Eslicarbazepine

Description

Eslicarbazepine is an anticonvulsant used either alone or in a combination with other medicines for the treatment of partial-onset seizures in adults and children above 4 years of age. It is generally used when conventional seizure therapy proves ineffective.

Side effects

Major & minor side effects for Eslicarbazepine

  • Dizziness and fainting
  • Sense of imbalance
  • Uncontrolled eye movements
  • Unusual tiredness or weakness
  • Sleepiness
  • Forgetfulness
  • Trouble concentrating
  • Slow or slurred speech
  • Shaking of body
  • Nausea or vomiting
  • Constipation
  • Stomach pain
  • Recurrent infections
  • Fever
  • Blistering and peeling of skin
  • Painful sores in mouth, or on tongue or lips
  • Difficulty in breathing
  • Difficulty in swallowing
  • Yellowing of skin and eyes

Uses of Eslicarbazepine

What is it prescribed for?

  • Partial onset seizures
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effects is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine. If the medicine is used, monitor the infant closely for any side effects such as drowsiness, inadequate weight gain, etc.

Allergy

This medicine is not recommended for use in patients with a known allergy to eslicarbazepine, oxcarbazepine, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor will determine the best course of treatment after evaluating the potential benefits and risks associated with the use of this medicine. If the medicine is used, monitor the infant closely for any side effects such as drowsiness, inadequate weight gain, etc.
General warnings

Other medicines

Report the use of all your current medicines, including any herbs and supplements, to the doctor. This should be done to rule out the chances of a possible drug interaction.

Use in children

This medicine is not recommended for use in children below 4 years of age since safety and efficacy of use are not clinically established.

Liver diseases

This medicine should be used with caution and monitoring in patients with a mild to moderate impairment of normal liver function due to the increased risk of severe adverse effects. Use is not recommended if the impairment is severe.

Kidney diseases

This medicine should be used with caution and monitoring in patients with an impairment of normal renal function due to the increased risk of severe adverse effects. Appropriate dose adjustments should be made based on the value of creatinine clearance.

Suicidal behavior and ideation

Use of this medicine may increase the risk of suicidal behavior and ideation, especially in patients with a history of depressive disorders. Patients and caregivers should be informed about the risks involved with the use of this medicine. Any change in mood or behavior should be reported to the doctor. Replacement with a suitable alternative may be necessary based on the patient's clinical condition.

Severe allergic reaction

Use of this medicine may cause some severe and life-threatening allergic reactions. Patients on therapy should be monitored and use of this medicine should be discontinued if another cause for these reactions is not established.

Driving or Operating machinery

Use of this medicine may cause neurological side effects such as dizziness, disturbance in gait and coordination, fatigue, cognitive dysfunction, drowsiness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Withdrawal

Use of this medicine should be withdrawn gradually to minimize the risk of increased seizure frequency and status epilepticus. Do not stop the use of this medicine without consulting your doctor.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not use extra medicine to make up for the missed dose.

Overdose

Contact your doctor or seek emergency medical help in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Quetiapine

Hydrocodone

Alprazolam

Carbamazepine

Clopidogrel

Amiodarone

Ethinyl Estradiol

Spironolactone

Lithium

Dextromethorphan

Levonorgestrel

Atorvastatin

Amobarbital

Disease interactions

Depression

This medicine should be used with extreme caution in patients with a history of depression or depressive disorders. Patients should be monitored for the emergence or worsening of depression, suicidal thoughts, and unusual changes in mood and behavior. Family and caregivers should be warned about the risks and should undergo adequate counseling. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with a mild to moderate impairment of normal liver function due to the increased risk of severe adverse effects. Use of this medicine is not recommended in patients with severe impairment of liver function.

Kidney Disease

This medicine should be used with caution and monitoring in patients with an impairment of normal renal function due to the increased risk of severe adverse effects. Appropriate dose adjustments should be made based on the creatinine clearance values.

Hyponatremia

This medicine should be used with caution and monitoring in patients with an abnormal level of sodium in the blood since it may worsen the patient's condition. Appropriate clinical monitoring is advised during treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor since this may cause seizures.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts on the brain and decreases abnormal excitement in the brain.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Diabenzazepine anticonvulsants

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 28 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022416s000lbl.pdf

Eslicarbazepine [Internet]. Livertox.nih.gov. 2018 [cited 28 September 2018]. Available from:

https://livertox.nih.gov/Eslicarbazepine.htm

Eslicarbazepine acetate [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 28 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Eslicarbazepine_acetate#section=2D-Structure

Eslicarbazepine acetate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 28 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB09119

Find Out More [Internet]. Aptiom. 2018 [cited 28 September 2018]. Available from:

http://www.aptiom.com/

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Information on this page was last updated on 28 Sep 2018

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