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Fabiflu Tablet
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Fabiflu Tablet

Manufactured byGLENMARK PHARMACEUTICALS LTD
ContainsFavipiravir
Description
Fabiflu Tablet is an antiviral medicine that is used to treat mild to moderate cases of coronavirus (COVID-19) infections. COVID-19 infection is highly contagious and is caused by the SARS CoV-2 virus. The common symptoms of COVID-19 include fever, cough, loss of taste or smell, breathing difficulty, nasal congestion, and diarrhoea. Fabiflu Tablet prevents the virus from multiplying in the body. Since 2014, this medicine is approved in Japan to treat cases of influenza that are unresponsive to conventional treatment. Fabiflu Tablet may cause side effects like diarrhoea, decrease in white blood cell count (especially neutrophils), increase in blood uric acid levels, and elevated liver enzyme levels. Consult your doctor if your diarrhoea worsens or if you are concerned about the side effects. Do not discontinue this medicine without consulting your doctor. Seek immediate medical attention if you see signs of allergic reactions like hives, skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, etc. Fabiflu Tablet may be taken with or without food, but taking it with or after a meal may help prevent side effects like nausea and vomiting. Take Fabiflu Tablet at the same time every day for better results and compliance (so you do not forget). Fabiflu Tablet is not recommended for use if you are pregnant or are breastfeeding due to the lack of safety and efficacy data. Inform your doctor if you have gout (a condition that causes severe pain, redness, and tenderness in the joints) or any liver, kidney, or heart problems before starting treatment with this medicine. Use in children is not recommended due to the lack of sufficient safety and efficacy data.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Fabiflu Tablet

Favtris 200 Tablet
Mylan Pharmaceuticals

Side effects

Major & minor side effects for Fabiflu Tablet

  • Increased blood uric acid levels
  • Diarrhoea
  • Dizziness
  • Elevated Liver Enzymes
  • Neutropenia

Uses of Fabiflu Tablet

What is it prescribed for?

  • Coronavirus Disease (COVID-19)
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Fabiflu Tablet to show its action has not been clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Fabiflu Tablet remains active in the body has not been clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Fabiflu Tablet.
  • Can this medicine be taken during pregnancy?
    Fabiflu Tablet is not recommended for use in pregnant women. Consult your doctor before starting treatment with this medicine if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Fabiflu Tablet is not recommended for use in breastfeeding women. Consult your doctor before starting treatment with this medicine if you are breastfeeding.

Allergic reaction

Fabiflu Tablet is not recommended for use if you are allergic to Favipiravir or any other ingredient present in this medicine. Seek emergency medical assistance if you experience symptoms like hives, rashes, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, etc.
Warnings for special population

Pregnancy

Fabiflu Tablet is not recommended for use in pregnant women. Consult your doctor before starting treatment with this medicine if you are pregnant.

Breast-feeding

Fabiflu Tablet is not recommended for use in breastfeeding women. Consult your doctor before starting treatment with this medicine if you are breastfeeding.
General warnings

Hyperuricaemia

Fabiflu Tablet may increase the uric acid levels in the blood and hence should be used with extreme caution if you have hyperuricaemia (increased uric acid levels in the blood), gout, or a history of gout. Report any unusual symptoms such as pain, swelling, or stiffness in joints, difficulty in movement, etc. to your doctor immediately. Your doctor may recommend close monitoring of the blood uric acid levels, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative based on your clinical condition.

Kidney impairment

Fabiflu Tablet is not recommended for use if you have or had kidney problems as Favipiravir can cause kidney damage in some people. Inform your doctor of any kidney issues you may have before starting treatment with Fabiflu Tablet.

Liver impairment

Fabiflu Tablet is not recommended for use if you have or had liver problems. Favipiravir is processed in the liver which can lead to its accumulation in the body and decreased elimination in people with liver impairment. This can lead to the worsening of side effects caused by Favipiravir. Inform your doctor of any liver issues you may have before starting treatment with Fabiflu Tablet.

Use of contraception

Fabiflu Tablet is distributed in sperm. Your doctor may recommend the use of effective contraception like condoms during sexual intercourse to prevent the transfer of the medicine during and after seven days of treatment with Favipiravir.

Use in women of childbearing age

Fabiflu Tablet may be unsafe for use in pregnant women. Hence, your doctor may recommend taking a pregnancy test before starting treatment with Fabiflu Tablet.

Missed Dose

Avoid missing a scheduled dose of Fabiflu Tablet. Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one. If Fabiflu Tablet is used in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Seek emergency medical assistance or contact your doctor immediately in case of an overdose. If Fabiflu Tablet is used in the clinical/hospital setting, the likelihood of an overdose is very low. Emergency medical treatment will be initiated if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Repaglinide

Famciclovir

Pyrazinamide

Theophylline

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Follow your doctor's instructions when taking Fabiflu Tablet. It can be taken with or without food. Do not break, crush, or chew the tablet. Swallow as a whole. If Fabiflu Tablet is used in the clinical/hospital setting, it will be administered by a qualified healthcare professional. Do not take Fabiflu Tablet in larger or smaller amounts than prescribed. Consult your doctor in case of any undesirable effects that do not resolve with time. Do not stop taking Fabiflu Tablet before completion of the course. Consult your doctor if you wish to discontinue this medicine. Fabiflu Tablet is excreted in sperm in significant amounts. Make sure to use effective contraception like condoms during sexual intercourse to prevent the transfer of the medicine to your partner. Practice social distancing, wear protective equipment like masks, face shields, etc., and wash and sanitize your hands frequently to prevent the further spread of COVID-19 to others. Keep out of the reach of children and pets. Ensure that unused or expired medicine is disposed of properly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Fabiflu Tablet works by inhibiting an enzyme that is necessary for the virus to multiply. This helps in decreasing the viral load in your body and preventing the further spread of the infection.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antiviral agents, RNA Polymerase Inhibitors

Schedule

Schedule H

Cdc.gov.tw. 2017. Avigan英文仿單. [online] Available at: < [Accessed 7 December 2021].

https://www.cdc.gov.tw/File/Get/ht8jUiB_MI-aKnlwstwzvw>

Pubchem.ncbi.nlm.nih.gov. 2021. Favipiravir. [online] Available at: < [Accessed 7 December 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Favipiravir>

CiplaMed. 2020. CIPLENZA Tablets. [online] Available at: < [Accessed 7 December 2021].

https://www.ciplamed.com/content/ciplenza-tablets>

Clinicaltrials.gov. 2020. Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh - ClinicalTrials.gov. [online] Available at: < [Accessed 7 December 2021].

https://clinicaltrials.gov/ct2/show/NCT04402203>
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Information on this page was last updated on 17 Jan 2022

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