Fosfestrol

Description

Fosfestrol is an inactive synthetic nonsteroidal form of estrogen which is converted to active estrogen in the body upon administration. This medicine is used in the treatment of prostate cancer.

Side effects

Major & minor side effects for Fosfestrol

  • Abdominal cramps
  • Impotence
  • Skin rash
  • Enlargement of breasts in males
  • Fluid Retention
  • Nausea and vomiting
  • Dizziness
  • Loss of appetite

Uses of Fosfestrol

What is it prescribed for?

  • Prostate Cancer
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients who have a known allergy to Fosfestrol or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Cardiovascular risks

This medicine should be used with caution in patients having heart disease or are exposed to the risk factors due to the increased risk of adverse effects. Appropriate dose adjustments and more frequent clinical monitoring are recommended while using this medicine. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Diabetes mellitus

This medicine should be used with caution in patients with diabetes due to the increased risk of adverse effects. Appropriate dose adjustments and more frequent clinical monitoring are recommended while using this medicine. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Blood vessel disorder

This medicine should be used with caution in patients having a disease of blood vessels around the brain or have any risk of blood clots in the blood vessels due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments and more frequent clinical monitoring are recommended while using this medicine. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Use in elderly

This medicine should be used with caution in elderly patients since the risk of adverse effects is significantly high.

Liver disease

This medicine should be used with caution in patients with liver impairment due to the increased risk of adverse effects. Appropriate dose adjustments and more frequent clinical monitoring of liver function tests are recommended while using this medicine. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during treatment with this medicine.

Missed Dose

Injection: Since this medicine is usually administered in a hospital by a qualified healthcare professional, the likelihood of a missed dose is very low. However, if you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately for further instructions. Tablet: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Tablet: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine. Oral: Take this medicine exactly as instructed by your doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
This medicine works by inhibiting the action of male hormones on the prostate.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Estrogens, Antineoplastics

Schedule

Schedule H

[Internet]. Nature.com. 2018 [cited 28 September 2018]. Available from:

https://www.nature.com/articles/4500235.pdf?origin=ppub

[Internet]. Netdoctor. 2018 [cited 28 September 2018]. Available from:

https://www.netdoctor.co.uk/medicines/cancer-drugs/a6852/honvan-tablets-discontinued-in-the-uk/

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Information on this page was last updated on 8 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.