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Etogesic P (500/400 mg) Tablet

Manufactured byZydus Cadila
ContainsParacetamol (500 mg) + Etodolac (400 mg)
Description
Etogesic P (500/400 mg) Tablet is a combination medicine used to relieve mild to moderate pain such as a headache, toothache, muscle pain, and arthritic pain. Close monitoring of kidney and liver function is recommended during treatment with this medicine.

Side effects

Major & minor side effects for Etogesic P (500/400 mg) Tablet

  • Nausea and vomiting
  • Fever
  • Allergic skin reaction
  • Gastric Ulcer
  • Bloody and cloudy urine
  • Anemia
  • Stevens-Johnson Syndrome
  • Stomach pain
  • Diarrhea
  • Blurred vision
  • Ringing or buzzing in the ears
  • Sneezing

Uses of Etogesic P (500/400 mg) Tablet

What is it prescribed for?

  • Fever and Pain
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Mild to Moderate pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.

Allergy

This medicine is not recommended for use in patients with a known allergy to etodolac, any other NSAIDs, paracetamol, or any other inactive ingredient present along with these medicines.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers.

Liver Disease

This medicine is not recommended for use in patients suffering from liver diseases due to the increased risk of serious adverse effects.

Asthma

This medicine is not recommended for use in patients with asthma caused by aspirin or other non-steroidal anti-inflammatory drugs since it may worsen the patient's condition.

Gastrointestinal disorders

This medicine is not recommended for use in patients with gastrointestinal bleeding disorders or active peptic ulcers since it may worsen the patient's condition.

Heart surgery

This medicine is not recommended for use in relieving pain before or after a heart surgery due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women since the safety and efficacy of use are not clinically established.
General warnings

Overdose

This medicine is available in the market in various dosage forms. Read the label carefully before consuming this medicine to avoid overdosage. Overdose may result in liver damage. Seek emergency medical attention if an overdose of this medicine is suspected.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Skin rash

This medicine may cause serious skin allergies without any warnings. These events may be fatal in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor immediately. The treatment should be discontinued if these symptoms appear.

Geriatric use

This medicine should be used with caution in elderly population due to an increase in the risk of undesired side effects. Close monitoring of kidney function and symptoms of bleeding is recommended for such patients. Appropriate dose adjustments may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
Interaction with Medicine

Carbamazepine

Phenytoin

Ramipril

Warfarin

Sodium Nitrite

Leflunomide

Prilocaine

Ketorolac

Prednisolone

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Heart Disease

This medicine should be used with caution in patients with heart diseases due to the increase in the risk of fluid accumulation in the body. Inform the doctor if you have any heart diseases before receiving this medicine. The dose of the medicine may be reduced or an alternate treatment option may be considered based on the clinical condition.

Impaired kidney function

This medicine should be used with caution due to an increase in the risk of kidney injury. Close monitoring of kidney function is necessary while receiving this medicine. The dose of the medicine may be reduced or an alternate treatment option may be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Etodolac works by preventing the formation of chemical substances in the body which cause pain and swelling. Paracetamol increases the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Analgesic combinations, Analgesic antipyretic combinations

Schedule

Schedule H

[Internet]. 2017 [cited 27 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/27532

DailyMed - Etodolac tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=107ea9d7-80a9-41a4-b61e-168370127319

Etodolac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692015.html

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983

[Internet]. 2017 [cited 23 June 2017]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/acetaminophen.pdf
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Information on this page was last updated on 29 Sep 2017

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