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Fourderm AF Cream
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Fourderm AF Cream

Manufactured byCipla Ltd.
ContainsBetamethasone (0.61 mg) + Gentamicin (1 mg) + Clotrimazole (10 mg) + Benzyl Alcohol (10 mg)
Description
Fourderm AF Cream is a combination medicine which may be used for the treatment of steroid responsive fungal and bacterial infections of the skin including eczema and psoriasis. This medicine is not recommended for use in patients less than 12 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Fourderm AF Cream

  • Skin rash
  • Redness of skin
  • Drying and cracking of skin
  • Acne
  • Change in skin color
  • Dry skin
  • Burning or stinging sensation at application site

Uses of Fourderm AF Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to betamethasone, gentamicin, clotrimazole, benzyl alcohol, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Opthalmic use

This medicine is not recommended for use in the eyes. Both purposeful and accidental application of this medicine into the eyes should be avoided.

Use only in confirmed infection

This medicine should not be used until the infection is diagnosed by a doctor. Other diseases may also show similar symptoms.

Other medicines

Fourderm AF Cream may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Allergic reactions

This medicine has the potential of causing moderate to a severe allergic reaction in the body. Any instance indicative of allergic reactions should be reported to the doctor in the first instance. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Resistance

This medicine should be used for the complete prescribed course even when the symptoms get better. The infection may recur and the fungi may get less sensitive to the medicine, resulting in drug resistance, if it is not used for the complete prescribed course.

Use in Children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.

External Use Only

This medicine is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

BCG vaccine

BCG vaccine

Neomycin

Neomycin

Streptomycin

Streptomycin

Rocuronium

Rocuronium

Pancuronium

Pancuronium

Disease interactions

Hyperadrenocorticism

This medicine should be used with caution in patients having a high level of adrenal hormones in the body due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Ocular Toxicities

This medicine should be used with extreme caution in patients with a history of cataracts, glaucoma, or increased intraocular pressure due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Infections

This medicine should be used with extreme caution in patients with latent or active infections since this medicine can suppress the immune system and worsen the patient's condition. This risk is especially higher in patients on high doses of this medicine for a prolonged period of time. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diaper rash

This medicine should not be applied to diaper rashes since the risks of systemic absorption and associated complications are significantly high. Replacement with a suitable alternative should be considered under your doctor's supervision.

Diabetes

Use of this medicine may alter blood glucose levels in patients with diabetes. This interaction is based on the amount applied and the size of the application area. Close monitoring of blood glucose levels is necessary for such patients during treatment with this medicine. Replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of the cream/ointment to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor. Contact your doctor if symptoms do not improve or resolve after two weeks of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Betamethasone works by decreasing the release of certain substances that cause swelling of the internal organs as well as external swelling and irritation. It also works by suppressing or partially preventing the effect of the immune system. Clotrimazole works by inhibiting the growth of individual Candida or fungi by altering the permeability of their cell wall. Gentamicin works by inhibiting the protein synthesis which is essential for the bacteria to grow. Benzyl alcohol is a preservative.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Glucocorticoids, Aminoglycosides, Topical antifungals

Schedule

Schedule H

Betamethasone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00443

DailyMed - Betamethasone dipropionate cream BETAMETHASONE DIPROPIONATE- betamethasone dipropionate ointment BETAMETHASONE DIPROPIONATE- betamethasone dipropionate lotion [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=97dde5f5-a865-4af2-b562-8da72c8475f3

DailyMed - GENTAMICIN SULFATE- gentamicin sulfate ointment [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 19 March 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f986fa2a-e667-452f-be4c-bad8588af525

DailyMed - Clotrimazole- clotrimazole cream [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c0f58a0d-a304-41f9-bbdf-c2e488230cf0
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Information on this page was last updated on 19 Mar 2019

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