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EUGEST 400 CAPSULE

Manufactured bySamarth Life Sciences Pvt. Ltd.
Description
EUGEST 400 CAPSULE contains a female hormone (chemical messenger) called Progesterone. It is used to treat problems related to hormonal imbalance. This includes menstrual-related problems like secondary amenorrhea (absence of three or more periods in a row) and pregnancy-related problems. EUGEST 400 CAPSULE is used along with another hormone called estrogen to prevent endometrial hyperplasia (overgrowth or thickening of the lining of the uterus/womb) and symptoms of menopause (end of the menstrual cycle). This medicine is used in hormone replacement therapy as it helps to increase the levels of progesterone hormone in your body. You may experience certain side effects of EUGEST 400 CAPSULE such as nausea, headache, abnormal vaginal discharge, stomach pain, dizziness, diarrhoea or constipation, etc. These symptoms are usually seen during the first few weeks of therapy and generally decrease as your body adjusts to the medication. Never use EUGEST 400 CAPSULE if you are previously allergic to it. Take EUGEST 400 CAPSULE with food. Take it at the same time every day to avoid any missed dose. The dose and duration of this medicine will be prescribed by the doctor based on your condition. Before taking EUGEST 400 CAPSULE, inform your doctor if you have/had breast cancer, unusual bleeding in the vagina or liver disease. Your doctor will probably advise you on a few diagnostic tests before starting the treatment.

Side effects

Major & minor side effects for EUGEST 400 CAPSULE

  • Headache
  • Mood swings
  • Vaginal discharge
  • Breast pain and tenderness
  • Muscle or joint pain
  • Constipation
  • Depression
  • Breast lumps
  • Loss of vision or blurred vision
  • Unexpected vaginal bleeding
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Nausea or Vomiting

Uses of EUGEST 400 CAPSULE

What is it prescribed for?

  • Endometrial hyperplasia
  • Secondary Amenorrhoea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The duration for which EUGEST 400 CAPSULE may show its action varies from one person to another. It also differs based on the indication it is used for and levels of other sex hormones in your body.
  • How long do the effects of this medicine last?
    The duration of EUGEST 400 CAPSULE that remains active varies based on factors like age, dosage form etc.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported for EUGEST 400 CAPSULE.
  • Can this medicine be taken during pregnancy?
    According to some human research, it was seen that EUGEST 400 CAPSULE cause no harm to your foetus. However, it may cause when used along with estrogen. Hence, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    EUGEST 400 CAPSULE can pass through your milk. However, the effects of this medicine on infants is not known. Hence it is advised to inform your doctor if you are breastfeeding.

Allergy

EUGEST 400 CAPSULE is not recommended for use if you have a known allergy to progesterone or other progestin analogues (synthetic hormones that act in a similar way as progesterone), or any other inactive ingredients of this medicine. Seek an immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Abnormal vaginal bleeding

EUGEST 400 CAPSULE is not recommended for use if you have an abnormal vaginal bleeding episode that has not been diagnosed by a doctor. If you have any menstrual abnormalities, report them to your doctor immediately.

Breast cancer

If you have or suspect having breast cancer, avoid EUGEST 400 CAPSULE as it may worsen your condition. Before taking this medicine, inform your doctor if you have a family history of breast cancer. Your doctor will monitor you properly during the treatment with this medicine. It is also not recommended for use if you have or suspect hormone-related cancer [such as the cancer of the uterus (womb) or other sex organs].

Miscarriage

Avoid using EUGEST 400 CAPSULE if you had an incomplete miscarriage or missed abortion (foetus is not alive and present inside the uterus) recently, as it may cause serious adverse effects and worsen your health condition.

Heart and blood vessel disorder

Avoid using EUGEST 400 CAPSULE if you have an active or historic instance of stroke (brain damage due to blocked blood flow), heart attack or clotting disorder. Using this medicine increases the risk of blood coagulation which may worsen your condition. Inform the doctor about your medical history before taking this medicine.

Liver disease

EUGEST 400 CAPSULE is metabolised in the liver and improper liver function can lead to its accumulation. Avoid this medicine if you have severe impairment of liver function. If you notice any signs of jaundice (like yellowish discolouration of skin and eyes) or other liver-related problems, discontinue the use of this medicine and inform your doctor.

Asthma

EUGEST 400 CAPSULE should be cautiously used if there is Asthma (airways in your lungs become narrow and swollen) as it can lead to fluid retention and worsen the condition.
Warnings for special population

Pregnancy

According to some human research, it was seen that EUGEST 400 CAPSULE cause no harm to your foetus. However, it may cause when used along with estrogen. Hence, consult your doctor before taking this medicine.

Breast-feeding

EUGEST 400 CAPSULE can pass through your milk. However, the effects of this medicine on infants is not known. Hence it is advised to inform your doctor if you are breastfeeding.
General warnings

Dizziness and drowsiness

EUGEST 400 CAPSULE may cause dizziness or drowsiness, hence do not drive or operate heavy machinery if you experience any of these symptoms. Consult with your doctor if these symptoms persist.

Vision abnormalities

EUGEST 400 CAPSULE may cause vision problems like blurred or double vision, or loss of vision. Inform your doctor immediately if you experience these vision problems, also do not drive or operate heavy machinery.

Other medicines

It is recommended to report the use of all your current medicines including supplements and herbs to your doctor before receiving EUGEST 400 CAPSULE.

Peanut allergy

EUGEST 400 CAPSULE preparation may contain peanut oil in it. Hence avoid using it if you have a known allergy to peanuts.

Missed Dose

If you forgot to take the dose of EUGEST 400 CAPSULE at a given time, then take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose of EUGEST 400 CAPSULE. An overdose of this medication can cause some serious effects on the heart, blood vessels, and nerve conduction. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Ketoconazole

Insulin

Phenobarbital

Disease interactions

Thromboembolism

Thromboembolism is a condition in which a blood clot is dislodged from another location in the circulation and causes obstruction in the blood flow. EUGEST 400 CAPSULE when used in high doses can cause blood clot formation and may worsen your condition.

Depression

Depression is a disorder that affects your mood and may cause a loss of interest in other activities. EUGEST 400 CAPSULE should be used with caution if you are diagnosed with depression or other psychiatric disorders as it may cause hallucinations, aggressiveness, mood swings, suicidal thoughts and other behavioural changes.

Retinal thrombosis

Retinal thrombosis is an eye condition that results in blood clot formation in the vein in the retina. It is a painless disease and causes blurring or loss of eyesight. It usually always occurs in only one eye. Use EUGEST 400 CAPSULE with caution if you have retinal thrombosis as it may cause side effects such as loss of vision, blurred vision, or retinal vascular lesions. This risk is especially high if you have a history of vision problems or have active vision problems.

Fluid Retention and edema

EUGEST 400 CAPSULE can cause fluid retention and oedema especially when used for a long period. Use it with caution if you have a history of excess fluid retention.

Hyperlipidemia

EUGEST 400 CAPSULE should be used with extreme caution if you are diagnosed with hyperlipidemia (increased fat levels in the blood) as it may increase the fat deposits and worsen your condition.
Food interactions
Grapefruit juice can interact with EUGEST 400 CAPSULE and increases the progesterone levels in the body. This leads to side effects like headache, breast tenderness and altered vaginal bleeding patterns.
Lab interactions

Blood coagulation tests

Report the use of EUGEST 400 CAPSULE to your doctor before undergoing a test to measure the coagulation time. The use of this medicine may interfere with the test results.

Thyroid function tests

EUGEST 400 CAPSULE is known to give a false-positive result for thyroid function tests. Hence inform your lab technician or doctor about its use.
Follow all the instructions advised by your physician while taking EUGEST 400 CAPSULE orally. Do not take this medicine in larger or smaller quantities than advised. Regular follow-ups with the doctor during treatment and also regular breast exams are necessary to observe for the presence of lumps while using this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
EUGEST 400 CAPSULE treats infertility by regulating menstrual periods in women with secondary amenorrhoea (absence of a menstrual period for three or more months). This medicine maintains pregnancy by preparing the uterine (womb) lining to accommodate a fertilised egg (which develops into a foetus).
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Progestins

Schedule

Schedule H

Progesterone [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 7 February 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Progesterone

Progesterone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 7 February 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a604017.html

[Internet]. Accessdata.fda.gov. 2020 [cited 10 February 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019781s017,020843s011lbl.pdf

Utrogestan 100mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 10 February 2020]. Available from:

https://www.medicines.org.uk/emc/product/352/smpc

www.pdr.net. (n.d.). Progesterone (progesterone) dose, indications, adverse effects, interactions... from PDR.net. [online] Available at: [Accessed 17 Aug. 2021]. ‌

https://www.pdr.net/drug-summary/progesterone?druglabelid=2388
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Information on this page was last updated on 17 Aug 2021

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