Galvus Met 50/500 mg Tablet

Manufactured byNOVARTIS INDIA LTD
ContainsMetformin (500 mg) + Vildagliptin (50 mg)
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Description

Galvus Met 50/500 mg Tablet is a combination medicine used for the treatment of type 2 diabetes mellitus. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect. This medicine is not recommended for use in patients below 18 years of age.

Substitutes

List of substitutes for Galvus Met 50/500 mg Tablet

Side effects

Major & minor side effects for Galvus Met 50/500 mg Tablet

  • Headache
  • Dizziness
  • Weakness
  • Constipation
  • Weight gain
  • Sore throat
  • Excessive sweating
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Nausea and vomiting
  • Diarrhea
  • Abdominal pain
  • Hypoglycemia
  • Lactic Acidosis
  • Chest discomfort
  • Runny Nose
  • Belching and Heartburn
  • Swollen joints

Uses of Galvus Met 50/500 mg Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1-3 hours of administration.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to vildagliptin, any other dipeptidyl peptidase 4 inhibitors, metformin, any other biguanides, or any other inactive ingredients present along with these medicines.

Type I Diabetes mellitus

This medicine is not recommended for use in patients with type 1 diabetes mellitus since it is not effective in treating this condition.

Diabetic ketoacidosis

This medicine is not recommended for use in patients with a known history of diabetic ketoacidosis due to the increased risk of worsening of the patient's condition.

Hepatic impairment

This medicine is not recommended for use in patients with a known history of hepatic impairment due to the increased risk of serious adverse effects.

Renal impairment

This medicine is not recommended for use in patients with an impairment of kidney function, serum creatinine >= 1.5 mg/dl for males and >= 1.4 mg/dl for females.

Metabolic Acidosis

This medicine is not recommended for use in patients with metabolic acidosis since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the medicine or to discontinue breastfeeding based on your clinical condition.
General warnings

Insulin secretagogues

This medicine should be used with caution in patients who are using insulin secretagogues due to the increased risk of hypoglycemia. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustment or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Bullous pemphigoid

This medicine should be used with caution due to the increased risk of bullous pemphigoid, a hypersensitivity reaction of the skin. Any unusual symptoms such as skin blisters or skin rashes should be reported to the doctor on priority. Therapy with the medicine may be discontinued based on the clinical condition of the patient.

Arthralgia

This medicine should be used with caution in patients with a known history of severe arthralgia due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Pediatric Use

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Kidney disease

This medicine should be used with caution in patients with a known history of kidney disease due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Stress

Use of this medicine should be discontinued in patients exposed to stressful conditions such as a fever, trauma, surgeries, or accidents since it may not be effective in controlling blood sugar levels in these conditions. Replacement with a suitable alternative should be considered under your doctor's supervision.

Diarrhea

This medicine may cause diarrhea when therapy is initiated. In most cases, diarrhea subsides by itself. Contact your doctor if the problem persists for longer durations. Therapy may need to be discontinued in some cases based on the clinical condition.

Dizziness

This medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating heavy machinery if you experience dizziness during treatment with this medicine.

Lactic Acidosis

This medicine may cause lactic acidosis, which may be fatal, in some patients. This risk is especially higher in patients suffering from heart diseases, kidney diseases, etc. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Interaction with Medicine

Amlodipine

Aripiprazole

Clozapine

Estradiol

Gatifloxacin

Iodinated Contrast Media

Aloe Vera

Dexamethasone

Dopamine

Acetazolamide

Bexarotene

Disease interactions

Pancreatitis

This medicine should be used with extreme caution in patients with a known history of pancreatitis due to the increased risk of recurrent pancreatitis. Report any symptoms such as abdominal pain, nausea, vomiting, etc. to the doctor immediately. Therapy with the medicine may be discontinued based on the clinical condition of the patient.

Cardiac failure

This medicine should be used with caution in patients with cardiac failure due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Vitamin B12 deficiency

This medicine should be used with extreme caution in patients with vitamin B12 deficiency since it may worsen the patient's condition. Appropriate vitamin B12 supplementation and dose adjustments may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as prescribed by the doctor. It is advised to take this medicine with meals. Your dose is likely to change over time based on the therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. Do not change the dose or duration of use without consulting your doctor. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels. Consult the doctor if you experience any undesirable side effects.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Metformin decreases absorption of glucose from the intestines and increases the action of insulin in the body. Vildagliptin increases insulin and lowers glucagon production. The combination is thus better effective than monotherapy in lowering the blood glucose levels.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antidiabetic combinations, Oral Biguanides, Dipeptidyl peptidase 4 inhibitors

Schedule

Schedule H

DailyMed - Metformin hcl tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d98aea3-35ba-447a-b88f-a5a20b612b2f

[Internet]. 2017 [cited 19 October 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/20734

Vildagliptin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB04876

[Internet]. Unilab.com.ph. 2017 [cited 28 December 2017]. Available from:

https://www.unilab.com.ph/assets/product-info/proglin-met.pdf
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