Efonidipine

Description

Efonidipine is a calcium channel blocker, which is used for the treatment of high blood pressure. It is also used in managing chest pain. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.

Side effects

Major & minor side effects for Efonidipine

  • Nausea
  • Slow heart rate
  • Rash
  • Dizziness
  • Headache
  • Edema
  • Low blood pressure
  • Lightheadedness
  • Weakness

Uses of Efonidipine

What is it prescribed for?

  • Hypertension
  • Angina Pectoris
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Efonidipine or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with Kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness, lightheadedness, etc in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during the treatment with this medicine.

Other medicines

Efonidipine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aliskiren

Alfuzosin

Amoxapine

Amiloride

Acarbose

Albiglutide

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver disease due to the increased risk of adverse effects and altered liver enzyme levels. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include dizziness, headache, fainting, etc.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. Do not take in larger or smaller amounts than prescribed. Drink an adequate amount of water. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the blood vessels and reducing the heart rate. This allows the blood to flow smoothly and decreases the blood pressure.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Calcium channel blocking agents

Schedule

Schedule H

Efonidipine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 13 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Efonidipine#

Efonidipine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 13 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB09235

[Internet]. 2018 [cited 13 December 2018]. Available from:

https://drugs.ncats.io/drug/40ZTP2T37Q

[Internet]. Rad-ar.or.jp. 2019 [cited 7 February 2019]. Available from:

http://www.rad-ar.or.jp/siori/english/dl.cgi?n=2418&file=../kusuri_sp_e/610421346_2418_nosp.doc

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Information on this page was last updated on 7 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.