Ganirelix

Description

Ganirelix is used along with other hormonal medicines in women who are under fertility treatment (controlled ovarian stimulation) to suppress the premature luteinizing hormone (LH) surges and prevents the release of a premature egg from the ovary.

Side effects

Major & minor side effects for Ganirelix

  • Abdominal or stomach pain
  • Diarrhea
  • Rapid weight gain
  • Bloating
  • Headache
  • Redness, pain or swelling at the injection site
  • Dizziness
  • Fast heartbeat
  • Skin rash, hives, or itching
  • Tightness in chest
  • Unusual tiredness or weakness
  • Cough
  • Difficulty in swallowing
  • Shortness of breath

Uses of Ganirelix

What is it prescribed for?

  • Prevention of luteinizing hormone (LH) surges in women during controlled ovarian hyperstimulation
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to ganirelix, GnRH, any other GnRH analog, or any other inactive ingredients present along with it.

Pregnancy

This medicine is not recommended for use in pregnant women.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Use in children

This medicine is not recommended for use in children.

Allergy

This medicine should be used with extreme caution in women with signs and symptoms of severe allergic conditions such as hay fever, skin rash, itchy skin, facial swelling, shortness of breath, wheezing, etc. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss an appointment for a dose of Ganirelix injection, contact your doctor immediately and schedule the dose as soon as possible.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Follicle Stimulating Hormone

Human Chorionic Gonadotropin

Gonadorelin

Menotropins

Triptorelin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Consult the doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine acts by blocking the release of luteinizing hormone (LH) responsible for the release of an egg from the ovary. This helps in preventing the premature release of the egg.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Gonadotropin releasing hormone (GnRH) antagonist

Schedule

Schedule H

[Internet]. Drugbank.ca. 2018 [cited 14 December 2018]. Available from:

https://www.drugbank.ca/salts/DBSALT001230

[Internet]. Accessdata.fda.gov. 2018 [cited 14 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021057s010lbl.pdf

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 14 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Ganirelix

DailyMed - Ganirelix Acetate- ganirelix acetate injection, solution [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 23 August 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=96118395-557e-4998-842d-424a59d574b6

Fyremadel 0.25 mg/ 0.5 ml solution for injection in pre-filled syringe - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 23 August 2019]. Available from:

https://www.medicines.org.uk/emc/product/2681

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Information on this page was last updated on 23 Aug 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.