Duorandil 10 mg Tablet

Manufactured byMedreich Lifecare Ltd.
ContainsNicorandil
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Valid on prescription medicines, only for first time user
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Description

Duorandil 10 mg Tablet is used to prevent or reduce the pain and strain on the heart caused by certain cardiovascular disorders. It is used in patients who cannot take certain other cardiovascular drugs called beta-blockers. It is also used for patients in whom the pain is not adequately controlled by other agents. This medicine is not recommended for use in children.

Side effects

Major & minor side effects for Duorandil 10 mg Tablet

  • Hypersensitivity
  • Yellowing of skin and eyes
  • Increase in the potassium levels
  • Watery eyes
  • Gastric Ulcer
  • Hypotension
  • Nausea and vomiting
  • Fatigue
  • Headache
  • Dizziness and Drowsiness

Uses of Duorandil 10 mg Tablet

What is it prescribed for?

  • Angina pectoris
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    It is recommended that you do not consume alcohol during treatment with this medicine due to the increased risk of very low blood pressures, dizziness, and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if alcohol and Duorandil 10 mg Tablet are used together.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to Duorandil 10 mg Tablet or any other components present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Other Medicines

Since Duorandil 10 mg Tablet may interact with many medicines and may cause severe side effects, it is advised that you report all your current medicines including any herbs and supplements to the doctor before beginning treatment with this medicine.

Drowsiness

This medicine may cause side effects such as low blood pressure, drowsiness, and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery during treatment with this medicine. Appropriate dose adjustments may be necessary based on the clinical condition of the patient.

Ulcerations

This medicine may cause ulcerations in different locations, including skin, conjunctiva, cornea, and the gastrointestinal tract. Therapy with Duorandil 10 mg Tablet should be discontinued if the ulcerations are persistent and refractory to treatment.

Cardiovascular Diseases

This medicine should be used with extreme caution in patients with a history of cardiovascular diseases such as cardiogenic shock or acute myocardial infarction due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

If a dose of the oral form (tablet) of this medicine is missed, take the dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Since the injection form of this medicine is administered in the hospital/clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Oral forms: Seek emergency medical treatment or contact the doctor in case of an overdose with this medicine. Injections: Since the injection form of this medicine is administered in the hospital/clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

It is recommended that you do not consume alcohol during treatment with this medicine due to the increased risk of very low blood pressures, dizziness, and drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if alcohol and Duorandil 10 mg Tablet are used together.
Interaction with Medicine

Corticosteroids

Riociguat

NSAIDs

Phosphodiesterase 5 (PDE) inhibitors

Vasodilators

Disease interactions

Gastrointestinal Disorders

This medicine should be used with extreme caution in patients with a history of gastrointestinal diseases due to the increased risk of worsening of the patient's condition. Any gastrointestinal symptoms such as blood in the stool, abdominal pain, abdominal cramps, etc. should be reported to the doctor on priority. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Follow all the instructions given by your doctor. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. The injection form of this medicine should be administered by a qualified healthcare professional.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Duorandil 10 mg Tablet works by improving the blood flow through the blood vessels of the heart, reducing the workload on the heart and relieving the symptoms of pain.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antianginal agents, Potassium channel activators

Schedule

Schedule H

[Internet]. 2017 [cited 21 August 2017]. Available from:

https://www.medicines.org.uk/emc/PIL.28327.latest.pdf

Nicorandil - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB09220

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2017 [cited 21 August 2017]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-05843-3&d=2017082116114622483

Nicorandil (substance) [Internet]. Snomedbrowser.com. 2017 [cited 21 August 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/395809002

DBGET Search Result: All databases nicorandil [Internet]. Genome.jp. 2017 [cited 21 August 2017]. Available from:

http://www.genome.jp/dbget-bin/www_bfind_sub?mode=bfind&max_hit=1000&dbkey=all&keywords=nicorandil
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