Embeta -HT (12.5/50 mg) Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsHydrochlorothiazide (12.5 mg) + Metoprolol (50 mg)
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Description

Embeta -HT (12.5/50 mg) Tablet is a combination medicine used for the treatment of high blood pressure. Frequent monitoring of blood pressure and electrolytes level is necessary during treatment with this medicine.

Substitutes

List of substitutes for Embeta -HT (12.5/50 mg) Tablet

Side effects

Major & minor side effects for Embeta -HT (12.5/50 mg) Tablet

  • Increased urination
  • Abdominal and stomach pain
  • Dry mouth
  • Joint pain, stiffness, and swelling
  • Cramping
  • Chest pain and discomfort
  • Decreased blood pressure
  • Blurred vision
  • Dizziness
  • Slow heart beat
  • Shortness of breath
  • Nausea or vomiting
  • Skin rash

Uses of Embeta -HT (12.5/50 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to hydrochlorothiazide, other sulfonamides, metoprolol, other beta-blockers, or any other inactive ingredients present along with these medicines.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.

Heart diseases

This medicine is not recommended for use in patients with heart diseases such as a heart block, sinus bradycardia, heart failure, cardiogenic shock, or sick sinus syndrome since it may worsen the patient's condition.

Circulatory disorders

This medicine is not recommended for use in patients with circulatory disorders due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Volume and electrolyte depletion

This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Renal diseases

This medicine may cause Azotemia in patients with a known history of severe renal diseases. Close monitoring of kidney function is necessary while taking this medicine. Replacement with a suitable alternative may be required based on the clinical condition.

Major surgery

This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients.

Hyperthyroidism

This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. Do not stop the use of this medicine without consulting your doctor.

Peripheral Vascular Disease

This medicine should be used with caution in patients suffering from peripheral vascular diseases since it may worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Sports

Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Ischemic heart disease

This medicine should not be discontinued abruptly in patients suffering from ischemic heart disease since abrupt discontinuation may worsen the patient's condition. The dosage should be reduced gradually over a period of 1 to 2 weeks along with close monitoring of heart function before discontinuation of therapy.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Diltiazem

Insulin

Aminophylline

Ergotamine

Antidepressants

Nonsteroidal anti-inflammatory medicines

Disease interactions

Diabetes

This medicine should be used with caution in patients with a known history of diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Hyperuricemia

This medicine should be used with caution in patients with a history of gout or chronic renal failure due to the increased risk of hyperuricemia. Close monitoring of uric acid level is recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Asthma

This medicine is not recommended for use in patients with bronchial asthma or chronic obstructive pulmonary disease since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Heart Block

This medicine is not recommended for use in patients with a greater than first-degree heart block unless a permanent pacemaker is present.

Liver disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Glaucoma

This medicine should be administered with caution in patients suffering from glaucoma. A change in the dose of the current glaucoma medicine may be required in some cases. Replacement with a suitable alternative may be necessary based on the clinical condition.

High cholesterol levels

This medicine should be administered with caution in patients having high levels of cholesterol since it may worsen the patient's condition. Close monitoring of cholesterol levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Coadministration of multivitamin with minerals and this combination medicine should be avoided since it may decrease the effects of the medicine. A time gap of at least 2 hours should be maintained between the administration of multivitamin with minerals and this combination medicine to avoid their interaction.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. Do not take in larger amounts than prescribed. It is advised to take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Hydrochlorothiazide increases the excretion of water and sodium through the urine. Metoprolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Antihypertensive combinations, Beta blockers with thiazides

Schedule

Schedule H

DailyMed - Metoprolol succinate and hydrochlorothiazide tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 28 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=20c2caf9-4c2e-42ac-b02c-f220893ec5a1

Metoprolol tartrate 50 mg and hydrochlorothiazide 12.5 mg oral tablet [Internet]. Snomedbrowser.com. 2017 [cited 28 September 2017]. Available from:

https://snomedbrowser.com/Codes/Details/425352000
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