastfeeding. There is no sufficient information available to know whether this medicine can pass into your breast milk. Your doctor may prescribe a safer alternative with the same medicinal effect based on your clinical condition.

Allergy

Do not take Glyxambi 25 mg/5 mg Tablets if you are allergic to it. Inform your doctor if you experience any symptoms of allergic reactions such as skin rashes, itching/swelling (especially of your face/tongue/throat), severe dizziness or breathing difficulty etc.

Type 1 Diabetes mellitus

Type 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, is a condition in which the pancreas produces little or no insulin. Symptoms include increased thirst, frequent urination, hunger, fatigue, and blurred vision. Glyxambi 25 mg/5 mg Tablets is not recommended if you have type 1 diabetes mellitus.

Diabetic ketoacidosis

Diabetic ketoacidosis is a complication of diabetes that occurs when your body produces high levels of acids called ketones in the blood. It can be triggered by infection or other illnesses. Symptoms include thirst, frequent urination, nausea, abdominal pain, weakness, and confusion. Glyxambi 25 mg/5 mg Tablets is not recommended if you have a history of diabetic ketoacidosis due to the increased risk of worsening your condition.
Warnings for special population

Pregnancy

Glyxambi 25 mg/5 mg Tablets is usually not advised during pregnancy because it might have significant side effects on your foetus. However, if you are pregnant your doctor may prescribe alternative medicine with the same medicinal effect.

Breast-feeding

Avoid taking Glyxambi 25 mg/5 mg Tablets if you are breastfeeding. There is no sufficient information available to know whether this medicine can pass into your breast milk. Your doctor may prescribe a safer alternative with the same medicinal effect based on your clinical condition.
General warnings

Dehydration

Dehydration occurs when your body doesn't have enough water as it needs. Glyxambi 25 mg/5 mg Tablets may cause dehydration. Inform your doctor if you experience symptoms like dizziness, faintness, light-headedness, especially when you stand up.

Kidney dysfunction

Glyxambi 25 mg/5 mg Tablets should be taken with caution if you have any kidney troubles. This medicine is excreted through urine and taking this medicine while you have pre-existing kidney problems can worsen the condition of your kidney.

Urinary tract infections

Urinary tract infection is an infection in any part of the urinary system, the kidneys, bladder or urethra. Take Glyxambi 25 mg/5 mg Tablets with caution if you have serious urinary tract infections. Inform your doctor if you have symptoms of a urinary tract infection, such as a burning feeling when passing urine, a need to urinate often or right away, pain in the lower part of your stomach or pelvis, or blood in the urine, etc.

QT Prolongation

QT Prolongation is a condition of an irregular heartbeat. Glyxambi 25 mg/5 mg Tablets should be used with caution if you have a pre-existing heart problem due to the increased risk of worsening your condition.

Severe liver disease

If you have any pre-existing liver problem, Glyxambi 25 mg/5 mg Tablets should be used with caution as it may increase your risk of liver damage. Close monitoring of liver function tests is recommended.

Hypoglycemia

Hypoglycemia is a condition with decreased blood sugar levels. If you are prone to having low blood sugar level episodes, Glyxambi 25 mg/5 mg Tablets should be taken with caution. Inform your doctor about this condition. They will suggest tests to monitor your blood suagr level regularly.

Bullous pemphigoid

Bullous pemphigoid is a hypersensitivity reaction of the skin. Glyxambi 25 mg/5 mg Tablets should be used with caution and any unusual symptoms such as skin blisters or skin rashes should be reported to the doctor immediately.

Alcohol use

Excessive alcohol intake while on treatment with Glyxambi 25 mg/5 mg Tablets may cause a severe drop in blood sugar levels. Hence alcohol consumption should be avoided.

Use in children

Glyxambi 25 mg/5 mg Tablets is not recommended for use in children below 18 years of age since the safety and efficacy of its use are not clinically established.

Driving or Operating machines

Glyxambi 25 mg/5 mg Tablets may cause blurred vision or dizziness. It is advised that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose of Glyxambi 25 mg/5 mg Tablets as soon as you remember it. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose of Glyxambi 25 mg/5 mg Tablets.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol during treatment with Glyxambi 25 mg/5 mg Tablets due to the increased risk of severe side effects.
Interaction with Medicine

Aripiprazole

Clozapine

Dexamethasone

Beta blockers

Monoamine oxidase inhibitors (MAOIs)

Disease interactions

Hyperlipidemia

Hyperlipidemia means an increase in the level of fats (cholesterol) in your blood. Glyxambi 25 mg/5 mg Tablets should be used with caution if you have hyperlipidemia. This medicine can worsen your condition by increasing the level of bad cholesterol and reducing the level of good cholesterol in your blood. Suitable dose adjustment and safety monitoring may be required.

Hypotension

Hypotension is a decrease in blood pressure. Glyxambi 25 mg/5 mg Tablets should be used with caution if you have hypotension due to the increased risk of severe side effects. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine.

Pancreatitis

Pancreatitis is swelling of the pancreas (the organ that releases digestive enzymes). Glyxambi 25 mg/5 mg Tablets should be used with extreme caution if you ever had pancreatitis, gallstones (hard deposits of bile [digestive juice]) in the gallbladder (the organ in the upper right abdomen, below your liver) or a history of alcoholism. Inform your doctor if you experience any symptoms such as abdominal pain, nausea, vomiting, etc. Your doctor may advise you to discontinue this medicine in such cases.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Glyxambi 25 mg/5 mg Tablets as prescribed by your doctor. It can be taken with or without food. Do not take in larger or smaller amounts than prescribed. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. Consult your doctor if you experience any undesirable effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Glyxambi 25 mg/5 mg Tablets contains Empagliflozin and Linagliptin. Empagliflozin reduces sugar reabsorption from your kidneys and lowers blood sugar levels. Linagliptin works by increasing insulin release from the pancreas and also increases the activity of hormones that control blood sugar levels.
Legal Status

Unknown

Approved

Approved

Approved

Classification

Category

Antidiabetic combinations, SGLT-2 inhibitors, Dipeptidyl peptidase 4 inhibitors

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - GLYXAMBI- empagliflozin and linagliptin tablet, film coated. [online] Available at: < [Accessed 7 December 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ddbab689-f76c-488c-9613-4168d41dd730>

Ema.europa.eu. 2021. [online] Available at: < [Accessed 7 December 2021].

https://www.ema.europa.eu/en/documents/product-information/glyxambi-epar-product-information_en.pdf>

Glyxambi.com. 2021. Type 2 Diabetes Medication | Glyxambi (empagliflozin/linagliptin) tablets. [online] Available at: < [Accessed 7 December 2021].

https://www.glyxambi.com/>
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Information on this page was last updated on 11 Jan 2022

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