Home >
Medicine Info >
Folitrax 15 MG Injection
Loading interface...

Folitrax 15 MG Injection

Manufactured byIpca Laboratories Pvt. Ltd.
ContainsMethotrexate
Description
Folitrax 15 MG Injection is used for the treatment of life-threatening conditions like severe rheumatoid arthritis, psoriasis, and certain types of cancers. It should be used under the supervision of a qualified professional. It may cause severe liver, kidney and lung injury if taken in more quantities. Close monitoring of blood cell count is necessary.
QUICK LINKS:
Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Folitrax 15 MG Injection

Biotrexate 15 MG Injection
Zydus Cadila
Imutrex 15 MG Injection
Cipla Ltd.
Mexate 15 MG Injection
Zydus Cadila
Remtrex 15 MG Injection
Alkem Laboratories Ltd.

Side effects

Major & minor side effects for Folitrax 15 MG Injection

  • Diarrhea
  • Joint pain
  • Abdominal pain
  • Swelling of feet or lower legs
  • Dizziness
  • Fever with chills
  • Unusual bleeding
  • Blurred vision
  • Hair loss
  • Loss of appetite
  • Nausea or Vomiting
  • Pale skin
  • Skin rash
  • Pain at the injection site

Uses of Folitrax 15 MG Injection

What is it prescribed for?

  • Acute Lymphoblastic Leukemia
  • Choriocarcinoma
  • Meningeal Leukemia
  • Breast cancer
  • Psoriasis
  • Rheumatoid Arthritis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended due to the risk of liver injury. Close monitoring of liver enzymes is necessary. Seek immediate medical treatment if any symptoms like lethargy, yellow-colored eyes, and skin, abdominal pain appear.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for pregnant women.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to methotrexate, or any other inactive ingredients present along with the formulation.

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of birth defects.

Liver disease

This medicine is not recommended for use in patients with severe liver impairment and alcoholic liver disease due to the increased risk of worsening the patient's condition.

Blood disorder

This medicine is not recommended for use in patients with blood diseases such as anemia, bone marrow hypoplasia, leukopenia (low white blood cell count), thrombocytopenia (low platelet count), etc. due to the increased risk of worsening the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Bonemarrow suppression

This medicine should be used with extreme caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or operating machinery

Use of this medicine may cause dizziness, tiredness, drowsiness, blurred vision, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Lung toxicity

This medicine may cause severe lung injuries like pulmonary fibrosis, pulmonary interstitial infiltrates. Any symptoms of breathing difficulty and signs of lung impairment should be informed to the doctor. The treatment should be discontinued if any symptoms appear.

Skin reactions

The medicine may cause severe skin reactions such as stevens-johnson syndrome, skin necrosis, and skin ulceration. Inform the doctor if any symptoms appear. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Gastrointestinal injury

This medicine should be used with extreme caution in patients suffering from gastrointestinal disorders such as peptic ulcer disease or ulcerative colitis due to the increased risk of worsening of the patient's condition. Inform the doctor if you have any gastrointestinal disorders before initiation of the therapy. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Infections

Use of this medicine may weaken the immune system and make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while receiving this medicine. Any signs and symptoms of infection such as a sore throat, fever, chills, etc. should be reported to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended due to the risk of liver injury. Close monitoring of liver enzymes is necessary. Seek immediate medical treatment if any symptoms like lethargy, yellow-colored eyes, and skin, abdominal pain appear.
Interaction with Medicine

Azole antifungal agents

Atorvastatin

Live attenuated vaccines and related products

Proton pump inhibitors

Disease interactions

Liver Disease

This medicine is not recommended for use in patients with severe liver impairment and alcoholic liver disease due to the increased risk of worsening the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Kidney disease

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by interfering the DNA synthesis and stops the growth of the cells.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Other immunosuppressant, Antimetabolites, Antipsoriatics, Antirheumatics

Schedule

Schedule H

Methotrexate 100 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2019 [cited 26 September 2019]. Available from:

https://www.medicines.org.uk/emc/product/6756

Methotrexate Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 26 September 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a682018.html

DailyMed - Methotrexate- methotrexate sodium injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 26 September 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ec476b11-0b3c-4139-b1eb-a3daa76bc271

Methotrexate - DrugBank [Internet]. Drugbank.ca. 2019 [cited 26 September 2019]. Available from:

https://www.drugbank.ca/drugs/DB00563
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 26 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.