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Epotin 40000 IU Injection

Manufactured by: Claris Lifesciences Ltd.
Composition: Epoetin Alfa
Prescription Required: Yes
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Description

Epotin 40000 IU Injection is a synthetic form of a protein that regulates the formation of red blood cells in the body. It is used to treat anemia caused due to severe kidney disease or cancer medications. It is also used during certain surgeries to decrease the need for blood transfusion.

Side effects

Major & minor side effects for Epotin 40000 IU Injection

  • Fever
  • Nausea
  • Vomiting
  • Mouth sores
  • Headache
  • Muscle or joint pain
  • Cough
  • Diarrhea
  • Swelling and redness at the injection site
  • Stomach discomfort and pain
  • Severe skin allergysevererare
  • Swelling of face, lips, eyelids, tongue, hands and feet severerare
  • Difficulty in breathingsevere
  • Wheezingsevererare
  • Dizziness and faintingsevere
  • Upper respiratory tract infectionrare
  • Difficulty in swallowingsevererare
  • Increased blood pressure
  • Pure red cell aplasiasevererare
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Epotin 40000 IU Injection

Onset of action

The effect of this medicine can be observed after several days of administration.

Duration of effect

The time for which the effect of this medicine persists is subjected to variations depending on the intended use.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported

Usage in pregnancy?

Use of this medicine is not recommended for pregnant women unless absolutely necessary. All the potential benefits and risks should be considered before administering this medicine. Use of this medicine containing benzyl alcohol as an ingredient and use of multi-dose vial is not recommended for pregnant women.

Usage while breast-feeding?

Use of this medicine is not recommended for women who are breastfeeding an infant unless absolutely necessary. The use of benzyl alcohol containing dosage forms or multi-dose vials are not recommended.

Substitutes

List of substitutes for Epotin 40000 IU Injection

Below is the list of medicines, which have the same composition, strength and form as Epotin 40000 IU Injection, and hence can be used as its substitute.

What is it prescribed for?

Uses of Epotin 40000 IU Injection

  • Chronic kidney disease associated anemia

    Epotin 40000 IU Injection is used to treat anemia in patients having chronic kidney diseases.

  • Chemotherapy associated anemia

    Epotin 40000 IU Injection is used to treat anemia associated with the use of chemotherapy medicines to treat certain specific types of cancer.

  • Anemia due to use of medicines

    Epotin 40000 IU Injection is used to treat anemia associated with the use of Zidovudine to treat HIV infection.

  • Anemia associated with surgery

    Epotin 40000 IU Injection is also used before and after certain surgeries where chances of significant blood loss is high. It reduces the dependency on blood transfusion process.

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When not to use?

Contraindications of Epotin 40000 IU Injection

  • Allergy

    This medicine is not recommended for use if you have a history of allergy to epoetin alfa or albumin or any other ingredient present in the dosage form.

  • Non-chemotherapy associated anemia in cancer patients

    This medicine is not recommended for use to treat anemia in cancer patients who are are not receiving any chemotherapy medication.

  • High blood pressure

    This medicine is not recommended for use in patients who have high blood pressure and are not taking any medicine to control it.

  • Pure red cell aplasia

    This medicine is not recommended for use if the patient has had a history of pure red cell aplasia after using this medicine or other medicines belonging to the Eryhtropoietin class of drugs.

  • Use of multi-dose vials

    Use of multi-dose vials of this medicine is not recommended for children or pregnant women. The risk of severe adverse effects are increasingly high in such cases.

Dosage

  • Missed Dose

    Contact your doctor if you have missed a scheduled dose of this medicine and follow all the instructions given.

  • Overdose

    Contact your doctor immediately if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Disease interactions

  • Hypertension

    severe
    This medicine should be used with caution in patients with elevated blood pressure levels especially if it is uncontrolled. Your doctor will ensure that the blood pressure is under control before the use of epoetin alfa starts.

  • Seizure disorders

    severe
    This medicine should be used with caution in patients suffering from seizure disorders as the risk of adverse effects are significantly high. You may require clinical monitoring at least in the early stages of treatment with epoetin alfa.

  • Blood clotting disorders

    severe
    This medicine should be used with extreme caution in patients with blood clotting disorders since the risks of severe adverse effects are very high. Any disease of the heart and blood vessels should be reported to the doctor before treatment with epoetin alfa is initiated.

  • Hemodialysis

    severe
    This medicine should be administered with caution in patients undergoing hemodialysis. Suitable dose adjustment and clinical monitoring is recommended while giving this medicine.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Epotin 40000 IU Injection alfa as instructed by the doctor and adhere to the dosage changes made in the course of treatment. It is advised to take this medication in the presence of a trained healthcare professional.

Warnings

Warnings for special population

  • Pregnancy

    - Use of this medicine is not recommended for pregnant women unless absolutely necessary. All the potential benefits and risks should be considered before administering this medicine. Use of this medicine containing benzyl alcohol as an ingredient and use of multi-dose vial is not recommended for pregnant women.

  • Breast-feeding

    - Use of this medicine is not recommended for women who are breastfeeding an infant unless absolutely necessary. The use of benzyl alcohol containing dosage forms or multi-dose vials are not recommended.

General warnings

  • Not for immediate effect

    - This medicine should not be used in cases where an immediate increase in red blood cell count is desired.

  • Ongoing cancer treatment

    - This medicine is not recommended for use in patients who are being treated with biological or radiological medications. It is also not recommended for use in patients who are receiving myelosuppressive therapy for a curable form of cancer.

  • Surgery of heart and blood vessels

    - This medicine is not recommended for use in patients who are about to have a surgery of the heart or blood vessels.

  • Autologous blood donation before surgery

    - This medicine is not recommended for use in patients who are giving their own blood for transfusion before surgery.

  • Heart and blood vessel disorders

    - This medicine should be used with caution since it can cause severe to fatal adverse effects especially in patients suffering from a pre-existing condition of the heart and blood vessels.

  • Seizures

    - This medicine can cause seizures in patients suffering from a kidney disorder especially in the early stages of treatment. All such patients should be dosed carefully with appropriate monitoring.

  • Other ingredients

    - This medicine may contain benzyl alcohol or albumin which increases the risk of certain adverse effects and hence should be carefully administered.

  • Multi-dose vials

    - Use of multi-dose vials or vials containing benzyl alcohol is not recommended for small children.

Other details

  • Food timings: Information not available
  • Administration time: Information not available
  • Sleep inducing: Information not available

How it works

This medicine works by stimulating the bone marrow and as a result production of red blood cells is increased.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Recombinant human erythropoietins
Schedule
Schedule H

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Information on this page was last updated on 10 Apr 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.