Flutamide

Description

Flutamide is a non-steroidal anti-cancer medicine used in men along with other specific agents for the treatment of prostate cancer. This medicine is not recommended for use in females, children, and adolescents.

Side effects

Major & minor side effects for Flutamide

  • Increased appetite
  • Sleeplessnes
  • Anxiety
  • Blurred vision
  • Cough
  • Stomach upset
  • Tiredness
  • Chest pain

Uses of Flutamide

What is it prescribed for?

  • Prostate Cancer
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to Flutamide or any other inactive ingredients present along with it.

Severe Hepatic impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Cardiovascular Disorders

This medicine should be used with caution in patients with heart disorders due to the increased risk of worsening of the patient's condition. Regular monitoring of the clinical condition is necessary while receiving this medicine. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients suffering from mild to moderate liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe liver impairment.

Kidney impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in females children, and adolescents

This medicine is not recommended for use in females, children, and adolescents.

Aniline toxicity

Therapy with this medicine may cause aniline toxicity and may cause adverse effects in some patients, especially who are sensitive to aniline toxicity. Appropriate corrective measures, dose adjustment, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Pimozide

Leflunomide

Lomitapide

Clozapine

Amiodarone

Disease interactions

Liver impairment

This medicine should be used with caution in patients suffering from mild to moderate liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. This medicine is not recommended for use in patients with severe liver impairment.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by blocking the action of male hormones on the prostate gland, thereby stopping the growth and spread of cancer cells.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antiandrogens, Hormones/antineoplastics

Schedule

Schedule H

Flutamide - DrugBank [Internet]. Drugbank.ca. 2018 [cited 5 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB00499

Flutamide 250 mg Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 5 December 2018]. Available from:

https://www.medicines.org.uk/emc/product/8428#

Flutamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 5 December 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a697045.html

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 5 December 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-04981-3&d=201812051016933

Cytomid Tablets [Internet]. CiplaMed. 2019 [cited 25 March 2019]. Available from:

https://ciplamed.com/content/cytomid-tablets

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Information on this page was last updated on 25 Mar 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.