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Gabaprime NT Tablet
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Gabaprime NT Tablet

Manufactured bySTARUS PHARMACEUTICALS PVT LTD
ContainsGabapentin (400 mg) + Nortriptyline (10 mg)
Description
Gabaprime NT Tablet is a combination of Gabapentin and Nortriptyline. It is used for the treatment of neuropathic pain (nerve pain that occurs because of damage or injury to your nerves). Nerve damage can occur due to various conditions like diabetes, cancer, spine disorders, thyroid problems, or HIV (Human immunodeficiency virus) infection. Gabaprime NT Tablet works by blocking the movement of pain signals in your brain. Gabaprime NT Tablet shows some common side effects like constipation, weight gain, dry mouth, difficulty in urination, dizziness and drowsiness. This medicine is known to cause sleepiness and/or drowsiness, so avoid doing activities that require mental focus like driving or operating heavy machinery. Keep a check on your mood and behaviour as this medicine can cause mood and behaviour changes like suicidal tendencies. Gabaprime NT Tablet can be taken with or without food, preferably at dinner time. Try taking this medicine around the same time every day to maintain a constant level in your body. Take this medicine for the prescribed duration even if you feel better after few doses. Complete the whole course to see the maximum benefits. If you forget to take a dose of Gabaprime NT Tablet, take it as soon as you remember it. However, do not double up the next dose to compensate for the missed dose. Gabaprime NT Tablet is not recommended in children and patients with a history of a heart attack. Inform your doctor if you have liver, kidney or other diseases as they might change the therapeutic effects of this medicine. Your doctor may adjust your dose to use this medicine safely. Gabaprime NT Tablet is not used in pregnancy and in breastfeeding women unless prescribed by your doctor. Your doctor will prescribe this medicine only when the benefits outweigh the risks, or else another suitable medicine may be prescribed.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Gabaprime NT Tablet

  • Dizziness
  • Uncontrolled eye movements
  • Constipation
  • Dry mouth
  • Lower back pain
  • Drowsiness
  • Weight gain
  • Blurred vision
  • Weakness in arms, hands, legs or feet
  • Breast enlargement
  • Skin rash
  • Difficult or painful urination
  • Mood changes

Uses of Gabaprime NT Tablet

What is it prescribed for?

  • Postherpetic Neuralgia
  • Neuropathic pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    It is not known when Gabaprime NT Tablet will start its action after intake. However, you may have to continue this medicine for a few weeks to see maximum benefits.
  • How long do the effects of this medicine last?
    It is not known how long Gabaprime NT Tablet remains active in your body.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Gabaprime NT Tablet as it may increase the risk of side effects like dizziness, drowsiness, and difficulty in concentration.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Gabaprime NT Tablet.
  • Can this medicine be taken during pregnancy?
    Gabaprime NT Tablet is not recommended for use in pregnancy as it may harm your developing foetus. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks. If you are pregnant, consult your doctor.
  • Can this medicine be taken while breast-feeding?
    Gabaprime NT Tablet is present in breastmilk. Therefore, this medicine is not recommended while breastfeeding unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine. If this medicine is used, your doctor may advise you to closely monitor your baby for any undesired side effects.

Allergy

Avoid taking Gabaprime NT Tablet if you are previously allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Heart attack

Gabaprime NT Tablet is not recommended if you are recovering from a recent heart attack. This medicine affects the functioning of your heart which could result in excessively low blood pressure and other heart problems. Thus, it may worsen your condition.
Warnings for special population

Pregnancy

Gabaprime NT Tablet is not recommended for use in pregnancy as it may harm your developing foetus. This medicine is prescribed by your doctor only when the potential benefits outweigh the risks. If you are pregnant, consult your doctor.

Breast-feeding

Gabaprime NT Tablet is present in breastmilk. Therefore, this medicine is not recommended while breastfeeding unless absolutely necessary. All the risks and benefits should be discussed with your doctor before using this medicine. If this medicine is used, your doctor may advise you to closely monitor your baby for any undesired side effects.
General warnings

Allergic reactions

Gabaprime NT Tablet may cause allergic reactions in some people. Seek immediate medical attention if you notice any symptoms such as skin rash, severe itching/swelling anywhere on the body, etc.

Driving or operating machines

Gabaprime NT Tablet may cause dizziness, confusion, or disorientation in some people. Hence, avoid performing activities such as driving or operating machines if you experience any of these symptoms.

Suicidal tendencies

Gabaprime NT Tablet may cause changes in mood and behaviour and may lead to suicidal tendencies. Report any mood changes to your doctor immediately so that counselling can be done.

Withdrawal symptoms

Continue taking Gabaprime NT Tablet for the prescribed duration even if your pain is relieved. If you discontinue this medicine suddenly, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, excessive sweating, nausea, and vomiting. A gradual dose reduction is recommended before stopping the medicine.

Surgery

Use of Gabaprime NT Tablet is not recommended if you are planning to undergo surgery as it can affect the functioning of your heart which is not ideal in surgeries. Inform your doctor as this medicine should be discontinued several days before your surgery.

Weight gain

Gabaprime NT Tablet may cause weight gain in some individuals. This medicine can make you feel more hungry, thereby increasing the chances of putting on more weight. Avoid soft drinks, oily food, chips, cakes, biscuits, sweets, etc. Eat a healthy balanced diet such as fruits, vegetables, and low-calorie foods.

Liver disease

Gabaprime NT Tablet is broken down and absorbed by the liver. If you have liver problems, you need special dose consideration while taking this medicine due to the increased risk of liver damage. Dose adjustment will be done by your doctor based on your clinical condition.

Use in children

Gabaprime NT Tablet is not recommended for use in children below 18 years of age as not many studies are done to understand its safety and efficacy in children.

Sexual problems

Gabaprime NT Tablet may cause decreased sexual desire, erectile dysfunction (a condition where a man is unable to achieve and/or maintain an erection adequate enough for sexual intercourse), and inability to reach orgasm. Report any such sexual problems to your doctor. Avoid discontinuation of the medicine without consulting your doctor.

Missed Dose

If you forget to take a dose of Gabaprime NT Tablet, take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek immediate medical attention or consult your doctor in case of an overdose with Gabaprime NT Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Gabaprime NT Tablet as it may increase the risk of side effects like dizziness, drowsiness, and difficulty in concentration.
Interaction with Medicine

Duloxetine

Glimepiride

Ondansetron

Buprenorphine

Metoprolol

Disease interactions

Kidney Disease

Gabaprime NT Tablet is filtered by the kidney and moved out of the body through urine. Individuals with kidney problems need special dose consideration while taking this medicine due to the increased risk of kidney damage. Dose adjustment may be necessary based on your clinical condition.

Heart Disease

Gabaprime NT Tablet should be used with extreme caution if you have heart problems due to the risk of altered blood pressure levels, irregular heart rate, syncope (loss of consciousness), stroke and other heart abnormalities. Your heart functions, including ECG changes, need to be closely monitored while taking this medicine.

Pheochromocytoma

If you have pheochromocytoma (a tumour in your adrenal glands, above the kidneys), use Gabaprime NT Tablet with caution as it can cause a severe increase in your blood pressure that can lead to a stroke. Your doctor may adjust the dose or prescribe another alternative medicine if required.

Diabetes Mellitus

Use Gabaprime NT Tablet with caution if you have Diabetes. Long-term therapy with this medicine may alter your blood sugar levels. Monitor your blood sugar levels regularly while taking this medicine. Dose adjustments or the use of alternative medicine may be necessary based on your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Gabaprime NT Tablet with or without food as instructed by your doctor. Inform your doctor if you have any other health issues or are under any medications before starting the medicine. You should not stop taking this medicine unless prescribed by your doctor as you can experience withdrawal symptoms. You may gain some weight while taking this medicine so it is important to exercise daily and eat a healthy diet to maintain your weight. Antacid reduces the amount of Gabaprime NT Tablet absorbed by your body. Hence, take an antacid two hours before or after taking this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Gabaprime NT Tablet is composed of Gabapentin and Nortriptyline. Gabapentin alters the calcium channel activity of the nerve cells and interferes with the pain signals travelling through the damaged nerves and the brain. Thus, it relieves pain due to nerve damage. Nortriptyline is an antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) to stop the movement of pain signals in the brain.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Tricyclic antidepressants

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - NORTRIPTYLINE HYDROCHLORIDE capsule. [online] Available at: < [Accessed 7 April 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b58d473a-b19f-4d2a-b1ae-dd398d7a29e1>

Pubchem.ncbi.nlm.nih.gov. 2021. Nortriptyline. [online] Available at: < [Accessed 12 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Nortriptyline>

Pubchem.ncbi.nlm.nih.gov. 2021. Gabapentin. [online] Available at: < [Accessed 12 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Gabapentin>

Medicines.org.uk. 2021. Gabapentin Mylan 600 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 4 August 2021].

https://www.medicines.org.uk/emc/product/8541/smpc>
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Information on this page was last updated on 20 Oct 2021

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