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Duorandil 10 mg Tablet

Manufactured byMedreich Lifecare Ltd.
ContainsNicorandil
Description

Duorandil 10 mg Tablet is used for the symptomatic treatment of a heart disease called angina pectoris (chest pain). It is used in patients who are not adequately responded or who cannot tolerate the first-line antianginal medications such as beta-blockers and/or calcium antagonists. It is not recommended for use in children.

Side effects

Major & minor side effects for Duorandil 10 mg Tablet

  • Yellowing of skin and eyes
  • Increase in the potassium levels
  • Watery eyes
  • Gastric Ulcer
  • Decreased blood pressure
  • Nausea and vomiting
  • Fatigue
  • Headache
  • Dizziness and Drowsiness
  • Mouth ulcers
  • Irregular heartbeat
  • Flushing or redness of skin

Uses of Duorandil 10 mg Tablet

What is it prescribed for?

  • Angina pectoris
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of very low blood pressure, dizziness, and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Nicorandil or any other inactive ingredients present along with the formulation.

Hypovolemia

This medicine is not recommended for use in patients with hypovolemia (low blood volume) due to the increased risk of worsening of the patient's condition.

Acute pulmonary edema

This medicine is not recommended for use in patients with acute pulmonary edema (excess fluid in the lungs) due to the increased risk of worsening of the patient's condition.

Cardiogenic shock

This medicine is not recommended for use in patients with cardiogenic shock due to the increased risk of worsening of the patient's condition.

Severe hypotension

This medicine is not recommended for use in patients with severe hypotension (low blood pressure) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving or operating machinery

This medicine may cause side effects such as low blood pressure, drowsiness, weakness, and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during treatment with this medicine.

Ulcerations

This medicine may cause ulcerations in different locations, including skin, conjunctiva, cornea, and the gastrointestinal tract. Therapy should be discontinued if the ulcerations are persistent and refractory to treatment.

Use in children

This medicine is not recommended for use in children since the safety and efficacy are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of very low blood pressure, dizziness, and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Corticosteroids

Riociguat

Nonsteroidal anti-inflammatory medicines

Phosphodiesterase 5 (PDE) inhibitors

Vasodilators

Disease interactions

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients with a history of gastrointestinal diseases due to the increased risk of worsening of the patient's condition. Any gastrointestinal symptoms such as blood in the stool, abdominal pain, abdominal cramps, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by improving the blood flow through the blood vessels of the heart, reducing the workload on the heart and relieving the symptoms of pain.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antianginal agents, Potassium channel activators

Schedule

Schedule H

[Internet]. 2017 [cited 21 August 2017]. Available from:

https://www.medicines.org.uk/emc/PIL.28327.latest.pdf

Nicorandil - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB09220

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2017 [cited 21 August 2017]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-05843-3&d=2017082116114622483

Nicorandil [Internet]. Pubchem.ncbi.nlm.nih.gov. 2020 [cited 16 April 2020]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/47528
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Information on this page was last updated on 28 Apr 2020

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