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Flanzen-DP Tablet
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Flanzen-DP Tablet

Manufactured byMANEESH PHARMACEUTICALS LTD
ContainsDiclofenac (50 mg) + Paracetamol (500 mg) + Serratiopeptidase (10 mg)
Description
Flanzen-DP Tablet is a combination medicine that may be used to relieve symptoms such as fever, mild to moderate pain, swelling, redness, etc. associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, headache, toothache, surgeries, etc. This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Flanzen-DP Tablet

  • Diarrhea
  • Nausea or Vomiting
  • Bloody and Cloudy urine
  • Tiredness and weakness
  • Abdominal pain or stomach pain
  • Constipation
  • Skin Rash
  • Unusual bleeding or bruising
  • Gastric / Mouth Ulcer

Uses of Flanzen-DP Tablet

What is it prescribed for?

  • Mild to Moderate pain
  • Inflammation and edema
  • Dysmenorrhea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 10-30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to diclofenac, paracetamol, serratiopeptidase, other proteolytic enzymes, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients suffering from severe impairment of liver function due to the increased risk of worsening of the patient's condition.

NSAID-induced asthma

This medicine is not recommended for use in patients suffering from NSAID-sensitive asthma due to the increased risk of worsening of the patient's condition.

Gastrointestinal bleeding

This medicine is not recommended for use in patients with a known history of gastrointestinal bleeding due to the increased risk of worsening of the patient's condition.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG) (Heart surgery)

This medicine is not recommended for use before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Overdose

Read the label carefully before consuming this medicine to avoid overdosage. An overdose of this medicine may cause liver damage. Seek emergency medical attention if an overdose of this medicine is suspected.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Long term use

Use of this medicine for more than 4 weeks is not advised since the safety and efficacy of long-term use are not clinically established.

Bleeding disorders

This medicine should be used with extreme caution in patients with any bleeding disorders due to the increased risk of excessive bleeding. Report any unusual bruising or bleeding to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Surgeries

The use of this medicine should be stopped at least 10-14 days before a scheduled surgery as it may increase the risk of bleeding during and/or after the procedure.

Gastro-intestinal toxicity

Use of this medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. This risk is especially higher in patients with a history of gastrointestinal diseases. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Diseases

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Fluid retention and Edema

Use of this medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Skin allergies

Use of this medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
Interaction with Medicine

Carbamazepine

Phenytoin

Leflunomide

Adefovir

Methotrexate

Ketorolac

Apixaban

Aspirin

Disease interactions

Alcoholism

This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Bleeding disorders

This medicine should be used with extreme caution in patients with any bleeding disorders due to the increased risk of excessive bleeding. Report any unusual bruising or bleeding to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Do not take this medicine for longer durations than recommended. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Diclofenac works by reducing the formation of certain substances in the body that are responsible for causing pain and swelling. Paracetamol increases the pain threshold and decreases swelling; it also brings down elevated body temperature. Serratiopeptidase reduces redness and swelling through the breakdown of proteins present at the site of swelling.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Miscellaneous analgesics

Schedule

Schedule H

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Serrapeptase | Ca7Zn+16 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 13 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/72941625#section=Top

Diclofenac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 6 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689002.html

Diclofenac | C14H11Cl2NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 23 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3033
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Information on this page was last updated on 2 Jul 2019

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