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Esocard Injection
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Esocard Injection

Manufactured bySAMARTH LIFE SCIENCES PVT LTD
ContainsEsmolol
Description
Esocard Injection is a short-acting antihypertensive drug used to treat certain heart rhythm disorders such as supraventricular tachycardia, increased heart rate, and blood pressure occurring during anesthesia and/or surgery. This medicine is not recommended for use in children below 18 years of age. This medicine should not be used in patients with conditions such as heart failure, pulmonary hypertension, etc.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Esocard Injection

  • Dizziness
  • Headache
  • Confusion
  • Anxiety
  • Decreased blood pressure
  • Nausea and Vomiting
  • Dry mouth
  • Increased sweating
  • Unusual tiredness or weakness

Uses of Esocard Injection

What is it prescribed for?

  • Supraventricular Tachycardia
  • Hypertension during surgeries
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 2-10 of administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 10-30 minutes.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving this medicine as it may increase the risk of adverse effects and lowers the blood pressure. Symptoms like a headache, dizziness, change in pulse or heart rate should be reported to the doctor. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use during pregnancy unless absolutely necessary. All the potential benefits and risks should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition

Allergy

This medicine is not recommended for use in patients with a known allergy to esmolol or any other inactive ingredients present along with it.

Sinus Bradycardia

This medicine is not recommended for use in patients with sinus bradycardia which is a condition with decreased heart rate due to the increased risk of worsening of the patient's condition.

Heart block greater than first degree

This medicine is not recommended for patients with severe heart block due to the increased risk of worsening of the patient's condition.

Heart failure

This medicine is not recommended for patients with heart failure due to the increased risk of worsening of the patient's condition.

Asthma/COPD

This medicine is not recommended for use in patients with asthma or chronic obstructive pulmonary disorder due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use during pregnancy unless absolutely necessary. All the potential benefits and risks should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
General warnings

Hypotension

This medicine should be used with caution as it may increase the risk of hypotension. Close monitoring of blood pressure is required. Adequate dose adjustments and suitable alternatives are considered when there is a drastic decrease in blood pressure.

Hyperkalemia

This medicine may cause elevated serum potassium levels in body and development of hyperkalemia especially in patients with risk factors (eg, renal impairment). Close monitoring of serum potassium levels during the therapy is required.

Extravasation

Check for needle or catheter placement before infusion. Avoid extravasation because it leads to cell damage. Avoid infusion to smaller veins and use an alternate infusion in case of a local infusion site reaction to avoid severe reactions like necrosis, blistering, and thrombophlebitis at the injection site.

Abrupt withdrawal

Abrupt withdrawal of this medicine should be avoided, but gradual tapering should be done to avoid acute tachycardia, hypertension, and/or ischemia. Severe exacerbation of angina, ventricular arrhythmias, and myocardial infarction (MI) have been reported following abrupt withdrawal of beta-blocker therapy.

Peripheral Vascular Disease

This medicine should be used with caution in patients with peripheral vascular disease due to the increased risk of adverse effects. An alternative treatment option should be considered in some cases based on the clinical condition.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Since this medicine is administered before and during a surgical procedure by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine as it may increase the risk of adverse effects and lowers the blood pressure. Symptoms like a headache, dizziness, change in pulse or heart rate should be reported to the doctor. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Insulin

Phenobarbital

Clonidine

Amlodipine

Diltiazem

Disease interactions

Asthma/ COPD

This medicine should not be used in patients suffering from bronchial asthma or Chronic Obstructive Pulmonary Disease due to the increased risk of worsening of the patient's condition. Report the incidence of Asthma to your doctor so that this medicine can be substituted with another appropriate medication.

Diabetes

This medicine should be administered with caution in patients with diabetes due to the increased risk of low blood glucose levels. It may mask the hypoglycemic symptoms. You may require a dose adjustment and more frequent clinical monitoring of blood glucose levels while receiving this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Glaucoma

This medicine should be administered with caution in a patient suffering from Glaucoma due to the increased risk of adverse effects. You may require a dose adjustment of current Glaucoma medicine and more frequent clinical monitoring while receiving this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Hyperthyroidism

This medicine should be used with caution in patients having high thyroid hormone levels due to the increased risk of adverse effects. Special caution should be taken while withdrawing this medicine to avoid the risk of thyrotoxicosis. The dosing and effects of the medicine should be closely monitored while receiving this medicine.

Myasthenia Gravis

This medicine should be used with caution in patients suffering from this condition characterized by severe muscle weakness due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Pheochromocytoma

This medicine should be used with caution in patients suffering from pheochromocytoma due to the increased risk of adverse effects. Your doctor may start the therapy with an alpha-blocking agent prior to initiate this medicine with an appropriate dosing and clinical monitoring.

Psoriasis

This medicine should be used with caution in patients suffering from this psoriasis since this medicine may worsen the condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Kidney dysfunction

This medicine should be used with caution in patients with renal dysfunction as the elimination of this medicine is altered and there might be chances for drug accumulation in the body. Regular monitoring of the kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alterantive may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the blood vessels and slowing the heartbeat. This results in an improved blood flow to the heart and reduced high blood pressure.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Cardioselective beta blockers, Group II antiarrhythmics

Schedule

Schedule H

[Internet]. Dailymed.nlm.nih.gov. 2018 [cited 6 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=01ad7942-99c3-40ee-9cfb-272fb6c44e2b

[Internet]. Medicines.org.uk. 2018 [cited 6 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/1803/smpc#

[Internet]. Ebs.tga.gov.au. 2018 [cited 6 September 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-01967-3
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Information on this page was last updated on 7 Jan 2019

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