Enoxaparin

Description

Enoxaparin is an anticoagulant which is used to prevent the blood clots in the legs. It is used in combination with warfarin to treat blood clots. The patient should inform the doctor if having any bleeding disorder and should be aware of possible side effects of this medicine.

Side effects

Major & minor side effects for Enoxaparin

  • Bleeding gums
  • Increased menstrual flow
  • Collection of blood under the skin
  • Fever
  • Bleeding at the injection site
  • Irritability
  • Convulsions
  • Back pain
  • Dizziness
  • Fast heartbeat
  • Diarrhea

Uses of Enoxaparin

What is it prescribed for?

  • Prophylaxis for Deep Vein Thrombosis
  • Deep Vein Thrombosis
  • Prophylaxis for Angina and myocardial infarction
  • Deep Vein Thrombosis Prophylaxis after surgery
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed in 3 to 5 hours.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is recommended for pregnant women only if clearly needed. Careful monitoring of any symptoms of bleeding is necessary.
  • Usage while breast-feeding?
    No sufficient data is available whether it is excreted in human breast milk. This medicine is recommended in breastfeeding women only if clearly needed. A decision should be taken whether to discontinue the treatment or to stop breastfeeding based on the clinical condition.

Allergy

This medicine is not recommended in the patients with a known allergy to Enoxaparin, heparin and pork products.

Bleeding disorder

This medicine is not recommended in the patients with acute major bleeding or any bleeding disorder.
Warnings for special population

Pregnancy

This medicine is recommended for pregnant women only if clearly needed. Careful monitoring of any symptoms of bleeding is necessary.

Breast-feeding

No sufficient data is available whether it is excreted in human breast milk. This medicine is recommended in breastfeeding women only if clearly needed. A decision should be taken whether to discontinue the treatment or to stop breastfeeding based on the clinical condition.
General warnings

Bleeding

This medicine is known to increase the risk of bleeding in the patients with the bleeding disorder, gastrointestinal bleeding, uncontrolled hypertension or any eye disorders.

Impaired liver function

This medicine is known to increase the liver enzymes, therefore, should be used with caution in patients with impaired liver function.

Impaired kidney function

This medicine may increase the risk of bleeding in patients with severe impaired kidney function. Dose adjustments are to be made if CrCl is less than 30 ml/min.

Percutaneous coronary revascularisation procedures

This medicine should be used with caution to minimize the risk of bleeding in patients who had undergone surgical procedures to treat unstable angina, myocardial infarction.

Heparin-Induced Thrombocytopenia

This medicine should be used with caution in patients with the history of heparin-Induced Thrombocytopenia. Discontinue the treatment if the platelet levels are below 1 lakh cells/cubic mm.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Nonsteroidal anti-inflammatory drugs

Angiotensin converting enzyme inhibitors

Disease interactions

Bleeding disorders

This medicine may increase the risk of bleeding in the patients with a genetic bleeding disorder called hemophilia or any unusual bleeding in the gastrointestinal tract. An alternate medicine should be considered based on the clinical condition.

Liver Disease

This medicine may increase the risk of bleeding in the patients with the liver injury. An alternate medicine should be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Enoxaparin as prescribed by the doctor. Do not take this medicine in larger or smaller quantities than recommended. The treatment should be started at lower doses and increase the dose gradually based on the response. Do not stop taking this medicine without informing your doctor.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
It works by inhibiting the clotting factors that causes the blood to clot.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anticoagulants

Schedule

Schedule H

Enoxaparin: Indications, Side Effects, Warnings - Drugs.com [Internet]. Drugs.com. 2017 [cited 13 April 2017]. Available from:

https://www.drugs.com/cdi/enoxaparin.html

[Internet]. 2017 [cited 13 April 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24344

Enoxaparin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 13 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601210.html

DailyMed - ENOXAPARIN SODIUM- enoxaparin sodium injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 13 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3e6bf2b3-9339-4104-bda3-ad86a1949703#section-14

Lovenox (enoxaparin) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 13 April 2017]. Available from:

http://reference.medscape.com/drug/lovenox-enoxaparin-342174

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 13 April 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 13 April 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~7dmrOP:1

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Information on this page was last updated on 18 Apr 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.