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Duolin LD Respules
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Duolin LD Respules

Manufactured byCIPLA LTD
ContainsIpratropium (500 mcg) + Levosalbutamol (0.63 mg)
Description
Duolin LD Respules is a combination medicine of Ipratropium and Levosalbutamol. This medicine is used to relieve symptoms such as wheezing, shortness of breath, chest tightness, breathing difficulties, coughing, etc. caused by chronic obstructive pulmonary disease (a lung disorder in which the airflow is blocked leading to breathing difficulty). Duolin LD Respules works by relaxing and widening the muscles in your airways. Duolin LD Respules may cause some side effects like headache, cough, mouth dryness, nausea, constipation, etc. Inform your doctor if the side effects become severe or persist for a long time. Avoid taking Duolin LD Respules if you are allergic to it. Duolin LD Respules should be used in the dose and duration advised by your doctor. For the ease of remembering, use it around the same time every day. Even if you see an improvement in your condition, do not stop taking it. If you discontinue the use of this medicine early, your symptoms may return or worsen. Duolin LD Respules is not recommended for use in children less than 12 years of age. Inform your doctor about any other health issues like liver, kidney, heart troubles or if you are undergoing any medical treatment before taking this medicine. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or are breastfeeding.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Duolin LD Respules

  • Dizziness
  • Bladder pain
  • Wheezing
  • Shortness of breath
  • Constipation
  • Back pain
  • Low blood pressure
  • Cough
  • Headache
  • Blocked or runny nose
  • Sore throat and hoarseness
  • Shaking and trembling of arms and feet
  • Decreased appetite
  • Muscle pain and cramps
  • Nervousness
  • Swelling of eyelids, face, lips, tongue
  • Nausea
  • Skin rash and spotting
  • Chest pain and discomfort
  • Increased heartbeat
  • Difficulty in swallowing
  • Unusual tiredness and weakness
  • Visual disturbances

Uses of Duolin LD Respules

What is it prescribed for?

  • Chronic obstructive pulmonary disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Duolin LD Respules can be observed within one to three minutes of an oral inhalation.
  • How long do the effects of this medicine last?
    The effect of Duolin LD Respules lasts for an average duration of 4 to 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Duolin LD Respules.
  • Can this medicine be taken during pregnancy?
    Duolin LD Respules is not recommended for use in pregnant women unless absolutely necessary. However, consult your doctor if you are pregnant before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Duolin LD Respules is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor before using this medicine.

Allergy

Avoid taking Duolin LD Respules if you are allergic to it. Allergic reactions are very rare to this medicine. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (of the face/tongue/throat), breathing difficulties, etc.

Hypertrophic obstructive cardiomyopathy

Duolin LD Respules is not recommended for use in people with hypertrophic obstructive cardiomyopathy (an abnormal condition of the heart, where the heart muscles become thickened and the heart is not able to pump the blood effectively) due to an increased risk of worsening of your condition.
Warnings for special population

Pregnancy

Duolin LD Respules is not recommended for use in pregnant women unless absolutely necessary. However, consult your doctor if you are pregnant before using this medicine.

Breast-feeding

Duolin LD Respules is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor before using this medicine.
General warnings

Narrow-angle glaucoma

Narrow-angle glaucoma is a condition in which pressure inside your eyes increases. It happens due to fluid build-up caused by blocked drainage canals. Duolin LD Respules is not recommended in people with narrow-angle glaucoma as it may increase the risk of mydriasis (a condition in which the pupil of the eye gets widened due to increased eye pressure).

Urinary Retention

Urinary retention is a condition in which you are unable to empty your bladder (the organ in which the urine is stored) completely. Duolin LD Respules should be used with extreme caution if you have any urinary problems as this medicine can increase the risk of side effects such as urinary retention and urinary hesitancy.

Use in children

Duolin LD Respules is not recommended for use in children less than 12 years of age since the safety and efficacydata of its use are not clinically established.

Other medicines

Duolin LD Respules may interact with many other medicines and may cause side effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Paradoxical bronchospasm

Paradoxical bronchospasm is a condition in which there is constriction of the airways due to the use of bronchodilator medicines (medicine that makes breathing easier by relaxing the muscles in your lungs and widening the airways). Duolin LD Respules has been associated with worsening of asthma symptoms in some instances. Contact your doctor immediately if breathing becomes more difficult after using this medicine. It is advised to discontinue this medicine immediately in such cases.

Excessive use

Duolin LD Respules is strictly recommended for use in the prescribed quantities only; excessive use may cause side effects and may lead to a life-threatening condition.

Use in elderly

Duolin LD Respules should be used with caution in the elderly because the risk of severe side effects is significantly high.

Missed Dose

If you miss a dose of Duolin LD Respules, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact your doctor in case of an overdose of Duolin LD Respules.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Furosemide

Nortriptyline

Doxylamine

Disease interactions

Kidney Disease

Duolin LD Respules should be used with caution if you have a history of kidney problems. This medicine is excreted through urine. Using this medicine while you have kidney problems will lead to its accumulation. This can cause permanent damage to your kidneys and worsen your condition. Inform your doctor about your kidney problems.

Liver Disease

Duolin LD Respules should be used with extreme caution if you have a history of liver problems. This medicine breaks down in your liver and is excreted through urine. If you have a damaged liver, the medicine will get accumulated inside and lead to toxicity and can worsen your condition. Inform your doctor about any liver problems that you have.

Heart Disease

Duolin LD Respules should be used carefully because it has been associated with an increase in heart rate and changes in blood pressure. If you have an active or history of heart problems, inform your doctor.

Diabetes

Duolin LD Respules may increase the blood sugar levels and worsen the symptoms of diabetes (a condition in which blood sugar level is increased). Use it carefully if you have diabetes.

Hypokalemia

Hypokalemia is a decrease in blood potassium levels. Use Duolin LD Respules with caution if you have a history of hypokalemia because it may worsen your condition.

Seizure disorders

A seizure (fits) is a condition in which there is uncontrolled body movement due to an electrical disturbance in the brain. Duolin LD Respules should be used with caution if you have a history of seizures as it can lead to onset or aggravation of seizure attacks.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use Duolin LD Respules exactly as prescribed. The prescribed frequency and duration of uptake are specific as per your needs. Do not use this medicine in larger or smaller quantities or for longer than recommended. Consult your doctor if you experience any side effects. Do not stop the use of this medicine without consulting your doctor. Duolin LD Respules is only for inhalation. The tablet should not be swallowed. It is recommended to be taken every day at the same time. It does not act immediately and should not be used to treat acute respiratory problems.  It may cause mouth dryness. Use mouth rinses, maintain dental hygiene, increase water consumption, and consume sugarless sweets to avoid dry mouth. To avoid fungal infections in your mouth and throat, gargle with warm water after each inhalation. Take the initial dose of Duolin LD Respules under medical supervision because it might induce bronchospasm (wheezing or tightness of the airways) right after usage.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Duolin LD Respules works by relaxing and widening the blocked air passages of your lungs. It improves the amount of airflow to your lungs and makes breathing easier.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Bronchodilator combinations

Schedule

Schedule H

CiplaMed. 2021. DUOLIN LD Respules. [online] Available at: < [Accessed 22 December 2021].

https://ciplamed.com/content/duolin-ld-respules>

Pubchem.ncbi.nlm.nih.gov. 2021. Ipratropium. [online] Available at: < [Accessed 22 December 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Ipratropium>

Pubchem.ncbi.nlm.nih.gov. 2021. Levalbuterol. [online] Available at: < [Accessed 22 December 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Levalbuterol>
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Information on this page was last updated on 11 Jan 2022

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