Ganciclovir

Description

Ganciclovir is an antiviral medicine used for the prevention of Cytomegalovirus (CMV) infection which may occur after an organ transplantation. It is also used to treat CMV eye infection in patients with acquired immunodeficiency syndrome (AIDS). This medicine should be used with caution in patients with a known history of seizure disorders due to the increased risk of recurrent seizures.

Side effects

Major & minor side effects for Ganciclovir

  • Chills
  • Headache
  • Shortness of breath
  • Diarrhea
  • Abdominal and stomach pain
  • Nausea and Vomiting
  • Back pain
  • Seizures
  • Swelling of legs
  • Itching
  • Decreased urine output

Uses of Ganciclovir

What is it prescribed for?

  • Cytomegalovirus Retinitis (CMV)
  • Cytomegalovirus Prophylaxis
  • Acute herpetic keratitis
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its effect is not clinically established.
  • Duration of effect
    The time until which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ganciclovir or any other medicine of the same class.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.
General warnings

Hematologic Toxicity

This medicine should be used with caution in patients with a known history of blood disorders due to the increased risk of worsening of the patient's condition. Close monitoring of blood cell counts is necessary while receiving treatment with this medicine. Replacement with a suitable alternative may be required based on the clinical condition of the patient.

Renal dysfunction

Ganciclovir should be used with extreme caution in patients with renal diseases due to the increased risk of severe side effects. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.

Impairment of Fertility

This medicine should be used with caution due to the increased risk of impairment of fertility in both men and women. Replacement with a suitable alternative may be required based on the clinical condition of the patient. Do not stop the use of any medicine without consulting your doctor.

Missed Dose

If an oral dose of Ganciclovir is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one. Since the intravenous form of this medicine is usually administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of missing a dose is very low. Gel: If the dose Ganciclovir gel is missed, instill it as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Infliximab

Zidovudine

Didanosine

Disease interactions

Bone marrow suppression

This medicine should be used with extreme caution in patients with a known history of blood disorders and bone marrow suppression due to the increased risk of worsening of the patient's condition. You may require a dose adjustment and more frequent complete blood count monitoring to safely use this medicine. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Renal Dysfunction

Ganciclovir should be used with extreme caution in patients with kidney diseases due to the increased risk of severe adverse effects. Kidney function should be assessed before initiating the treatment. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Use Ganciclovir exactly as instructed by the doctor. Do not use larger or smaller amounts than prescribed. Ensure that the course of treatment is completed. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Ganciclovir works by blocking the growth and reproduction of cytomegalovirus. This helps in preventing the spread of the disease.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Purine nucleosides

Schedule

Schedule H

[Internet]. 2017 [cited 28 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24747

DailyMed: Ganciclovir capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 28 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3406db8a-5ae9-4120-94bd-036701adbeca

Ganciclovir - DrugBank [Internet]. Drugbank.ca. 2017 [cited 28 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB01004

Ganciclovir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 28 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a605011.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 28 August 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 14 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.