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Esnil-M Tablet

Manufactured byDEWCARE CONCEPT PVT LTD
ContainsDrotaverine (80 mg) + Mefenamic acid (250 mg)
Description
Esnil-M Tablet contains drotaverine and mefenamic acid. This medicine is used to relieve pain, spasm, or twitches of the smooth muscles in the gut (stomach and intestines) as well as bloating, cramps, and discomfort in the abdomen. It may also be used for reducing pain caused by the kidney and ureter (the tube that connects the kidney to the bladder) stones. Esnil-M Tablet works by relaxing the muscles of the stomach and intestines. It also stops the release of certain chemical messengers that cause pain in the body. Common side effects of this medicine are dry mouth, constipation, diarrhoea, heartburn, blurred vision, and increased heart rate. Esnil-M Tablet is also known to cause dizziness, so do not drive or perform any activity that requires mental focus after taking medicine. Most of the side effects of this medicine are temporary and usually resolve with time. However, talk to your doctor if these side effects intensify or do not go away with time. Avoid consuming alcohol with this medicine as it can worsen dizziness. Esnil-M Tablet can be taken with food or as instructed by your doctor. You should complete the whole treatment even if you feel better after a couple of doses. If you stop treatment too early your symptoms may come back, and your condition may worsen. Esnil-M Tablet should be used with caution in patients with severe liver, kidney, and heart problems as it can increase the risk of severe side effects. This medicine should also be used with caution in the elderly population as they are more prone to develop side effects. Esnil-M Tablet is not recommended to pregnant and breastfeeding women unless prescribed by a doctor

Side effects

Major & minor side effects for Esnil-M Tablet

  • Nausea and vomiting
  • Diarrhoea
  • Constipation
  • Bloating
  • Headache
  • Dizziness
  • Ringing or buzzing in the ears
  • Blurred vision
  • Weight gain
  • Shortness of breath
  • Peeling and blistering of skin
  • Increased heart rate
  • Dry mouth
  • Yellow coloured eyes or skin
  • Heartburn
  • Bloody and Cloudy urine
  • Excessive tiredness

Uses of Esnil-M Tablet

What is it prescribed for?

  • Abdominal pain
  • Mild to moderate pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Esnil-M Tablet may provide relief within 20-30 minutes of intake.
  • How long do the effects of this medicine last?
    The exact amount of time for which Esnil-M Tablet remains active in the body is not clinically established. You may feel better for 6-8 hours after your dose.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Esnil-M Tablet due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, drowsiness, etc. It is advised that you do not perform activities that require high mental alertness like driving vehicles or operating machines if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Esnil-M Tablet.
  • Can this medicine be taken during pregnancy?
    Esnil-M Tablet is not recommended for use in pregnant women especially in the third trimester as it is known to cross the placental barrier and affect your baby's growth. Use this medicine in pregnancy only if prescribed by your doctor.
  • Can this medicine be taken while breast-feeding?
    Esnil-M Tablet is not recommended for use in breastfeeding women. It can pass into breast milk in small amounts which can harm your baby. Inform your doctor if you are breastfeeding while taking this medicine.

Allergy

Esnil-M Tablet is not recommended if you are allergic to any of the ingredients present in the medicine Allergic symptoms like redness, swelling, breathing difficulty, or hives (painful eruptions that itch and sting) should be reported to your doctor immediately.

Sever liver impairment

Esnil-M Tablet is not recommended for use if you have severe liver problems. This medicine gets broken down and absorbed in the liver. Taking this medicine while you have a pre-existing liver problem will further damage your liver.

Severe kidney disease

Esnil-M Tablet is eliminated through kidneys and hence not recommended for use if you are having severe kidney diseases, due to the risk of further kidney damage.
Warnings for special population

Pregnancy

Esnil-M Tablet is not recommended for use in pregnant women especially in the third trimester as it is known to cross the placental barrier and affect your baby's growth. Use this medicine in pregnancy only if prescribed by your doctor.

Breast-feeding

Esnil-M Tablet is not recommended for use in breastfeeding women. It can pass into breast milk in small amounts which can harm your baby. Inform your doctor if you are breastfeeding while taking this medicine.
General warnings

Other medicines

Esnil-M Tablet may interact with many other medicines and may cause side effects. Hence, it is advised that you report all your current medicines including herbs and supplements to the doctor before beginning treatment with this medicine.

Effects on heart

Esnil-M Tablet can increase the heart rate in some people. It should be used with caution if you have heart or valve problems as the risk of a heart attack, stroke or chest pain is more. in such cases. Inform your doctor about your heart disease before taking this medication.

Fluid retention and oedema

Esnil-M Tablet may cause fluid retention and oedema (fluid accumulation in a part of the body) in some people. This medicine reduces the production of prostaglandin, a chemical that is also partly responsible for maintaining water and salt balance in your body, leading to fluid accumulation. This medicine has to be used with caution if you already have oedema.

Allergic skin reactions

Esnil-M Tablet may cause serious skin allergies without any warnings. These events may be fatal in rare cases. If you experience signs and symptoms like skin rashes, hives (painful eruptions that itch and sting) inform your doctor immediately. The treatment should be discontinued if these symptoms appear.

Hypertension

Esnil-M Tablet may cause an increase in blood pressure levels. This risk is especially higher in people with cardiovascular problems (problems of the heart and blood vessels). This medicine can cause fluid retention and that can increase your blood pressure levels. It is recommended that you closely monitor your blood pressure while on treatment with this medicine.

Driving or operating machinery

Esnil-M Tablet may cause blurred vision, dizziness, or drowsiness in some people. It is advised that you do not perform any activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

If you have forgotten to take the dose of Esnil-M Tablet at the given time, then take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

If you have intentionally or accidentally consumed more than the prescribed amount of Esnil-M Tablet, then you may experience headache, confusion, fever, change in the heartbeat, nausea, vomiting, etc. Contact your doctor immediately in such cases.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Esnil-M Tablet due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, drowsiness, etc. It is advised that you do not perform activities that require high mental alertness like driving vehicles or operating machines if you consume alcohol while taking this medicine.
Interaction with Medicine

Glimepiride

Atropine

Diclofenac

Levodopa

Diazepam

Warfarin

Disease interactions

Asthma

Esnil-M Tablet may trigger an asthmatic attack. If you have asthma, do not take this medicine as it may lead to severe allergic reactions and even an asthmatic attack.

Kidney diseases

Esnil-M Tablet should be used with caution if you have kidney problems. This medicine is eliminated through the kidneys and if you use it while you have a pre-existing kidney problem, it will damage your kidneys further.

Liver disease

People with liver problems need to be careful while taking Esnil-M Tablet due to the risk of liver damage. Your doctor will suggest tests to monitor your liver function.

Porphyria

Porphyria is a genetic disease in which there is a buildup of chemicals called porphyrins related to red blood cell proteins. Esnil-M Tablet should be used with extreme caution if you have porphyria due to the risk of adverse effects.

Gastrointestinal Disorders

Esnil-M Tablet may cause stomach and intestinal bleeding and hence not recommended for use if you have stomach ulcers or gastrointestinal bleeding problems.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Esnil-M Tablet with food to prevent stomach discomfort. Never take more than the prescribed dose. Take this medicine at the same time every day. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Esnil-M Tablet is a combination of two medicines, drotaverine and mefenamic acid. Drotaverine relaxes the muscles in the stomach and intestine to stop sudden muscle spasms and improves the movement of food. Mefenamic Acid stops the release of a chemical called prostaglandins, which cause pain in the body. Thus Esnil-M Tablet relieves pain, cramps and discomfort in the abdomen.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Anticholinergics/antispasmodics

Schedule

Schedule H

Innovexia. Life Sciences PVT. LTD. 2021. [online] Available at: < [Accessed 12 July 2021].

http://www.innovexia.com/product/mefpure-d>

Medicineindia.org. 2021. Drotaverine Pharmacology & Usage Details | Medicine India. [online] Available at: < [Accessed 5 August 2021].

https://www.medicineindia.org/pharmacology-for-generic/291/drotaverine>

Pubchem.ncbi.nlm.nih.gov. 2021. Mefenamic acid. [online] Available at: < [Accessed 5 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Mefenamic-acid#section=ATR-IR-Spectra>
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Information on this page was last updated on 7 Sep 2021

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