Fortwin Injection 1 ml

Manufactured byRanbaxy Laboratories Ltd.
ContainsPentazocine
Description

Fortwin Injection 1 ml is a potent analgesic medicine used in the treatment of moderate to severe pain for which alternative treatments are inadequate. This medicine is also used as a pre-anesthetic or preoperative medication and as a supplement to surgical anesthesia. This medicine should be used with extreme caution due to the increased risk of addiction.

Side effects

Major & minor side effects for Fortwin Injection 1 ml

  • Hypersensitivity
  • Drowsiness
  • Change in mood
  • Headache
  • Constipation
  • Nausea and vomiting
  • Allergic skin reaction
  • Respiratory depression
  • Trouble sleeping
  • Blurred vision

Uses of Fortwin Injection 1 ml

What is it prescribed for?

  • Anesthesia
  • Moderate to severe pain
  • Labor pain
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 15 to 30 minutes of an oral, subcutaneous, or intramuscular dose and within 2 to 3 minutes of an intravenous dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 3 hours.
  • Safe with alcohol?
    Alcohol should not be consumed while receiving this medicine since it may increase the risk of drowsiness, lightheadedness, impairment in thinking and judgment, etc. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    Habit forming tendency has been reported, especially after prolonged use. Patients should be monitored closely for any signs of abuse or addiction. Proper assessment of the patient, periodic reevaluation, and proper dispensing is recommended to limit the abuse of this medicine.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor will prescribe a safer alternative based on your clinical condition.

Hypersensitivity

This medicine is not recommended for use in patients with a known allergy to pentazocine or any other components present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor will prescribe a safer alternative based on your clinical condition.
General warnings

Use in pediatrics

This medicine is not recommended for use in children less than 1 year of age.

Respiratory depression

This medicine may cause life-threatening respiratory depression. Close monitoring of respiratory function is recommended while using this medicine. Equipment for resuscitation should be immediately available if the injection form of this medicine is used.

Neonatal Opioid Withdrawal Syndrome

This medicine may cause life-threatening withdrawal symptoms in neonates born to women who were under prolonged therapy with Fortwin Injection 1 ml. Such neonates should be monitored closely for any unusual side effects. Appropriate corrective measures may be required based on the clinical condition.

Adrenal insufficiency

This medicine may cause adrenal insufficiency like other opioid medicines, hence caution is advised while using this medicine for more than one month. Any unusual symptoms should be reported to the doctor on priority. Appropriate corrective measures, gradual withdrawal of therapy, and replacement with a suitable alternative may be required based on the clinical condition.

Severe hypotension

Fortwin Injection 1 ml may cause severe hypotension while getting up from a lying or a sitting position. Patients are advised to get up slowly from a sitting or a lying position to avoid sudden hypotension, fainting, dizziness, etc. Report any unusual symptoms to the doctor immediately. Close monitoring of blood pressure, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of Fortwin Injection 1 ml therapy may cause withdrawal symptoms, especially after a prolonged use. Gradual tapering of dosage is recommended to avoid withdrawal symptoms.

Sports

Use of this medicine is prohibited at all times according to category S7 of World Anti-Dopping Agency (WADA).

Drowsiness

This medicine causes drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during treatment with this medicine.

Missed Dose

Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low. Tablets: This medicine is usually taken as required. If you are on a scheduled dosing of this medicine, take the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for the next scheduled dose.

Overdose

Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Tablets: Seek emergency medical treatment or contact the doctor immediately if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Alcohol should not be consumed while receiving this medicine since it may increase the risk of drowsiness, lightheadedness, impairment in thinking and judgment, etc. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Baclofen

Citalopram

Ondansetron

Tramadol

Alprazolam

Fentanyl

Alvimopan

Disease interactions

Impaired gastrointestinal function

Therapy with Fortwin Injection 1 ml should be administered cautiously in patients with impaired gastrointestinal function due to the increased risk of constipation, elevated intraluminal pressure, and spasm. Patients should be monitored closely for any adverse effects. Replacement with a suitable alternative may be required based on the clinical condition.

Infectious Diarrhea

Therapy with opioids should be avoided or administered cautiously in patients with infectious diarrhea, particularly that due to pseudomembranous enterocolitis or enterotoxin-producing bacteria or if accompanied by high fever, pus, or blood in the stool. Fortwin Injection 1 ml may prolong and/or worsen diarrhea.

Liver disease

Therapy with opioids should be administered cautiously and initiated at reduced dosages in patients with liver diseases due to the increased risk of severe adverse effects. Subsequent doses should be titrated based on individual response rather than a fixed dosing schedule.

Renal Dysfunction

Therapy with opioids should be administered cautiously and initiated at reduced dosages in patients with renal dysfunction due to the increased risk of severe adverse effects. Subsequent doses should be titrated based on individual response rather than a fixed dosing schedule.

Acute myocardial infarction

Opioid analgesics should be administered cautiously and only if the benefit of using this medicine outweighs the risks in patients with coronary insufficiency or acute myocardial infarction.

Intracranial pressure

Caution is advised while using this medicine in patients with a head injury, intracranial lesions, or pre-existing elevated CSF pressure due to the increased risk of cerebral hypoxia and vasodilation leading to increased intracranial pressure.

Respiratory Depression

Therapy with opioids should be administered cautiously and initiated at reduced dosages in patients with severe CNS or respiratory depression due to the increased risk of worsening of the patient's condition. Close monitoring of pulmonary function is recommended for such patients. Equipment for resuscitation should be immediately available if required.
Food interactions
Information not available.
Lab interactions
Information not available.
Injection: Fortwin Injection 1 ml is usually administered by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Consult the doctor if you experience any undesirable side effects. Tablets: Take Fortwin Injection 1 ml as instructed by your doctor. Do not take in larger quantities than advised/prescribed. Do not share this medicine with others. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
Fortwin Injection 1 ml blocks the pain signals from reaching the brain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Narcotic analgesics, Mixed opioid receptor agonists-antagonists

Schedule

Schedule H

Pentazocine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601092.html

DailyMed - Talwin- pentazocine lactate injection, solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3107d8eb-ebe8-4114-9db0-2d278612f186

[Internet]. 2017 [cited 30 August 2017]. Available from:

https://www.medicines.org.uk/emc/PIL.18130.latest.pdf

Pentazocine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00652

Toxnet [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~PfEUFT:5

Pentazocine (substance) [Internet]. Snomedbrowser.com. 2017 [cited 30 August 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/387213004
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