Gemigliptin

Description

Gemigliptin is an antidiabetic medicine used alone or in a combination with other medicines to treat type 2 diabetes in adult patients. Patients are advised to follow a strict diet and exercise regimen along with this medicine for the best possible effect. This medicine is not recommended for use in patients suffering from type 1 diabetes and diabetic ketoacidosis.

Side effects

Major & minor side effects for Gemigliptin

  • Diarrhea
  • Indigestion
  • Stomach discomfort
  • Itching of skin
  • Skin rash
  • Constipation
  • Nausea
  • Dry mouth
  • Joint pain

Uses of Gemigliptin

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with known allergy to gemigliptin, any other dipeptidyl peptidase-4 inhibitors, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Kidney disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Arthralgia

This medicine may cause severe joint pain and hence should be used with caution in patients with severe arthralgia (joint pain) due to the increased risk of worsening the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Pancreatitis

This medicine should be used with extreme caution in patients with a known history of pancreatitis due to the increased risk of recurrent pancreatitis. Report any symptoms such as abdominal pain, nausea, vomiting, etc. to the doctor immediately. Treatment with this medicine should be discontinued immediately if symptoms worsen. An alternative treatment option may be necessary in such cases based on the clinical condition.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember it. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Dexamethasone

Acetazolamide

Gatifloxacin

Benazepril

Clozapine

Disease interactions

Pancreatitis

This medicine should be used with extreme caution in patients with a known history of pancreatitis due to the increased risk of recurrent pancreatitis. Report any symptoms such as abdominal pain, nausea, vomiting, etc. to the doctor immediately. Treatment with this medicine should be discontinued immediately if symptoms worsen. An alternative treatment option may be necessary in such cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with mild to moderate kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cardiovascular disorders

This medicine should be used with caution in patients with cardiac disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustment or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. It can be taken with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not change the dose or duration of use without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Gemigliptin increases insulin and lowers glucagon production. This results in lowering of the blood glucose levels.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Dipeptidyl peptidase 4 inhibitors

Schedule

Schedule H

Gemigliptin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 6 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB12412

Gemigliptin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 6 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Gemigliptin

[Internet]. Products.sanofi.in. 2018 [cited 6 September 2018]. Available from:

http://products.sanofi.in/Zemiglo.pdf

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Information on this page was last updated on 8 Mar 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.