Gadopentetate dimeglumine

Description

Gadopentetate dimeglumine is used as a magnetic resonance imaging (MRI) contrast agent to enhance the quality of visualizing the blood vessels, organs, and other non-bony tissues to detect or diagnose certain disorders of the brain, blood vessels, and spine.

Side effects

Major & minor side effects for Gadopentetate dimeglumine

  • Blurred vision
  • Dizziness
  • Discoloration of the skin
  • Numbness
  • Rash
  • Headache
  • Pain at the injection site

Uses of Gadopentetate dimeglumine

What is it prescribed for?

  • Central nervous system magnetic resonance imaging
  • Vascular magnetic resonance imaging
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this contrast agent to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this contrast agent remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    Gadopentetate dimeglumine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving Gadopentetate dimeglumine.
  • Usage while breast-feeding?
    Gadopentetate dimeglumine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving Gadopentetate dimeglumine.

Allergy

Gadopentetate dimeglumine is not recommended for use if you have a known allergy to it or any other components present along with it.
Warnings for special population

Pregnancy

Gadopentetate dimeglumine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving Gadopentetate dimeglumine.

Breast-feeding

Gadopentetate dimeglumine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving Gadopentetate dimeglumine.
General warnings

Hypotension

Gadopentetate dimeglumine may lower the blood pressure in some patients on therapy. Close monitoring of the blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Allergic reactions

This contrast agent should be used with extreme caution in patients with a history of an allergic reaction to contrast media, bronchial asthma or allergic disorders. If symptoms of allergic reactions occur, discontinue immediately and initiate appropriate treatment.

Other medicines

Gadopentetate dimeglumine may interact with many medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before receiving Gadopentetate dimeglumine.

Missed Dose

Since Gadopentetate dimeglumine is given during procedures, therefore the likelihood of missing a dose is very less.

Overdose

Since Gadopentetate dimeglumine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Verapamil

Felodipine

Amlodipine

Diltiazem

Disease interactions

Kidney impairment

Gadopentetate dimeglumine is not recommended for use in patients with chronic, severe kidney disease, or acute kidney injury due to the increased risk of adverse effects. It should only be used in patients if diagnostic information is required and not available with non- contrasted MRI or other modalities.
Food interactions
Information not available.
Lab interactions
Information not available.
Gadopentetate dimeglumine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to Gadopentetate dimeglumine. Report all your current medicines as well as your medical conditions to the doctor before receiving Gadopentetate dimeglumine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This contrast agent allows more clear visualization of blood vessels, organs, and associated tissues during a magnetic resonance imaging (MRI).
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Magnetic resonance imaging contrast media

Schedule

Schedule H

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 7 January 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Magnevist

[Internet]. Accessdata.fda.gov. 2019 [cited 7 January 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019596s057lbl.pdf

[Internet]. Drugbank.ca. 2019 [cited 7 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB00789

DailyMed - Gadopentetate Dimeglumine- gadopentetate dimeglumine injection [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 11 September 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=25c782d4-7b45-4437-b80c-54271e3831b9

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Information on this page was last updated on 13 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.