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Espin TM Tablet

Manufactured byINTAS PHARMACEUTICALS LTD
ContainsS-Amlodipine (2.5 mg) + Telmisartan (40 mg)
Description
Espin TM Tablet is a combination of S-Amlodipine and Telmisartan . It is an anti-hypertensive medicine used for the treatment of high blood pressure. This medicine works by relaxing the blood vessels, making the blood flow easily, thus lowering blood pressure. This will reduce your risk of having a heart attack or a stroke by making it easier for your heart to pump blood throughout your body. Espin TM Tablet shows some common side effects like swelling in your ankles or feet, dizziness, back pain, headache, sleepiness, nausea, diarrhoea and stomach pain. Most of these are temporary and usually resolve with time. Espin TM Tablet is also known to cause sleepiness and dizziness, so you should not drive or do any activity that requires mental focus after taking medicine. Avoid consuming alcohol with this medicine as it can worsen dizziness. Espin TM Tablet can be taken with or without food. The dose will be decided by your doctor depending on your blood pressure levels. Avoid abrupt discontinuation of the treatment as your blood pressure may increase if you do so. Espin TM Tablet is not recommended for use if you are allergic to it. If you have any pre-existing kidney or liver problems, or other medical conditions, inform your doctor about them. Inform your doctor about all medicines and supplements you are taking as this medicine can interact with them and can cause side effects. Espin TM Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, or are breastfeeding.

Side effects

Major & minor side effects for Espin TM Tablet

  • Difficulty or painful urination
  • Abdominal pain
  • Muscle pain
  • Difficulty in breathing
  • Dizziness
  • Irregular heartbeat
  • Chest tightness
  • Black or Tarry stools
  • Blurred vision
  • Diarrhoea
  • Indigestion
  • Trouble sleeping

Uses of Espin TM Tablet

What is it prescribed for?

  • Hypertension
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You may start to feel better in 1-2 hours after taking Espin TM Tablet.
  • How long do the effects of this medicine last?
    The effect of Espin TM Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment of Espin TM Tablet as it may cause a further decrease in your blood pressure. You may experience symptoms such as dizziness, fainting, change in heart rate, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Espin TM Tablet.
  • Can this medicine be taken during pregnancy?
    Espin TM Tablet is not recommended for use in pregnancy as it can harm your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Espin TM Tablet is not recommended for use while breastfeeding as it is not known if this medicine passes into breast milk. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Espin TM Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially in the face, lips, throat, etc.), dizziness, breathing difficulty, etc.

Aliskiren

Aliskiren (a medicine used for reducing high blood pressure) is a first-line medicine used in the treatment of hypertension. Taking Espin TM Tablet and Aliskiren together is not recommended as it may lead to kidney damage, increase in your blood pressure and hyperkalaemia (high potassium levels in the blood). This may cause other side effects such as irregular heartbeat, muscle paralysis, heart attack, etc. This risk is especially higher in the elderly population, in people with diabetes and kidney problems.
Warnings for special population

Pregnancy

Espin TM Tablet is not recommended for use in pregnancy as it can harm your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Espin TM Tablet is not recommended for use while breastfeeding as it is not known if this medicine passes into breast milk. Consult your doctor if you are breastfeeding.
General warnings

Hypotension

Espin TM Tablet should be used with caution as it may cause hypotension (low blood pressure). The risk is especially higher if you have low levels of sodium in your body or if you have low fluid volumes due to excessive vomiting, diarrhoea, kidney failure, etc. Hence, regularly monitor your blood pressure while you are taking this medicine.

Hyperkalemia

Espin TM Tablet may cause hyperkalaemia (high blood potassium levels). This may increase your risk of heart rhythm problems. It is recommended to avoid potassium-rich foods (potatoes, bananas, etc) and other medicines that may increase potassium levels during treatment with this medicine.

Use in Children

Espin TM Tablet is not recommended for use in children less than 18 years of age since the safety and efficacy of its use are not clinically established.

Kidney impairment

Espin TM Tablet should be used with caution if you have severe kidney problems. This medicine is filtered and excreted through the kidneys. Using this medicine while you have kidney problems will damage your kidneys and worsen your condition.

Impaired liver function

Espin TM Tablet is metabolized and broken down by the liver and should be used with caution if you have pre-existing liver problems (mild to moderate) due to the increased risk of undesired side effects, resulting from the accumulation of this medicine in your body. Your liver function needs to be closely monitored and dose adjustments may be required based on your clinical condition.

Driving or Operating machines

Espin TM Tablet may cause dizziness or drowsiness. It is advised that you do not perform any activities that require high mental alertness like driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose of Espin TM Tablet as soon as you remember. If it is time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose of Espin TM Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment of Espin TM Tablet as it may cause a further decrease in your blood pressure. You may experience symptoms such as dizziness, fainting, change in heart rate, etc.
Interaction with Medicine

Captopril

Insulin

Carbamazepine

Itraconazole

Rifampicin

Disease interactions

Congestive heart failure

Espin TM Tablet should be taken with caution if you have a history of congestive heart failure since it may worsen the condition. Your doctor may closely monitor your blood pressure, electrolyte level, and heart function during treatment with this medicine.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Espin TM Tablet due to the increased risk of severe side effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
Take Espin TM Tablet exactly as prescribed by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Espin TM Tablet is a combination of S-Amlodipine and Telmisartan . Both medicines works differently to relax the blood vessels and improve blood flow. Thus, this combination is effective in reducing blood pressure. It is used when a single medicine is not sufficient to control your blood pressure.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Angiotensin receptor blockers, Antihypertensive combinations

Schedule

Schedule H

Amlodipine: Medlineplus drug information (no date) MedlinePlus. U.S. National Library of Medicine. Available at: (Accessed: October 31, 2022).

https://medlineplus.gov/druginfo/meds/a692044.html

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use TELMISARTAN TABLETS safely and effectively. See full prescribing information for TELMISARTAN TABLETS . TELMISARTAN tablets, for oral use Initial U.S. Approval: 1998. [online] Available at: [Accessed 16 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e1a907a7-fad9-a860-8639-4c6136c85734

Drugs, H., 2021. Telmisartan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 16 August 2021].

https://medlineplus.gov/druginfo/meds/a601249.html
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Information on this page was last updated on 5 Jan 2023

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