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Etoshine MR Tablet
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Etoshine MR Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsEtoricoxib (60 mg) + Thiocolchicoside (4 mg)
Description
Etoshine MR Tablet is a combination of Etoricoxib and Thiocolchicoside. It is a painkiller medicine that provides relief from pain and swelling associated with muscle spasms such as low back pain, neck pain, sprains/strains, etc. It works by relaxing your muscles and preventing muscle contraction. It also prevents the release of a chemical substance that causes pain and swelling in your body. Etoshine MR Tablet has side effects such as increased blood pressure, headache, stomach pain, heartburn, and diarrhoea. These side effects usually subside by themselves. However, consult your doctor if they remain for a long time or worsen. As this medicine may cause dizziness and drowsiness, avoid driving vehicles or operating heavy machines. Etoshine MR Tablet dose and duration of treatment will be determined by your doctor based on your condition. Take this medicine as instructed by your doctor. Avoid taking more or less than the prescribed dose. For the ease of remembering and better results, take it at the same time every day. Take this medicine for the complete duration of treatment and avoid discontinuation without consulting your doctor as your symptoms may reappear. Etoshine MR Tablet is not recommended for use if you are allergic to it. Avoid taking this medicine if you have severe liver or kidney problems, or existing heart problems. Use this medicine with caution if you have diabetes and/or high blood cholesterol levels. Etoshine MR Tablet is not recommended for use in children below 16 years of age. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before taking this medicine.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Etoshine MR Tablet

Dorfree MR 4 Tablet
Lupin Ltd.

Side effects

Major & minor side effects for Etoshine MR Tablet

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Nausea and Vomiting
  • Yellowing of skin and eyes
  • Dry mouth
  • Headache
  • Diarrhoea
  • Dizziness
  • Stomach pain
  • Blurred vision
  • Heart burn
  • Loss of appetite
  • Increase in blood pressure
  • Drowsiness

Uses of Etoshine MR Tablet

What is it prescribed for?

  • Relief from pain and swelling
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Etoshine MR Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Etoshine MR Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Etoshine MR Tablet.
  • Can this medicine be taken during pregnancy?
    Etoshine MR Tablet is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Etoshine MR Tablet is not recommended for use in breastfeeding as it may pass into breastmilk. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Etoshine MR Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Peptic Ulcer

Etoshine MR Tablet can cause stomach and intestinal bleeding. Therefore, this medicine is not recommended for use if you have peptic ulcers (sores in the lining of the stomach, small intestine, and food pipe) or bleeding in the stomach and intestine as it may worsen your health condition.

Severe Liver/Kidney Impairment

Etoshine MR Tablet is not recommended for use if you have severe liver and/or kidney problems. This medicine may further damage your liver and/or kidneys and worsen your condition.

Heart diseases

Etoshine MR Tablet is not recommended for use if you have heart problems such as heart failure (a condition in which your heart is unable to pump a sufficient amount of blood), ischaemic heart diseases (heart problems due to narrowing of the blood vessels that supply oxygen to the heart), high blood pressure that has not been adequately controlled or if you have undergone a coronary artery bypass graft surgery (a surgical procedure that diverts the blood from narrowed or blocked vessels in the heart to improve its blood supply). Taking this medicine may increase your risk of heart attack and stroke (a condition that occurs due to reduced blood supply to the brain).
Warnings for special population

Pregnancy

Etoshine MR Tablet is not recommended for use during pregnancy as it may cause harm to your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Etoshine MR Tablet is not recommended for use in breastfeeding as it may pass into breastmilk. Consult your doctor if you are breastfeeding.
General warnings

High blood pressure

Etoshine MR Tablet can cause an increase in blood pressure. Hence, this medicine should be used with caution if you have high blood pressure as it may worsen your health condition. Keep a regular check of your blood pressure while taking this medicine.

Dehydration

Etoshine MR Tablet should be used with caution if you are dehydrated as it may worsen your condition. Your doctor may correct such conditions first before starting the treatment.

Infections

Etoshine MR Tablet should be used with caution if you have any infection since it may mask the symptoms of an infection such as a fever.

Diabetes

Etoshine MR Tablet should be used with caution if you have diabetes (a condition of high sugar levels in your blood) or high cholesterol (fat) levels as it may increase the risk of heart problems. Consult your doctor before taking this medicine.

Use in children

Etoshine MR Tablet is not recommended for use in children below 16 years of age as the safety and efficacy data are not clinically established.

Oral contraceptive medicines

Avoid using birth control pills containing Ethinyl Estradiol along with Etoshine MR Tablet as it may increase the risk of side effects.

Other medicines

Etoshine MR Tablet may interact with many other medicines and may cause severe side effects. Hence, inform your doctor about all your current medicines including any herbs and supplements before starting the treatment.

Driving or operating machines

Etoshine MR Tablet may cause sleepiness, blurred vision, or dizziness in some cases. Hence, avoid driving vehicles and/or operating heavy machines if you experience such symptoms.

Impairment of fertility in men

Etoshine MR Tablet may cause damage to sperm cells and lead to fertility problems in men. Therefore, discuss all the risks and benefits with your doctor before taking this medicine.

Use in women of childbearing potential

Women of childbearing potential should use effective contraceptive measures to avoid pregnancy during treatment with Etoshine MR Tablet. A pregnancy test should be done to rule out pregnancy before beginning the treatment. If pregnancy is suspected during treatment, consult your doctor for further guidance.

Missed Dose

Try not to skip the scheduled dose of Etoshine MR Tablet. If you miss a dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Never take more than the prescribed dose of Etoshine MR Tablet. Seek emergency medical attention in case of overdose for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Lithium

Ramipril

Warfarin

Ethinyl Estradiol

Rifampicin

Disease interactions

Fluid Retention and oedema

Etoshine MR Tablet may cause fluid retention (abnormal build-up of fluid in the body) and lead to swelling of the legs and feet. Etoshine MR Tablet should be used with caution in such conditions as it may further increase the risk of heart problems. Keep a regular check of your blood pressure and heart functions while taking this medicine.

Heart Disease

Etoshine MR Tablet should be used with caution if you have a history of heart problems as this medicine may cause heart attack and stroke. Report any incidence of heart problems to your doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Liver Disease

Etoshine MR Tablet is broken down in your liver. Hence, this medicine should be used with caution if you have liver problems as it may lead to the accumulation of this medicine in your body and increase the risk of side effects. It may also cause further liver damage. Your doctor may suggest tests to closely monitor your liver function and liver enzyme levels while taking this medicine.

Kidney Disease

Etoshine MR Tablet should be used with caution if you have kidney problems as this medicine may further damage your kidneys. Your doctor may suggest tests to monitor your kidney function while taking this medicine.

Stomach ulcers or bleeding

Etoshine MR Tablet should be used with caution as it may cause damage to the linings of your stomach and intestine. Conditions like bleeding, ulceration (sores in the lining of your stomach and intestine), and perforation (holes that form in the walls of the stomach and intestine) can occur. If you experience symptoms like indigestion, vomit with blood, or appearance of coffee-coloured dry blood in the stools, etc. consult your doctor immediately.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Etoshine MR Tablet with or without food as instructed by your doctor. Never take more than the prescribed dose. Take this medicine at the same time every day for ease of remembering. Consult your doctor if your symptoms do not improve or become more severe.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Etoshine MR Tablet is a combination of Etoricoxib and Thiocolchicoside. Etoricoxib works by reducing the formation of certain substances in your body that cause pain and swelling. Thiocolchicoside is a muscle relaxant. It works in the brain and spinal cord to prevent muscle contractions and relieve muscle spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Muscle relaxants, Analgesics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Thiocolchicoside. [online] Available at: < [Accessed 12 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Thiocolchicoside>

Pubchem.ncbi.nlm.nih.gov. 2021. Etoricoxib. [online] Available at: < [Accessed 17 June 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Etoricoxib>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 2 September 2021].

https://www.medicines.org.uk/emc/files/pil.669.pdf>

Stewart, M., 2021. Etoricoxib. Etoricoxib tablets and side effects at Patient. [online] Patient.info. Available at: <o/medicine/etoricoxib-for-pain-and-inflammation-arcoxia> [Accessed 2 September 2021].

https://patient.inf

Iasispharma.com. 2021. [online] Available at: < [Accessed 24 August 2021].

https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf>
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Information on this page was last updated on 14 Mar 2022

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