Gliclazide

Description

Gliclazide is an oral anti-diabetic, it is used to lower the blood sugar level. It is used only in patients diagnosed with Type II Diabetes. It may be used along with Insulin or other medicines in order to achieve better control over the blood sugar levels. A controlled diet and exercise routine may give better results.

Side effects

Major & minor side effects for Gliclazide

  • Dizziness
  • Nausea or vomiting
  • Diarrhea
  • Confusion
  • Weakness
  • Sweating
  • Changes in vision
  • Decreased heartbeat
  • Abdominal pain
  • Constipation
  • Skin rash
  • Elevated liver enzymes

Uses of Gliclazide

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 4-6 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended when you are taking this medicine. Do not perform activities that require mental alertness like operating heavy machinery or driving a vehicle. Inform the doctor if you experience any undesired effect.
  • Is it habit forming?
    No habit forming tendencies were reported
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

Avoid taking this medicine if you have a known allergy to Gliclazide or any other medicine belonging to the class sulphonylureas.

Diabetic ketoacidosis

Avoid taking this medicine if you have repeated episodes of diabetic ketoacidosis.

Impaired kidney function

Avoid taking this medicine in patients with impaired kidney function or history of severe kidney injury.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Hypoglycemia

Gliclazide is not recommended in the patients with hypoglycemia as it increases the risk of lowering of blood glucose levels. Inform the doctor if you experience any symptoms like dizziness, confusion or weakness.

Impaired kidney function

Gliclazide is not recommended in the patients suffering from a severe kidney imparement.

Impaired liver function

Gliclazide is not recommended in the patients suffering from a severe liver impairment.

Hemolytic Anemia

Gliclazide is not recommended in the patients with glucose-6-phosphate (G6PD) deficiency due to the risk of developing hemolytic anemia.

Missed Dose

The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.

Overdose

It is recommended to discontinue the medicine and contact your doctor immediately if an overdose is suspected. Symptoms like dizziness, confusion, increased heartbeat, tremor and sweating after taking the medicine should be reported immediately.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Consumption of alcohol with Gliclazide may increase the hypoglycaemic effects which may lead to the onset of hypoglycaemic coma.

Instructions

Consumption of alcohol is not recommended when you are taking this medicine. Do not perform activities that require mental alertness like operating heavy machinery or driving a vehicle. Inform the doctor if you experience any undesired effect.
Interaction with Medicine

Miconazole

Phenylbutazone

Chlorpromazine

Glucocorticoids

Disease interactions

Hemolytic Anemia/G6PD Deficiency

Gliclazide is not recommended for use in people suffering from Hemolytic Anemia. Reporting this condition to the doctor is a must. In such cases, alternate medication not belonging to Sulfonylureas should be considered.

Heart Disease

Gliclazide should be administered with extreme caution if you suffer from any disease of heart and blood vessels.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Gliclazide as directed by your doctor. Follow the instructions mentioned on the label. The medicine should be taken orally with breakfast or the first meal of the day. An adequate amount of water should be consumed while taking this medicine.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by reducing the blood glucose levels by increasing the secretion of insulin.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Sulfonylureas

Schedule

Schedule H

[Internet]. 2017 [cited 21 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/31089

Gliclazide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 March 2017]. Available from:

https://www.drugbank.ca/drugs/DB01120

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 16 November 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database

[Internet]. Davisplus.fadavis.com. 2017 [cited 16 November 2017]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/gliclazide.pdf

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Information on this page was last updated on 8 Feb 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.