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Durogesic D-Trans 25 mcg/hr Transdermal Patch
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Durogesic D-Trans 25 mcg/hr Transdermal Patch

Manufactured byJohnson & Johnson
ContainsFentanyl
Description
Durogesic D-Trans 25 mcg/hr Transdermal Patch is used in the treatment of severe opioid responsive pain conditions in patients who have not adequately responded to non-opioid analgesics.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Durogesic D-Trans 25 mcg/hr Transdermal Patch

  • Blurred vision
  • Chest pain
  • Confusion
  • Dizziness
  • Irregular heartbeat
  • Lightheadedness
  • Nausea or Vomiting
  • Sudden swelling of hands, feet and ankles
  • Change in mood
  • Loss of appetite

Uses of Durogesic D-Trans 25 mcg/hr Transdermal Patch

What is it prescribed for?

  • Moderate to severe pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Has a high potential for abuse. Abuse may lead to severe psychological or physical dependence.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Fentanyl or any other inactive ingredients present in the formulation.

Respiratory depression

This medicine is not recommended for use in patients with respiratory depression due to the increased risk of worsening of the patient's condition.

Gastrointestinal obstruction

This medicine is not recommended for use in patients with gastrointestinal obstruction including paralytic ileus due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Infectious diarrhea

This medicine should be used with extreme caution in patients with infectious diarrhea since it may worsen the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Exposure to heat or sunlight

Avoid exposing the transdermal system application site and the surrounding area to direct sunlight, heaters, electric blankets, or hot tube, etc. Exposure may increase the release of this medicine that may cause adverse effects.

Driving or operating machinery

This medicine may cause difficulty in concentrating, drowsiness, dizziness, confusion, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Drug dependence

This medicine has the potential to cause drug dependence and abuse. This risk is especially higher if the medicine is used for a prolonged period of time. Patients should be monitored closely for any change in mood and behavior during treatment with this medicine. Abrupt discontinuation is not recommended since it may cause withdrawal symptoms.

Missed Dose

It is advised to contact the doctor immediately if you miss a dose of this medicine for further details.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Clonazepam

Bupropion

Amitriptyline

Chlordiazepoxide

Diazepam

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypotension

This medicine should be used with extreme caution in patients with hypotension due to the increased risk of orthostatic hypotension. Regular monitoring of blood pressure, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Intracranial pressure

This medicine should be used with extreme caution in patients with head injury, intracranial lesions, or increased intracranial pressure due to the increased risk of worsening of the patient's condition. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Addison's Disease

This medicine should be used with caution in patients with a known history of Addison's disease due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypothyroidism

This medicine should be used with caution in patients with hypothyroidism (a condition where the thyroid gland does not make enough hormones) due to the increased risk of respiratory depression and prolonged CNS depression. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Urinary tract obstruction

This medicine should be used with caution in patients with urinary retention, prostatic hypertrophy or urethral stricture due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by blocking pain signals from the body to the brain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Narcotic analgesics

Schedule

Schedule H

Fentanyl [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 12 December 2018]. Available from:

https://www.ncbi.nlm.nih.gov/books/NBK459275/

[Internet]. Accessdata.fda.gov. 2018 [cited 12 December 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019813s069lbl.pdf

DailyMed - Fentanyl patch [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 11 February 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2a2238e9-4b5d-c56d-8663-dd354ff9ae0c

Fentanyl - DrugBank [Internet]. Drugbank.ca. 2020 [cited 4 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB00813
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Information on this page was last updated on 4 Mar 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.