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Glifil M Tablet
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Glifil M Tablet

Manufactured byFOURRTS INDIA LABORATORIES PVT LTD
ContainsMetformin (250 mg) + Glibenclamide (2.5 mg)
Description
Glifil M Tablet is an anti-diabetic medicine containing Glibenclamide and Metformin. It is used for the treatment of type 2 diabetes in adults. Glifil M Tablet helps control blood sugar levels by increasing insulin (a hormone that enables your body to use sugar) release and preventing the breakdown of carbohydrates into sugar. Glifil M Tablet may cause side effects like headache, dizziness, nausea, diarrhoea, etc. Consult your doctor if these symptoms persist or if they become severe. Glifil M Tablet may also cause hypoglycaemia (low blood sugar levels) characterised by symptoms like sweating, dizziness, headache, and shaking. Thus, it is recommended to have regular meals and always carry a fast-acting sugar source such as fruit juice, candy, raisins, etc. Glifil M Tablet is a prescription medicine and should be taken exactly as advised by your doctor. Take it at the same time every day to maintain a constant level of this medicine in your body. Do not skip a dose or discontinue the treatment as it may cause an increase in your blood sugar levels. Glifil M Tablet is not recommended if you are allergic to it. Inform your doctor if you have kidney, liver, or heart problems before beginning the treatment. This medicine is not recommended for use in children and adolescents below 18 years of age. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before taking Glifil M Tablet.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Glifil M Tablet

  • Abdominal fullness
  • Yellowing of skin and eyes
  • Dark colored urine
  • Fever or chills
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Unusual bleeding
  • Fast heartbeat
  • Unusual tiredness and weakness
  • Nausea and vomiting
  • Diarrhoea
  • Abdominal pain
  • Low blood sugar levels
  • Chest discomfort
  • Headache
  • Runny Nose
  • Blurred vision

Uses of Glifil M Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time taken by Glifil M Tablet to show its effect is clinically unknown.
  • How long do the effects of this medicine last?
    The effect of Glifil M Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Glifil M Tablet as it may increase the risk of lactic acidosis (increased blood lactic acid levels). It may also affect the ability of this medicine to control your blood sugar levels.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with Glifil M Tablet.
  • Can this medicine be taken during pregnancy?
    Glifil M Tablet is not recommended for use in pregnancy due to a lack of safety data. Consult your doctor if you are pregnant before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Glifil M Tablet passes into breast milk. Hence is not recommended for use during breastfeeding. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Glifil M Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Diabetic ketoacidosis

Diabetic ketoacidosis is a serious complication of diabetes. It is a condition in which the blood becomes acidic due to chemicals called ketones when your body does not have enough insulin. If left untreated, it can lead to diabetic coma (a condition where you are unconscious and are not able to respond to your surroundings due to very low or high blood sugar levels). Glifil M Tablet is not recommended if you have this condition as it may worsen your health.

Type I Diabetes mellitus

Type 1 diabetes, also known as insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. Symptoms include increased thirst, frequent urination, hunger, fatigue, and blurred vision. Glifil M Tablet is not recommended if you have type 1 diabetes.

Severe kidney impairment

Glifil M Tablet is not recommended if you have severe kidney problems as it may cause complications such as lactic acidosis (acid build up in the blood).
Warnings for special population

Pregnancy

Glifil M Tablet is not recommended for use in pregnancy due to a lack of safety data. Consult your doctor if you are pregnant before taking this medicine.

Breast-feeding

It is not known whether Glifil M Tablet passes into breast milk. Hence is not recommended for use during breastfeeding. Consult your doctor if you are breastfeeding.
General warnings

Liver/Kidney diseases

Glifil M Tablet should be used with caution if you have any liver/kidney problems due to the increased risk of worsening your health condition. Your doctor may suggest a blood test for a better treatment plan.

Change of medications

Glifil M Tablet may increase your risk of sleepiness and impaired thinking when taken with medicines that have a sedative effect. Inform your doctor about all your current medicines including any herbs or supplements before beginning treatment with this medicine.

Use in Children

Glifil M Tablet is not recommended for use in children and adolescents below 18 years of age due to a lack of safety and efficacy data.

Lactic Acidosis

Glifil M Tablet may increase the risk of developing a condition called lactic acidosis (increased level of lactic acid in your blood). Hence, monitor your blood glucose levels, kidney and heart function during the treatment with this medicine.

Missed Dose

Try not to skip a dose of Glifil M Tablet. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take excess dose than prescribed by your doctor. Contact your doctor in case of an overdose with Glifil M Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Glifil M Tablet as it may increase the risk of lactic acidosis (increased blood lactic acid levels). It may also affect the ability of this medicine to control your blood sugar levels.
Interaction with Medicine

Clarithromycin

Estradiol

Gatifloxacin

Iodinated Contrast Media

Aloe Vera

ACE inhibitors

Disease interactions

Heart Disease

If you have heart or blood vessel conditions, take Glifil M Tablet with caution as it can increase the risk of heart failure, a condition in which the heart is unable to pump a sufficient amount of blood.

Hypoglycemia

Hypoglycemia is a condition characterized by a decrease in blood glucose levels. If you are prone to having low blood glucose level episodes, take Glifil M Tablet with caution. Monitor your blood glucose level regularly. Always carry a fast-acting sugar source (like sugar candy or fruit juice).

Hemolytic Anemia/G6PD Deficiency

Glucose--6-phosphate dehydrogenase (G6PD) deficiency is a genetic condition in which your red blood cells break down when exposed to certain medicines, infections, or stress. Glifil M Tablet is not recommended if you have this condition as it may result in haemolytic anaemia (low red blood cell count).

Vitamin B12 deficiency

If you are having vitamin B12 deficiency, take Glifil M Tablet with caution. This medicine interferes with the absorption of Vitamin B12 in your body. Talk to your doctor if you have such conditions.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Glifil M Tablet is used in the treatment of Type II Diabetes. Take this medicine with food or as prescribed by your doctor. Avoid taking more than the prescribed dose as it may increase the risk of side effects. Do not stop taking Glifil M Tablet without consulting your doctor. Your doctor may suggest regular monitoring of your blood sugar levels to check that your diabetes is under control. Regular follow-up visits with your doctor are recommended to evaluate your condition. Maintain a proper diet and do regular exercise to get the maximum benefits from the treatment. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Glifil M Tablet is a combination of Metformin and Glibenclamide. Glimepiride works by increasing the secretion of insulin (a hormone that enables your body to use sugar) from the pancreas and also improving the body's ability to use insulin efficiently. Metformin works by improving the body’s response to insulin and decreasing sugar production in the liver.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antidiabetic combinations

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Glyburide. [online] Available at: [Accessed 2 November 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3488

Pubchem.ncbi.nlm.nih.gov. 2021. Metformin. [online] Available at: [Accessed 2 November 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4091
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Information on this page was last updated on 15 Feb 2023

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.