Eribulin

Description

Eribulin is used for the treatment of metastatic breast cancer (cancer that has spread to other parts of the body from where it started) in patients who have not adequately responded to other cancer medicines. It is also used for the treatment liposarcoma, a rare type of cancer that begins in the body's fat cells, that cannot be removed by surgery.

Side effects

Major & minor side effects for Eribulin

  • Irregular heartbeat
  • Hair loss
  • Weight loss
  • Depression
  • Constipation or diarrhea
  • Dizziness
  • Trouble sleeping
  • Decreased urination
  • Lack or loss of strength
  • Muscle stiffness
  • Bone pain
  • Fainting

Uses of Eribulin

What is it prescribed for?

  • Breast cancer
  • Liposarcoma
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known allergy to eribulin or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Peripheral neuropathy

This medicine should be used with caution in patients with peripheral neuropathy due to the increased risk of worsening of the patient’s condition. Your doctor may discontinue your therapy if you are diagnosed with grade III or grade IV neuropathy until it is resolved. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. An alternative treatment option may be necessary in some cases based on the clinical condition.

QT prolongation

This medicine may cause prolongation of the QT interval and worsen the patient's condition. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neutropenia

This medicine may cause neutropenia (decrease in white blood cells) in some patients and may increase the risk of serious infections. Report any unusual symptoms such as a fever, chills, sore throat, etc. to the doctor immediately. Close monitoring of blood cell counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

Use of this medicine may cause tiredness, fatigue, or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Infections

Use of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while taking this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. If you miss a scheduled appointment for receiving a dose of this medicine, call your doctor immediately for further instructions.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ondansetron

Live attenuated vaccines and related products

Azithromycin

Amiodarone

Moxifloxacin

Disease interactions

Liver impairment

This medicine should be used with caution in patients with liver function impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by stopping the growth of cancer cells in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antineoplastics, Mitotic inhibitors

Schedule

Schedule H

[Internet]. Medlineplus.gov. 2019 [cited 26 March 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a611007.html

[Internet]. Drugbank.ca. 2019 [cited 26 March 2019]. Available from:

https://www.drugbank.ca/drugs/DB08871

[Internet]. Accessdata.fda.gov. 2019 [cited 26 March 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/201532lbl.pdf

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 4 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.