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Eptus-T 10 Tablet

Manufactured byGLENMARK PHARMACEUTICALS LTD
ContainsEplerenone (25 mg) + Torsemide (10 mg)
Description

Eptus-T 10 Tablet is a combination medicine, which is used to control hypertension (high blood pressure), and edema associated with congestive heart failure. This medicine is not recommended for use in patients below 18 years of age.

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Side effects

Major & minor side effects for Eptus-T 10 Tablet

  • Diarrhea
  • Dry mouth
  • Loss of appetite
  • Muscle pain
  • Nausea or vomiting
  • Dizziness
  • Skin rash
  • Acid or sour stomach
  • Chest pain
  • Tingling of hands and feet
  • Confusion
  • Irregular heartbeat
  • Headache
  • Cough
  • Breast enlargement

Uses of Eptus-T 10 Tablet

What is it prescribed for?

  • Hypertension
  • Congestive Heart Failure
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to eplerenone, torsemide, or any other inactive ingredients present in the formulation.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Volume and electrolyte depletion

This medicine may alter the blood volume levels and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolyte levels is necessary while taking this medicine. Report any symptoms such as weakness, lethargy, muscle pain, drowsiness, dizziness, irregular heartbeat, etc. to the doctor immediately.

Hyperkalemia

This medicine may increase potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Hearing problem

Use of this medicine may increase the risk of developing a hearing problem in some patients. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Clarithromycin

Metformin

Nonsteroidal anti-inflammatory drugs

Aminoglycoside antibiotics

Angiotensin converting enzyme inhibitors

Tizanidine

Spironolactone

Amiloride

Disease interactions

Diabetes Mellitus

This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired kidney function

This medicine is not recommended for use in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Kidney function should be assessed before initiating treatment. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Impaired liver function

This medicine should be used with extreme caution in patients with liver impairment due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Electrolyte imbalance

This medicine should be used with caution in patients prone to electrolyte imbalances since it may worsen the patient's condition. Close monitoring of electrolyte levels is recommended for such patients. Any electrolyte imbalances should be corrected before initiating therapy. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. Do not take in larger amounts than prescribed. Drink an adequate amount of water. Close monitoring of kidney function and electrolytes levels is necessary during treatment with this medicine. Report any undesired side effects to the doctor. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Eplerenone and Torsemide both increase the excretion of water and sodium through the urine by preventing their reabsorption in the kidneys. Their combination is thus effective in reducing blood pressure and edema.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Loop diuretics, Aldosterone receptor antagonists, Antihypertensive combinations

Schedule

Schedule H

Eplerenone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 28 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a603004.html

Eplerenone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 28 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00700

DailyMed - Eplerenone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 28 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cd6cbf0b-34b8-43aa-8037-360480a19cf8

Torsemide Oral: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 23 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601212.html

[Internet]. Dailymed.nlm.nih.gov. 2017 [cited 23 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cf288ad5-d4e7-4b0b-bfd0-41c5327e6984
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Information on this page was last updated on 10 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.