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E 2 0.06% Gel

Manufactured bySun Pharma Laboratories Ltd.
ContainsEstradiol
Description
E 2 0.06% Gel contains female hormone estrogen (female sex hormone). It is used to relieve symptoms occurring after menopause (cessation of menses) such as vaginal dryness/burning/itching, hot flashes, etc. E 2 0.06% Gel shows side effects like stomach pain, headache, changes in weight, oedema (swelling) of legs, breast tenderness, mood alterations including anxiety and depressed mood. E 2 0.06% Gel is recommended to be taken at the same time every day. Your doctor will decide the dosage of this medicine based on the indication you are taking it for. E 2 0.06% Gel is not recommended for use if you have abnormal/unusual vaginal bleeding. Inform your doctor if you have any kidney problems, diabetes, or any other medical conditions. Do not take this medicine if you are pregnant or planning a pregnancy. Inform your doctor if you are breastfeeding to understand its benefits and the risk to your infant.

Substitutes

List of substitutes for E 2 0.06% Gel

Oestrogel 0.06% Gel
Abbott India Ltd.

Side effects

Major & minor side effects for E 2 0.06% Gel

  • Depression
  • Nervousness
  • Headache
  • Abdominal pain
  • Rash
  • Itching of skin
  • Increased sweating
  • Edema at the site of application

Uses of E 2 0.06% Gel

What is it prescribed for?

  • Post menopausal symptoms
  • Vaginal/vulvar atrophy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for E 2 0.06% Gel to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The duration for which E 2 0.06% Gel remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for E 2 0.06% Gel.
  • Can this medicine be taken during pregnancy?
    E 2 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.
  • Can this medicine be taken while breast-feeding?
    E 2 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.

Allergy

Avoid taking E 2 0.06% Gel if you are allergic to it. Allergic reactions are rare; however, contact your doctor immediately if you experience symptoms like rashes, itching/swelling (particularly of your face/tongue/throat), severe dizziness, and breathing difficulty, etc.

Undiagnosed vaginal bleeding

E 2 0.06% Gel is not recommended for use if you have an abnormal vaginal bleeding episode that has not been diagnosed by your doctor. If you have any menstrual abnormalities, consult your doctor first before taking this medicine.

Heart and blood vessel disorder

E 2 0.06% Gel is not recommended if you have an active or history of stroke (decreased blood flow to your brain) or heart attack. This medicine should also be avoided if you have blood clotting issues. E 2 0.06% Gel can lead to an increase in clot formation if taken in higher doses and thus can worsen your condition.

Estrogen-dependent tumor

E 2 0.06% Gel is not recommended if you have cancer that is sensitive to oestrogens, such as breast and cancer of the endometrium (womb lining), or if you are suspected of having it.

Liver disease

Liver tumours are types of cancer that form in the liver. E 2 0.06% Gel is not recommended in liver tumours because long term use of this medicine may worsen your condition.

Porphyria

Porphyria is a disorder resulting from the accumulation of certain chemicals related to blood cell proteins. E 2 0.06% Gel is not recommended in the presence of porphyria.
Warnings for special population

Pregnancy

E 2 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.

Breast-feeding

E 2 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.
General warnings

Breast cancer

E 2 0.06% Gel increases the risks of breast cancer, hence should be used at the lowest doses and the duration of treatment should be kept as low as possible.

Oedema

E 2 0.06% Gel may cause fluid retention or other associated problems in women. Inform the doctor if you experience any symptoms like swelling of your eye, throat, tongue, arms, and feet.

Use in children

E 2 0.06% Gel is not recommended for use in children and adolescents below 18 years of age as safety and efficacy is not known.

Missed Dose

Apply the missed dose of E 2 0.06% Gel as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of E 2 0.06% Gel may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Benzalkonium chloride

Phenobarbital

Disease interactions

Abnormal vaginal bleeding

E 2 0.06% Gel should be avoided when there is abnormal vaginal bleeding. Your doctor may advise this medication once the bleeding stops.

Hypertension

Hypertension is a condition in which your blood pressure level is higher than normal. Use E 2 0.06% Gel with caution if you have hypertension because it may increase the risk of heart attack and stroke (decreased blood flow to your brain).
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of E 2 0.06% Gel as instructed by your doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. The applied gel should be allowed to dry and should not be washed within 1 hour of application.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
E 2 0.06% Gel works by replacing or replenishing the hormone estrogen (sex hormone) that is normally produced in your body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Estrogens

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Estradiol. [online] Available at: < [Accessed 17 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Estradiol>

Medicines.org.uk. 2021. Oestrogel Pump-Pack 750 micrograms/actuation Gel - Patient Information Leaflet (PIL) - (emc). [online] Available at: < [Accessed 21 October 2021].

https://www.medicines.org.uk/emc/product/353/pil#>
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Information on this page was last updated on 25 Oct 2021

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