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Etizola Plus 10 Tablet
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Etizola Plus 10 Tablet

Manufactured byMACLEODS PHARMACEUTICALS PVT LTD
ContainsEtizolam (0.5 mg) + Escitalopram (10 mg)
Description
Etizola Plus 10 Tablet is a combination medicine which may be used to treat central nervous system disorders like anxiety, insomnia (sleeplessness), depression, etc. Do not stop taking this medicine suddenly as it may cause withdrawal symptoms like mood changes, irritability, dizziness, numbness in the hands or feet, and difficulty in falling asleep.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Etizola Plus 10 Tablet

  • Drowsiness
  • Muscle weakness
  • Loss of balance control
  • Headache
  • Confusion
  • Slurred speech
  • Increase/decrease in libido (Increased or decreased sexual drive)
  • Uncontrolled shaking of arms or legs
  • Visual disturbances
  • Urinary retention/incontinence
  • Stomach discomfort and pain
  • Excessive salivation
  • Memory problems
  • Fast or irregular heartbeat
  • Reduced hunger
  • Constipation
  • Diarrhea
  • Dry mouth
  • Excessive air or gas in stomach
  • Decreased appetite
  • Joint pain

Uses of Etizola Plus 10 Tablet

What is it prescribed for?

  • Anxiety
  • Insomnia (Sleeplessness)
  • Depression
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30-60 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for a duration of 4 to 5 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious adverse effects. These side effects may include dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    Use of this medicine may cause habit-forming tendencies in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to etizolam, escitalopram, other SSRIs, or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors

This medicine is not recommended for use in patients undergoing treatment with Monoamine Oxidase Inhibitors (MAOIs) such as selegiline, moclobemide, etc. There should be a time gap of at least 14 days between stopping treatment with MAOIs and beginning treatment with this medicine to avoid their interaction.

Pimozide

This medicine is not recommended for use in patients undergoing treatment with pimozide due to increased risk of heart rhythm disorders.

Myasthenia gravis

This medicine is not recommended for use if you have a neuromuscular condition where the muscles tire rapidly, causing severe weakness and other complications due to the increased risk of worsening of the patient's condition.

Narrow angle glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Porphyria

This medicine is not recommended for use if you have this rare disease of the blood due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. Patients should be closely monitored for any change in mood or behavior. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Impaired Liver/Kidney function

This medicine should be used with caution in patients with kidney or liver diseases due to the increased risk of adverse effects. Close monitoring of kidney/liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Drug Abuse

This medicine should be used with caution in patients with a known history of drug abuse. Chances of dependency are very high, especially if the intended use is for a long duration of time. Patients should be monitored closely for any changes in mood and behavior and any drug-seeking behavior; any such changes should be reported to the doctor immediately.

Use in the elderly

This medicine should be used with caution in the elderly and bedridden patients as the risk of adverse effects are higher than normal patients.

Personality disorder

This medicine should be used with caution in patients having personality disorders or Organic brain syndrome due to the increased risk of adverse effects. An alternative treatment option should be considered in some cases based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Bleeding disorders

This medicine may increase the risk of abnormal bleeding in some patients. This risk is especially higher in patients with a history of bleeding disorders and patients undergoing treatment with aspirin, NSAIDs, anticoagulants, etc. Report any unusual bleeding or bruising, blood in the stool, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious adverse effects. These side effects may include dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Cetirizine

Cisapride

Clarithromycin

Clozapine

Ketoconazole

Metoclopramide

sulfonylureas

Diuretics

Disulfiram

Clonidine

Disease interactions

Glaucoma

This medicine should be used with caution in patients with a known history of glaucoma (increased intra-ocular pressure in the eye), due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Pulmonary insufficiency

This medicine should be used with caution in patients having a condition where a sufficient amount of blood is not reaching the lungs from the heart. The risk of severe to fatal breathing complications is high if this medicine is used in such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Depression

This medicine should be used with caution in patients with depression as it may worsen the symptoms. Close monitoring of symptoms like changes in the behavior and suicidal thoughts is necessary. Discontinue the medicine if symptoms persist.

Seizure disorders

This medicine should be used with extreme caution in patients with seizure disorders due to the increased risk of recurrent seizures. Treatment should be discontinued if the patient develops seizures or if there is an increase in the frequency of seizures in patients with a previous diagnosis of epilepsy. An alternative treatment option should be considered in such cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Etizolam works by binding to certain specific receptors in the brain causing relaxation and sleepiness. Escitalopram works by increasing the amount of a chemical substance in the brain which helps in maintaining the psychological balance.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Benzodiazepine derivatives, Thienodiazepine anxiolytics, Selective serotonin reuptake inhibitors

Schedule

Schedule H

Etizolam - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB09166

Etizolam | C17H15ClN4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 13 June 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/3307

Etizolam: Indication, Dosage, Side Effect, Precaution | CIMS India [Internet]. Mims.com. 2017 [cited 13 June 2017]. Available from:

http://www.mims.com/india/drug/info/etizolam/?type=full&mtype=generic#Indications

Escitalopram: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 1 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a603005.html

DailyMed - ESCITALOPRAM - escitalopram oxalate tablet, film coated ESCITALOPRAM - escitalopram oxalate tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2db02476-325f-ee47-a7e5-b5aed56c364c

[Internet]. 2017 [cited 1 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28957#
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Information on this page was last updated on 27 Aug 2019

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