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Estiva 600 mg Capsule
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Estiva 600 mg Capsule

Manufactured byHetero Healthcare Ltd.
ContainsEfavirenz
Description
Estiva 600 mg Capsule is an antiviral medicine, which is used in combination with other medicines to treat human immunodeficiency virus (HIV) infection. This medicine is not a cure for HIV; it only prevents the virus from multiplying in your body. Monitoring of liver function and kidney function may be necessary while receiving this medicine based on the clinical condition.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Estiva 600 mg Capsule

  • Depression
  • Itching and skin rash
  • Forgetfulness
  • Confusion
  • Headache
  • Difficult or painful urination
  • Pain in the lower back and side
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Trouble sleeping

Uses of Estiva 600 mg Capsule

What is it prescribed for?

  • HIV infection
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is recommended for use in breastfeeding women only in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known history of allergy to efavirenz or any other inactive ingredients present in the formulation.

Severe liver disease

This medicine is not recommended for use in severe liver disease (Child-Pugh Class C), due to the increased risk of adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is recommended for use in breastfeeding women only in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
General warnings

CNS effects

This medicine should be used with caution due to the increased risk of CNS side effects such as hallucinations, dizziness, drowsiness, abnormal dreams, etc. Patients should be closely monitored for any changes in mood or behavior. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Fat redistribution

This medicine may cause fat gain or fat loss from the body. This may result in peripheral wasting, facial wasting, breast enlargement, and Cushingoid appearance. Close monitoring of body weight and body fat distribution is necessary while receiving this medicine. Any changes in the body should be informed to the doctor on priority.

Liver disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypercholesterolemia

This medicine should be used with extreme caution in patients with high cholesterol and triglycerides levels due to the increased risk of worsening of the patient's condition. Frequent monitoring of lipid levels is advised in patients receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Immune reconstitution syndrome

This medicine should be used with caution due to the increased risk of immune reconstitution syndrome. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures and dose adjustments may be necessary based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Citalopram

Fluconazole

Amiodarone

Ciprofloxacin

Azithromycin

Disease interactions

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Increase in cholesterol levels

This medicine should be used with extreme caution in patients with high cholesterol and triglycerides levels due to the increased risk of worsening of the patient's condition. Frequent monitoring of lipid levels is advised in patients receiving this medicine. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

CNS disorders

This medicine should be used with extreme caution in patients with a known history of CNS disorders due to the increased risk of worsening of the patient's condition. Close monitoring of such patients for any change in behavior or mood is recommended. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as directed by the physician. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by stopping the human immunodeficiency virus (HIV) from multiplying. This helps in reducing the chances of the development of acquired immunodeficiency syndrome (AIDS) and other HIV-related illnesses.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Schedule

Schedule H

Efavirenz: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 4 June 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a699004.html

Efavirenz - DrugBank [Internet]. Drugbank.ca. 2020 [cited 4 June 2020]. Available from:

https://www.drugbank.ca/drugs/DB00625

Sustiva 100 mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 4 June 2020]. Available from:

https://www.medicines.org.uk/emc/product/7735/smpc#POSOLOGY

Efavirenz FDA Label - Capsule (gelatin coated), tablet (film coated) [Internet]. AIDSinfo. 2020 [cited 4 June 2020]. Available from:

https://aidsinfo.nih.gov/drugs/269/efavirenz/15/professional
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Information on this page was last updated on 22 Jun 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.